PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Potri.004G211300.1
Common NameHB2, POPTR_0004s22090g
Organism
Populus trichocarpa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus
Family HD-ZIP
Protein Properties Length: 847aa    MW: 92841 Da    PI: 6.21
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Potri.004G211300.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox57.22.9e-182885457
                        -SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
            Homeobox  4 RttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                          ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Potri.004G211300.1 28 YVRYTAEQVEALERVYAECPKPSSLRRQQLIRECpilaNIEPKQIKVWFQNRRCREKQ 85
                        5789****************************************************97 PP
2START144.78.8e-461633692204
                         HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EE CS
               START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..ga 90 
                         +aee++ e+++ka+ ++  Wv+++ +++g++++ +f+ s+ + g a+ra+g+v  ++    +e+l+d+  W ++++  e+      g  g+
  Potri.004G211300.1 163 IAEETLSEFLAKATGTALEWVQMPGMKPGPDSIGIFSISQRCGGVAARACGLVSLEPK-KIAEILKDRSSWFRDCRNLEVFTMFPAGngGT 252
                         7899******************************************************.6677777777*******9999999998888** PP

                         EEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX CS
               START  91 lqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlp 177
                         ++l +++ +a+++l+p Rd +++Ry+ +l+ g++v++++S++     p     +++vRae+lpSg+li+p+++g s +++v+h +l+++++
  Potri.004G211300.1 253 IELVYSQIYAPTTLAPaRDMWTLRYTTSLENGSLVVCERSLSGYGAGPDaaaAAQFVRAEMLPSGYLIRPCEGG-SIIHIVDHLNLQAWSV 342
                         ******************************************99999988999********************9.**************** PP

                         HHHHHHHHHHHHHHHHHHHHHHTXXXX CS
               START 178 hwllrslvksglaegaktwvatlqrqc 204
                         +++lr+l++s+ a ++k++ a+l++ +
  Potri.004G211300.1 343 PEVLRPLYESSKAVAQKMTIAALRYVR 369
                         ***********************9876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.602.6E-181085IPR009057Homeodomain-like
PROSITE profilePS5007115.2892286IPR001356Homeobox domain
SMARTSM003894.6E-152490IPR001356Homeobox domain
SuperFamilySSF466893.51E-162588IPR009057Homeodomain-like
CDDcd000864.83E-162787No hitNo description
PfamPF000467.6E-162885IPR001356Homeobox domain
CDDcd146863.73E-679118No hitNo description
PROSITE profilePS5084824.162153380IPR002913START domain
CDDcd088751.30E-65157370No hitNo description
Gene3DG3DSA:3.30.530.202.3E-17162365IPR023393START-like domain
SMARTSM002342.0E-38162371IPR002913START domain
SuperFamilySSF559613.43E-30162371No hitNo description
PfamPF018523.4E-43163369IPR002913START domain
PfamPF086705.8E-47697845IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 847 aa     Download sequence    Send to blast
MAMEVAPLHR ESSSSGSINK HLTDDGKYVR YTAEQVEALE RVYAECPKPS SLRRQQLIRE  60
CPILANIEPK QIKVWFQNRR CREKQRKESS RLQTVNRKLT AMNKLLMEEN DRLQKQVSQL  120
VCENGFMRQQ LQTVTTDASC DSVVATPQHS LRDANNPAGL LSIAEETLSE FLAKATGTAL  180
EWVQMPGMKP GPDSIGIFSI SQRCGGVAAR ACGLVSLEPK KIAEILKDRS SWFRDCRNLE  240
VFTMFPAGNG GTIELVYSQI YAPTTLAPAR DMWTLRYTTS LENGSLVVCE RSLSGYGAGP  300
DAAAAAQFVR AEMLPSGYLI RPCEGGSIIH IVDHLNLQAW SVPEVLRPLY ESSKAVAQKM  360
TIAALRYVRQ VAHETSGEVV YGLGRQPAVL RTFNQRLSRG FNDAINGFND DGWSLMNADG  420
AEDVIIAVNS TKNLIGANNS AHSLSFLGGI LCAKASMLLQ NVHPAVLVCF LREHHAEWAD  480
FSVDAYSAAL WKAGSYAYPG MRPMRFTGSQ ITMPLGHTIE QEDLLEVIRL EGHSFAQEDA  540
FVSQDIHLLQ ICSGIDENAV GACSELVFAP IDETFPDDAP LLPSGFRIIS LESKAKDTQE  600
VLTTNCTLDL TSSLEAGLAI NHTAVDGSSC HSLRSVLTIA FQFPFESNLQ DNVATMARQY  660
VRSVISSVQR VAMAISPSGL SPVLGPKLSA GSPEALTLAH WICQSHRQVL LNYHLGAELL  720
RSDSVGGDSV LKHLWHHPDA ILCCSLKSLP VFIFANQAGL DMLETTLVAL QDITLDKIFN  780
ESGRQALYTE FAKLMQQGFA CLPAGICMST MGRNVSYEQA VAWKVLSAEE NAVHCIAFSF  840
VNWSFL*
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed at the earliest stages and throughout LSM initiation and development. In embryo development, expressed at the heart stage until the 'walking stick' stage in the adaxial portion of the cotyledon primordia, the shoot apical meristem (SAM) and the vascular precursor cells of the hypocotyl and root. In developing flowers, expressed first at stage 1 in the center of L3 layer and then expands to the center of L2 and L1 layers. Expressed in the center of flower meristem through stages 4 and 5. At stage 6, expressed in the adaxial side of the carpel primordia and then on the adaxial carpel face. {ECO:0000269|PubMed:11169198}.
UniprotTISSUE SPECIFICITY: Expressed in the interfascicular regions of stem and vascular bundles of young roots and leaves. {ECO:0000269|PubMed:10559440}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPotri.004G211300.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY9196170.0AY919617.1 Populus trichocarpa class III HD-Zip protein 2 (HB2) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024455683.10.0homeobox-leucine zipper protein REVOLUTA
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLQ5D1M50.0Q5D1M5_POPTR; Class III HD-Zip protein 2
STRINGPOPTR_0004s22090.10.0(Populus trichocarpa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66333147
Representative plantOGRP6511671
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Ko JH,Prassinos C,Han KH
    Developmental and seasonal expression of PtaHB1, a Populus gene encoding a class III HD-Zip protein, is closely associated with secondary growth and inversely correlated with the level of microRNA (miR166).
    New Phytol., 2006. 169(3): p. 469-78
    [PMID:16411950]
  2. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  5. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  6. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  7. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]