PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Pbr040135.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
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Family | NAC | ||||||||
Protein Properties | Length: 325aa MW: 37238.3 Da PI: 6.448 | ||||||||
Description | NAC family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | NAM | 173.7 | 5.6e-54 | 5 | 133 | 1 | 128 |
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk...kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk 95 +ppGfrFhPt+eelv +yLk+k+++ +++l +vi ++d+yk+ePwd+++ ++e++ewyfFs++dkky+tg+r+nrat++g+Wkatg+dk+vls Pbr040135.1 5 VPPGFRFHPTEEELVGYYLKRKINSLHIDL-DVIVDIDLYKIEPWDIQArcrLGYSEQNEWYFFSHKDKKYPTGTRTNRATAAGFWKATGRDKAVLS- 100 69****************************.99**************953543344778**************************************. PP NAM 96 kgelvglkktLvfykgrapkgektdWvmheyrl 128 k++ +g++ktLvfykgrap+g+ktdW+mheyrl Pbr040135.1 101 KDNIIGMRKTLVFYKGRAPNGNKTDWIMHEYRL 133 8899***************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SuperFamily | SSF101941 | 1.23E-58 | 3 | 169 | IPR003441 | NAC domain |
PROSITE profile | PS51005 | 57.1 | 5 | 169 | IPR003441 | NAC domain |
Pfam | PF02365 | 1.2E-28 | 6 | 133 | IPR003441 | NAC domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0009735 | Biological Process | response to cytokinin | ||||
GO:0009737 | Biological Process | response to abscisic acid | ||||
GO:0009741 | Biological Process | response to brassinosteroid | ||||
GO:0045491 | Biological Process | xylan metabolic process | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0048759 | Biological Process | xylem vessel member cell differentiation | ||||
GO:0050832 | Biological Process | defense response to fungus | ||||
GO:0071365 | Biological Process | cellular response to auxin stimulus | ||||
GO:0090059 | Biological Process | protoxylem development | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding | ||||
GO:0042803 | Molecular Function | protein homodimerization activity | ||||
GO:0043565 | Molecular Function | sequence-specific DNA binding | ||||
GO:0044212 | Molecular Function | transcription regulatory region DNA binding | ||||
GO:0046982 | Molecular Function | protein heterodimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 325 aa Download sequence Send to blast |
MESCVPPGFR FHPTEEELVG YYLKRKINSL HIDLDVIVDI DLYKIEPWDI QARCRLGYSE 60 QNEWYFFSHK DKKYPTGTRT NRATAAGFWK ATGRDKAVLS KDNIIGMRKT LVFYKGRAPN 120 GNKTDWIMHE YRLQTSEHAP PQASSSTSEM PSLNPKPEEG WVVCRAFKKP SPSHRQGFEA 180 WKHAYVRDHP SSSNFSSEIP MVINPNQGFH QSFGSEEDHF VSNNIFLGNQ LMELPQLESP 240 TISTSFVTKE NVLRSNNIST DDYEAERSNN NSSNQHIDWR NLDNLLEVQL TDRASFSHPS 300 LSSASQNYEQ ETQNNHLLGC FQDL* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
3ulx_A | 2e-48 | 2 | 169 | 12 | 168 | Stress-induced transcription factor NAC1 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death) (PubMed:20935069, PubMed:20488898, PubMed:22037706, PubMed:21284754). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:16103214, PubMed:18445131, PubMed:20488898, PubMed:21498679, PubMed:21284754). Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB103, MYB58, MYB63, MYB83, KNAT7, ASL19 and ASL20 (PubMed:17890373, PubMed:19088331, PubMed:18952777, PubMed:19122102, PubMed:19808805, PubMed:20935069, PubMed:21284754). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17890373, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:18952777, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:19122102, ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:20488898, ECO:0000269|PubMed:20935069, ECO:0000269|PubMed:21284754, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22037706}.; FUNCTION: Required for the soilborne fungal pathogen Verticillium longisporum-induced transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements leading to stunted growth, vein clearing, and leaf chloroses, as well as xylem hyperplasia within the vasculature of leaves, hypocotyls, and roots due to reinitiation of cambial activity and transdifferentiation of xylem parenchyma cells. This developmental reprogramming mediates also an increased drought stress tolerance. {ECO:0000269|PubMed:23023171}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00017 | PBM | Transfer from AT1G71930 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Pbr040135.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: By brassinosteroids (e.g. brassinolide BL), auxin (e.g. 2,4-dichlorphenoxyacetic acid 2,4-D) and cytokinin (e.g. kinetin), with a synergistic effect (PubMed:16103214, PubMed:22345435). Up-regulated in a feed-back loop by ASL20 (PubMed:19088331). Levels are monitored by proteasome-mediated degradation (PubMed:18445131). Repressed by WEE1 upon replication stress to prevent premature tracheary element differentiation (PubMed:21498679). Accumulates during infection by the soilborne fungal pathogen Verticillium longisporum, especially in tissues undergoing de novo xylem formation (PubMed:23023171). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22345435, ECO:0000269|PubMed:23023171}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | - | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | KJ919962 | 0.0 | KJ919962.1 Eriobotrya japonica NAC1 transcription factor (NAC1) mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_009345934.1 | 0.0 | PREDICTED: NAC domain-containing protein 30-like | ||||
Swissprot | Q9C8W9 | 1e-113 | NAC30_ARATH; NAC domain-containing protein 30 | ||||
TrEMBL | A0A0H3VAL9 | 0.0 | A0A0H3VAL9_9ROSA; NAC1 transcription factor | ||||
STRING | XP_009345934.1 | 0.0 | (Pyrus x bretschneideri) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF7138 | 32 | 47 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G71930.1 | 4e-94 | vascular related NAC-domain protein 7 |