PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016486645.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bZIP

Protein Properties

Length: 263aa MW: 29253.9 Da PI: 7.6865

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016486645.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	23.3	1.4e-07	87	130	8	51
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 8 rrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkelee 51 +r +N eA r++R++ ka+++ Le++v L a N++L k+l+ XP_016486645.1 87 KRPLSNEEAVRKYREKNKARVASLEDEVVRLRAINQQLLKRLQG 130 7889************************************9975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	7.1E-4	81	147	IPR004827	Basic-leucine zipper domain
Pfam	PF07716	8.4E-10	83	129	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	3.09E-5	85	128	No hit	No description
Gene3D	G3DSA:1.20.5.170	7.3E-11	85	148	No hit	No description
CDD	cd14686	2.42E-9	86	139	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 263 aa Download sequence Send to blast
MHNRELHFSN QEMGSSSNFG EIPECSSTKR LFNEILSDMH ACIHTHTCNP PGPDNSHTHT 60 CYHVHTKVVP PLSDDTAESA ENKIGKKRPL SNEEAVRKYR EKNKARVASL EDEVVRLRAI 120 NQQLLKRLQG QSVLEAEISK LKCLLVDIRG RIEGDIGFFP YQKPMKSGNI YQNLVNPNYP 180 GAYVMNPCNL QCDDQVYCLQ PGSGELNGQG LNSCGFQTRQ CFLGNQEPKE VTGCAWGYGT 240 PTAEASSGNK RKGGKHEAMA SWS

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the response to zinc ion deficiency. Binds to the consensus sequence 5'-[AG]TGTCGACA[CT]-3' also called zinc deficiency response element (ZDRE). The ZDRE sequence is conserved in the plant kingdom and present in the promoters of genes that constitute the primary response to zinc deficiency, comprising additional ZIP metal transporter genes (PubMed:20479230, PubMed:26306426). Required for zinc accumulation in roots. Mediates the expression of the zinc transporter ZIP12 during growth in zinc-deficient conditions. ZIP12 transporter is involved in zinc uptake in roots (PubMed:26306426). {ECO:0000269\|PubMed:20479230, ECO:0000269\|PubMed:26306426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by zinc deficiency. {ECO:0000269\|PubMed:20479230}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016486645.1	0.0	PREDICTED: basic leucine zipper 23-like
Refseq	XP_016486646.1	0.0	PREDICTED: basic leucine zipper 23-like
Swissprot	Q8GTS2	2e-94	BZP23_ARATH; Basic leucine zipper 23
TrEMBL	A0A1S4BCV2	0.0	A0A1S4BCV2_TOBAC; basic leucine zipper 23-like
STRING	XP_009624365.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2989	24	52

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G16770.1	8e-97	bZIP family protein

Publications ? help Back to Top
Azevedo H, et al. Transcriptomic profiling of Arabidopsis gene expression in response to varying micronutrient zinc supply. Genom Data, 2016. 7: p. 256-8 [PMID:26981422] Castro PH, et al. Phylogenetic analysis of F-bZIP transcription factors indicates conservation of the zinc deficiency response across land plants. Sci Rep, 2017. 7(1): p. 3806 [PMID:28630437] Nazri AZ,Griffin JHC,Peaston KA,Alexander-Webber DGA,Williams LE F-group bZIPs in barley-a role in Zn deficiency. Plant Cell Environ., 2017. 40(11): p. 2754-2770 [PMID:28763829] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]