PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_016502760.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
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Family | bHLH | ||||||||
Protein Properties | Length: 679aa MW: 74372.8 Da PI: 5.4452 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 39.1 | 1.3e-12 | 499 | 544 | 4 | 54 |
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YI++L XP_016502760.1 499 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAISYINEL 544 799***********************6.....5***************998 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF14215 | 5.2E-56 | 90 | 273 | IPR025610 | Transcription factor MYC/MYB N-terminal |
PROSITE profile | PS50888 | 17.39 | 495 | 544 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd00083 | 4.45E-15 | 498 | 549 | No hit | No description |
SuperFamily | SSF47459 | 4.58E-18 | 498 | 567 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 4.3E-10 | 499 | 544 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene3D | G3DSA:4.10.280.10 | 4.3E-18 | 499 | 565 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 4.5E-16 | 501 | 550 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 679 aa Download sequence Send to blast |
MTDYSLPTMN LWNTSGTTDD NVSMMESFMS SDLTSFWATS NSTTAAVTSN SNLIPVNTLT 60 VLLPSSCAST VTAVAVDASK SMSFFNQETL QQRLQTLIDG ARETWTYAIF WQSSVVDLSS 120 PFVLGWGDGY YKGEEDKANR KLAVSSPAYI AEQEHRKKVL RELNSLISGT QTGTDDAVDE 180 EVTDTEWFFL ISMTQSFVNG SGLPGQALYN SSPIWVAGAE KLAASHCERA RQAQGFGLQT 240 MVCIPSANGV VELGSTELII QSCDLMNKVR VLFNFNNDLG SGSWAVQPES DPSALWLTDP 300 SSAAVEVQDL NTVKANSVPS SNSSKQVVFD NENNGHSSDN QQQQHSKHET QGFFTRELNF 360 SEFGFDGSSN NRNGNSSLSC KPESGEILNF GDSTKKSANG NLFSGQSHFG AGEENKNKKR 420 SPASRGSNEE GMLSFVSGTI LPAASGAMKS SGGVGEDSDH SDLEASVVKE AESSRVVEPE 480 KRPKKRGRKP ANGREEPLNH VEAERQRREK LNQRFYALRA VVPNVSKMDK ASLLGDAISY 540 INELKLKLQN TETDREELKS QIEDLKKELV SKDSRRPGPP PSNHDHKMSS HTGSKIVDVD 600 IDVKIIGWDA MIRIQCNKKN HPAARLMVAL KELDLDVHHA SVSVVNDLMI QQATVKMGSR 660 LYTEEQLRIA LTSRVAETR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4rqw_A | 5e-70 | 85 | 276 | 4 | 195 | Transcription factor MYC3 |
4rqw_B | 5e-70 | 85 | 276 | 4 | 195 | Transcription factor MYC3 |
4rs9_A | 5e-70 | 85 | 276 | 4 | 195 | Transcription factor MYC3 |
4yz6_A | 5e-70 | 85 | 276 | 4 | 195 | Transcription factor MYC3 |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 480 | 488 | KRPKKRGRK |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1 (PubMed:15231736). Acts as negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth (PubMed:24483714). Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA) (PubMed:24483714). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter (PubMed:24483714). Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses (PubMed:28733419). Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA (PubMed:28733419). With JA2L forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). With ERF.C3 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection (PubMed:28733419). Regulates negatively defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA) (PubMed:30576511). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling (PubMed:30610166). May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels (PubMed:29528226). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24483714, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511, ECO:0000269|PubMed:30610166}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Induced by methyl jasmonate (PubMed:15231736, PubMed:28733419). Induced by wounding (PubMed:15231736). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced in fruit by storage in cold (PubMed:29528226). Induced by hydrogen peroxide and infection with root-knot nematodes (PubMed:30576511). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | GQ859159 | 0.0 | GQ859159.1 Nicotiana tabacum MYC1b transcription factor mRNA, complete cds. | |||
GenBank | HM466974 | 0.0 | HM466974.1 Nicotiana tabacum MYC2a transcription factor mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | NP_001313001.1 | 0.0 | transcription factor MYC2-like | ||||
Swissprot | A0A3Q7HRZ6 | 0.0 | MYC2_SOLLC; Transcription factor MYC2 | ||||
TrEMBL | D7P234 | 0.0 | D7P234_TOBAC; MYC1b transcription factor | ||||
STRING | XP_009609942.1 | 0.0 | (Nicotiana tomentosiformis) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA3300 | 24 | 49 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G32640.1 | 0.0 | bHLH family protein |