PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr034663.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

CAMTA

Protein Properties

Length: 1127aa MW: 126991 Da PI: 5.6539

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr034663.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	179.7	3.4e-56	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrrcy 99 l+ k+rwl++ ei++iL nf+k+++++e+++ p+ gsl+L++rk++ryfrkDG++w+kkkdgktvrE+he+LK g+v+vl+cyYah+een++fqrr+y Pbr034663.1 20 LEAKHRWLRPAEICEILRNFQKFDISSEPANMPPGGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVREAHERLKAGSVDVLHCYYAHGEENENFQRRSY 117 6679******************************************************************************************** PP CG-1 100 wlLeeelekivlvhylevk 118 w+Lee+l++ivlvhy+evk Pbr034663.1 118 WMLEEDLQHIVLVHYREVK 136 **************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	82.195	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	8.8E-80	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	1.1E-49	21	134	IPR005559	CG-1 DNA-binding domain
SuperFamily	SSF81296	1.35E-13	521	625	IPR014756	Immunoglobulin E-set
Pfam	PF01833	2.6E-5	521	624	IPR002909	IPT domain
SuperFamily	SSF48403	2.64E-16	718	834	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	1.71E-12	720	832	No hit	No description
PROSITE profile	PS50297	16.759	723	834	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	3.9E-16	723	835	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	0.041	773	802	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	9.084	773	805	IPR002110	Ankyrin repeat
SMART	SM00248	260	812	842	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	4.25E-8	943	998	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	14	947	969	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.364	949	977	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.052	950	968	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0039	970	992	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.578	971	995	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	2.3E-4	973	992	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1127 aa Download sequence Send to blast
MAEIKRYGLG NQLDIAQILL EAKHRWLRPA EICEILRNFQ KFDISSEPAN MPPGGSLFLF 60 DRKVLRYFRK DGHNWRKKKD GKTVREAHER LKAGSVDVLH CYYAHGEENE NFQRRSYWML 120 EEDLQHIVLV HYREVKGNRT NYNHFKGTEE AVPYSHETEE IALNSEMDNS VSSSFNPNNF 180 QMCSQAADTT SLSSAQASEF EDAESAYKHQ ASSQLQPFLE LLQPKAEKIN AGFSNACYPM 240 SFSNEYQEKL SAVPGVNFSS RTEAYRKEDG NDAGVTYDPR KNLNSAVWDG ALGNITTGFQ 300 SLPFQPSISA THSDSIGIIS QQENETLGHL FTDNFGKKQN YEDKPRVQQS WQTLEANTSG 360 SSSWPVDWNL HSDTAYDVTT RFHGGVDDSN LLNSPVCCVD SEKKNNYSMP NDLQIQPSNT 420 EKEYHLKSIS KRNETIEGKY NHTFATKPLL DEGLKKLDSF NRWMSKELGD VEETHTQSNS 480 ETYWDTVESD NGVDESSIPL QVRLDSYMLG PSLSRDQLFS IIDFSPNWAY ENSEIKVLIT 540 GRFFKSQQAE SCKWSCMFGE VEVPAXXXXX XXXXXXXXXX XXPAEVIADG VLRCYTPIHK 600 AGRIPFYVTC SNRLACSEIR EFEYRVGQIP DYDVKDDYSG CTNEILNMRF GKLLSLSSSS 660 PTFDPTSVAE NSEIISKIDL LLKNDNGEWD KMLQLTSNED FSLERVEDQM LQQLLKEKLH 720 AWLLQKLAAG GKGPSVLDEG GQGVLHFGAA LGYDWVLLPT ITAGVSVNFR DINGWTALHW 780 AAFCGRERTV ASLISLGAAP GLLTDPRTKY PNGRTPADLA SARGHKGIAG YLAESALSDQ 840 LSFLNLDIKE DNNADISGAN AVRTVSEQFA TPIGNGDLMD GLSLRDSLTA VCNATQAAAR 900 IHQVFRVKSF QLKQLKEYGS DNFGISDEDA LSMIAVKSHK PGKRDEHVDA AAIRIQNKFR 960 SWKGRKDYLI IRQRIVKIQA HVRGHQVRKN YRKIVWTVGI VEKIILRWRR KGSGLRGFKP 1020 EPLTEAPSTQ ASSSKDDDYD VLKEGRKQTE QRLQKALARV KSMVQYPEAR DQYCRLLNVV 1080 TEIQETKEVY DSGTTSSEGR VDMDHDFIDI AALLDEEDIY MPTEAP*

