PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009622481.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 374aa    MW: 43434.8 Da    PI: 8.3247
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009622481.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H218.55.6e-066585323
                    ETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                    C+ Cg sF  + +Lk+H+++H
  XP_009622481.1 65 CEECGVSFQKPAHLKQHMQSH 85
                    *******************99 PP

2zf-C2H2188.2e-0693117123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     ++C+  dC  s++rk++L+rH+  H
  XP_009622481.1  93 FVCHidDCQSSYRRKDHLTRHLLQH 117
                     89*******************9887 PP

3zf-C2H214.30.00012122147123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     ++Cp   C++ Fs + n++rH +  H
  XP_009622481.1 122 FECPvdGCKRAFSIQGNMTRHVKEmH 147
                     89********************9988 PP

4zf-C2H218.65e-06161185123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     y+C    Cgk+F+  s Lk+H  +H
  XP_009622481.1 161 YVCAesGCGKVFKFASKLKKHEDSH 185
                     89*******************9888 PP

5zf-C2H218.55.7e-06252276223
                     EET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                     kC+  dC  +Fs+ksnL +H +  H
  XP_009622481.1 252 KCEfqDCQHTFSTKSNLIQHVKAvH 276
                     79999***************99877 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355321638IPR015880Zinc finger, C2H2-like
SuperFamilySSF576673.77E-862117No hitNo description
PROSITE profilePS5015711.1986390IPR007087Zinc finger, C2H2
SMARTSM003550.00956385IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002806585IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.1E-76593IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.41193122IPR007087Zinc finger, C2H2
SMARTSM003550.02793117IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.8E-1094119IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS00028095117IPR007087Zinc finger, C2H2
SuperFamilySSF576671.7E-6103147No hitNo description
Gene3DG3DSA:3.30.160.603.3E-5120148IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.221122152IPR007087Zinc finger, C2H2
SMARTSM003550.0014122147IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280124147IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.0E-7156185IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.023161185IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.928161190IPR007087Zinc finger, C2H2
PROSITE patternPS000280163185IPR007087Zinc finger, C2H2
SMARTSM003559.9193218IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280195218IPR007087Zinc finger, C2H2
SMARTSM0035513221242IPR015880Zinc finger, C2H2-like
SuperFamilySSF576676.73E-10233289No hitNo description
PROSITE profilePS5015713.547251281IPR007087Zinc finger, C2H2
SMARTSM003550.0011251276IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.4E-6252278IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280253276IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.2E-5279304IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM0035510282308IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280284308IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
MGEEKREVIF RDIRRYYCEF CGICRSKKSL ISAHILSHHQ DEMEKRKDEA NEDAKIKEGP  60
KLNICEECGV SFQKPAHLKQ HMQSHSLEIE RPFVCHIDDC QSSYRRKDHL TRHLLQHQGK  120
LFECPVDGCK RAFSIQGNMT RHVKEMHDQR ASPEASLPKQ YVCAESGCGK VFKFASKLKK  180
HEDSHVKLET MEALCLEPGC MKHFTNEKCL KEHVESCHQH IVCEICGTKQ LKKNIKRHLR  240
MHEEESTSER IKCEFQDCQH TFSTKSNLIQ HVKAVHLGDK PFSCRIAGCG MKFAFKHVRD  300
RHEKSGCHVY TPGDFVEADE HFRSRPRGGR KRKLPVFEAI MRKRITPPSG TDPVFYQGSE  360
YLSWLLSAES DEEL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A6e-166721319155PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D6e-166721319155PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1324332RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKX0986000.0KX098600.1 Nicotiana benthamiana transcription factor IIIA 9ZF mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009622481.20.0PREDICTED: transcription factor IIIA-like
SwissprotQ84MZ41e-137TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A1S3YNF60.0A0A1S3YNF6_TOBAC; transcription factor IIIA-like isoform X1
STRINGXP_009622481.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA36442447
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-140transcription factor IIIA