PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016494150.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family G2-like
Protein Properties Length: 370aa    MW: 41516.1 Da    PI: 9.4309
Description G2-like family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016494150.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like101.94.1e-32200253255
         G2-like   2 prlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                     pr+rWt+ LH+rFv+ave LGG+e+AtPk++lelm+vk+Ltl+hvkSHLQ+YR+
  XP_016494150.1 200 PRMRWTTSLHARFVHAVELLGGHERATPKSVLELMDVKDLTLAHVKSHLQMYRT 253
                     9****************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.79E-15197253IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.7E-28198253IPR009057Homeodomain-like
TIGRFAMsTIGR015572.2E-23200253IPR006447Myb domain, plants
PfamPF002491.9E-7201252IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 370 aa     Download sequence    Send to blast
MPLEGVFVQP PSSSNPIPDL SLHISPPNSS SSPSSKPTNC LTELSLAHPT TINKEKSLFN  60
SESRTFPRNP LPHQSQNNYL LQQNSQMNNI NNGVSLLDVS SESTLMRPIK GIPIYHQNYS  120
FPNFLEKDPK RFGSLFSPYN FNGSSDHLSN AYRIPMANRF HHHHSQYGVG LGHSNETTSH  180
SYMRSRFLPK FPGKRSMRAP RMRWTTSLHA RFVHAVELLG GHERATPKSV LELMDVKDLT  240
LAHVKSHLQM YRTVKTTDKP AASSGQSDGS SEEDLLKIDR ILDQRGPSDG FDDPSTTTPT  300
LWSNSSSGSR ERWSQANFND ANGLRSTSFP SQQRSGHHIE EREYSRPVSY VGCSLDQRNP  360
SLEFTLGRPD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6j4k_A8e-17201255458Protein PHOSPHATE STARVATION RESPONSE 1
6j4k_B8e-17201255458Protein PHOSPHATE STARVATION RESPONSE 1
6j4r_A8e-17201255357Protein PHOSPHATE STARVATION RESPONSE 1
6j4r_B8e-17201255357Protein PHOSPHATE STARVATION RESPONSE 1
6j4r_C8e-17201255357Protein PHOSPHATE STARVATION RESPONSE 1
6j4r_D8e-17201255357Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_A8e-17201255458Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_C8e-17201255458Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_D8e-17201255458Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_F8e-17201255458Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_H8e-17201255458Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_J8e-17201255458Protein PHOSPHATE STARVATION RESPONSE 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor that regulates lateral organ polarity. Promotes lateral organ abaxial identity by repressing the adaxial regulator ASYMMETRIC LEAVES2 (AS2) in abaxial cells. Required for abaxial identity in both leaves and carpels. Functions with KAN2 in the specification of polarity of the ovule outer integument. Regulates cambium activity by repressing the auxin efflux carrier PIN1. Plays a role in lateral root formation and development. {ECO:0000269|PubMed:11395775, ECO:0000269|PubMed:11525739, ECO:0000269|PubMed:14561401, ECO:0000269|PubMed:15286295, ECO:0000269|PubMed:16623911, ECO:0000269|PubMed:17307928, ECO:0000269|PubMed:18849474, ECO:0000269|PubMed:20179097}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by AS2 in adaxial tissue. {ECO:0000269|PubMed:18849474}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB2209682e-47AB220968.1 Ipomoea nil FE mRNA for KANADI-like transcription factor FEATHERED, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016494150.10.0PREDICTED: transcription repressor KAN1-like isoform X1
SwissprotQ93WJ98e-69KAN1_ARATH; Transcription repressor KAN1
TrEMBLA0A1S4BZ160.0A0A1S4BZ16_TOBAC; transcription repressor KAN1-like isoform X1
STRINGXP_009607646.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24682355
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G16560.12e-56G2-like family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Huang T,Kerstetter RA,Irish VF
    APUM23, a PUF family protein, functions in leaf development and organ polarity in Arabidopsis.
    J. Exp. Bot., 2014. 65(4): p. 1181-91
    [PMID:24449383]
  3. Mach J
    Getting in Shape? Leaves work it out with KANADI1.
    Plant Cell, 2014. 26(1): p. 4
    [PMID:24464293]
  4. Jun SE, et al.
    Comparative analysis of the conserved functions of Arabidopsis DRL1 and yeast KTI12.
    Mol. Cells, 2015. 38(3): p. 243-50
    [PMID:25518926]
  5. Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y
    The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis.
    Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71
    [PMID:26108442]
  6. Xie Y, et al.
    Meta-Analysis of Arabidopsis KANADI1 Direct Target Genes Identifies a Basic Growth-Promoting Module Acting Upstream of Hormonal Signaling Pathways.
    Plant Physiol., 2015. 169(2): p. 1240-53
    [PMID:26246448]
  7. Alvarez JP,Furumizu C,Efroni I,Eshed Y,Bowman JL
    Active suppression of a leaf meristem orchestrates determinate leaf growth.
    Elife, 2017.
    [PMID:27710768]
  8. Singh A, et al.
    Phytohormonal crosstalk modulates the expression of miR166/165s, target Class III HD-ZIPs, and KANADI genes during root growth in Arabidopsis thaliana.
    Sci Rep, 2017. 7(1): p. 3408
    [PMID:28611467]
  9. Caggiano MP, et al.
    Cell type boundaries organize plant development.
    Elife, 2018.
    [PMID:28895530]
  10. Ó'Maoiléidigh DS,Stewart D,Zheng B,Coupland G,Wellmer F
    Floral homeotic proteins modulate the genetic program for leaf development to suppress trichome formation in flowers.
    Development, 2018.
    [PMID:29361563]