PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Psi003756

Organism

Picea sitchensis

Taxonomic ID

3332

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea

Family

GRF

Protein Properties

Length: 248aa MW: 27014.9 Da PI: 10.4202

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Psi#S49947230	PU_unref	Unigene	View CDS
PUT-183a-Picea_sitchensis-813	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	81.5	7.7e-26	102	145	1	44
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkske 44 d+epgrCrRtDGKkWRCsr+v++++k+CErH+hrgr+rsrk++e Psi003756 102 DPEPGRCRRTDGKKWRCSRDVVPDQKYCERHMHRGRHRSRKPVE 145 79***************************************998 PP
2	QLQ	58	2.9e-20	31	66	2	37
QLQ 2 aFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 +F++aQ+++L++Q+l++Ky++a PvPpeL+ +i+k Psi003756 31 PFSPAQWEELEHQALIFKYMMACIPVPPELIIPIRK 66 9*********************************86 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	5.5E-12	30	66	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	22.057	31	66	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	6.9E-15	31	65	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	26.898	102	146	IPR014977	WRC domain
Pfam	PF08879	2.8E-22	103	145	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 248 aa Download sequence Send to blast
MPVSSMAMGG EFGVMETGMG MHGVRTGVRP PFSPAQWEEL EHQALIFKYM MACIPVPPEL 60 IIPIRKSLHS LPERSPPLPP HHHLSTLTPW SSFHMGFGGN MDPEPGRCRR TDGKKWRCSR 120 DVVPDQKYCE RHMHRGRHRS RKPVEGHTAA VTSQSNSISA PSSLSLAAAV TTSSNVLARP 180 SISVNSLQKL HQPGPLLGTK NLSFTGSGSQ IQQYPLQAAA GAVTSSSPSA MGNKDYRKGS 240 CWKNGFSH

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed during the early stages of leaf development and expression decreases with the maturation of the leaf. {ECO:0000269\|PubMed:20023165}.
Uniprot	TISSUE SPECIFICITY: Strongly expressed in actively growing and developing tissues, such as roots, upper stems, and shoot tips containing the shoot apical meristem (SAM) and flower buds. Detected in young leaf primordium. Also expressed in mature flowers, but weakly expressed in mature stems and leaves. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:21036927}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:15326298, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:21036927}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003635376.1	1e-57	PREDICTED: growth-regulating factor 1
Swissprot	Q8L8A8	7e-49	GRF2_ARATH; Growth-regulating factor 2
TrEMBL	A0A0M3LBH7	1e-129	A0A0M3LBH7_9SPER; Growth regulating factor 3
STRING	VIT_00s0494g00010.t01	4e-57	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37740.1	1e-46	growth-regulating factor 2

Publications ? help Back to Top
Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]