PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016486337.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family WRKY
Protein Properties Length: 580aa    MW: 64546.8 Da    PI: 7.8393
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016486337.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY103.21.5e-32115171259
                     --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
            WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                     dDgy+WrKYGqK+vkgsefprsYY+Ct+++Cpvkkkvers  d++++ei+Y+g Hnh+
  XP_016486337.1 115 DDGYTWRKYGQKHVKGSEFPRSYYKCTQQNCPVKKKVERSP-DGQITEIVYKGAHNHH 171
                     8****************************************.***************8 PP
2WRKY1031.6e-32327385159
                     ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
            WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                     ldDgy+WrKYGqK+vkg+++prsYY+CtsagCpv+k+ver+ ++   v++tYeg+Hnhe
  XP_016486337.1 327 LDDGYRWRKYGQKVVKGNPNPRSYYKCTSAGCPVRKHVERAPDNLISVITTYEGKHNHE 385
                     59********************************************************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.808.5E-28104172IPR003657WRKY domain
SuperFamilySSF1182901.15E-24110172IPR003657WRKY domain
SMARTSM007743.9E-36114172IPR003657WRKY domain
PfamPF031061.7E-25115171IPR003657WRKY domain
PROSITE profilePS5081122.814115173IPR003657WRKY domain
Gene3DG3DSA:2.20.25.802.1E-35312387IPR003657WRKY domain
SuperFamilySSF1182902.62E-28320387IPR003657WRKY domain
PROSITE profilePS5081136.472322387IPR003657WRKY domain
SMARTSM007745.5E-38327386IPR003657WRKY domain
PfamPF031061.2E-25328385IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 580 aa     Download sequence    Send to blast
MLITLARCSN HTVEIFQAPQ SPTTGSFHFS TINQENTMKT TQIARDHFEF PVESPKATAL  60
KKCSLDIAGE TNVQQNMSCI GLTNIHESGN CARRANQFEQ RSAVTSYKIT CNGSDDGYTW  120
RKYGQKHVKG SEFPRSYYKC TQQNCPVKKK VERSPDGQIT EIVYKGAHNH HKSQPPRRAT  180
MSSTVYGLGE TSEMSEGNIG GSNSWRSVQF ERNKDVRAPS GLDRTSSASV LTKVSDPLML  240
NYQKTNINAF ESAGTTPEPS STLASRDDED EDRATEGSTS LGDDVDDYAF DHKRRRREFY  300
SVETSLSSRT TREPRVVVQI ESEIDILDDG YRWRKYGQKV VKGNPNPRSY YKCTSAGCPV  360
RKHVERAPDN LISVITTYEG KHNHEVPSTN KTNCAISGNQ ALTSTSKTHK VSNLGMQVQD  420
CNFQFNRKPF DYVRPSFLDL RFGATSPIYD LKFPTNLHSY GSFLLSPTQV SNSCSFAPLQ  480
MPEFPLPLSL PMSLPLVGPN IVPPLGGFHF NDLPLTPNGV SSHSSIAVGD QKYIHDDNNN  540
NKNAIIVRGN EEIKNENLCD HQNGASSAVF CGQIMDNFPS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-32115388878Probable WRKY transcription factor 4
2lex_A2e-32115388878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:26025535). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535). Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535). {ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:26025535}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:15618416, PubMed:19199048). Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416). Accumulates in response to jasmonic acid (MeJA) (By similarity). {ECO:0000250|UniProtKB:Q6B6R4, ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKR5596780.0KR559678.1 Nicotiana benthamiana WRKY transcription factor (WRKY79) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016486337.10.0PREDICTED: probable WRKY transcription factor 33 isoform X2
SwissprotQ6IEQ72e-78WRK24_ORYSJ; WRKY transcription factor WRKY24
TrEMBLA0A1S4BBU20.0A0A1S4BBU2_TOBAC; probable WRKY transcription factor 33 isoform X2
STRINGXP_009598832.10.0(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G56270.15e-77WRKY DNA-binding protein 2
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang ZL, et al.
    A negative regulator encoded by a rice WRKY gene represses both abscisic acid and gibberellins signaling in aleurone cells.
    Plant Mol. Biol., 2009. 70(1-2): p. 139-51
    [PMID:19199048]
  3. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]
  4. Zhang L, et al.
    Three WRKY transcription factors additively repress abscisic acid and gibberellin signaling in aleurone cells.
    Plant Sci., 2015. 236: p. 214-22
    [PMID:26025535]