Sequence ? help Back to Top

Protein Sequence Length: 1127 aa Download sequence Send to blast

MAEIKRYGLG NQLDIAQILL EAKHRWLRPA EICEILRNFQ KFDISSEPAN MPPGGSLFLF  60
DRKVLRYFRK DGHNWRKKKD GKTVREAHER LKAGSVDVLH CYYAHGEENE NFQRRSYWML  120
EEDLQHIVLV HYREVKGNRT NYNHFKGTEE AVPYSHETEE IALNSEMDNS VSSSFNPNNF  180
QMCSQAADTT SLSSAQASEF EDAESAYKHQ ASSQLQPFLE LLQPKAEKIN AGFSNACYPM  240
SFSNEYQEKL SAVPGVNFSS RTEAYRKEDG NDAGVTYDPR KNLNSAVWDG ALGNITTGFQ  300
SLPFQPSISA THSDSIGIIS QQENETLGHL FTDNFGKKQN YEDKPRVQQS WQTLEANTSG  360
SSSWPVDWNL HSDTAYDVTT RFHGGVDDSN LLNSPVCCVD SEKKNNYSMP NDLQIQPSNT  420
EKEYHLKSIS KRNETIEGKY NHTFATKPLL DEGLKKLDSF NRWMSKELGD VEETHTQSNS  480
ETYWDTVESD NGVDESSIPL QVRLDSYMLG PSLSRDQLFS IIDFSPNWAY ENSEIKVLIT  540
GRFFKSQQAE SCKWSCMFGE VEVPAXXXXX XXXXXXXXXX XXPAEVIADG VLRCYTPIHK  600
AGRIPFYVTC SNRLACSEIR EFEYRVGQIP DYDVKDDYSG CTNEILNMRF GKLLSLSSSS  660
PTFDPTSVAE NSEIISKIDL LLKNDNGEWD KMLQLTSNED FSLERVEDQM LQQLLKEKLH  720
AWLLQKLAAG GKGPSVLDEG GQGVLHFGAA LGYDWVLLPT ITAGVSVNFR DINGWTALHW  780
AAFCGRERTV ASLISLGAAP GLLTDPRTKY PNGRTPADLA SARGHKGIAG YLAESALSDQ  840
LSFLNLDIKE DNNADISGAN AVRTVSEQFA TPIGNGDLMD GLSLRDSLTA VCNATQAAAR  900
IHQVFRVKSF QLKQLKEYGS DNFGISDEDA LSMIAVKSHK PGKRDEHVDA AAIRIQNKFR  960
SWKGRKDYLI IRQRIVKIQA HVRGHQVRKN YRKIVWTVGI VEKIILRWRR KGSGLRGFKP  1020
EPLTEAPSTQ ASSSKDDDYD VLKEGRKQTE QRLQKALARV KSMVQYPEAR DQYCRLLNVV  1080
TEIQETKEVY DSGTTSSEGR VDMDHDFIDI AALLDEEDIY MPTEAP*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr034663.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018499833.1	0.0	PREDICTED: calmodulin-binding transcription activator 3-like
Refseq	XP_018499834.1	0.0	PREDICTED: calmodulin-binding transcription activator 3-like
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A498HVW2	0.0	A0A498HVW2_MALDO; Uncharacterized protein
STRING	XP_009342523.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8284	27	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]