PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016477869.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 380aa    MW: 44154.6 Da    PI: 8.4972
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016477869.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H218.74.8e-067393323
                    ETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                    C+ Cg sF  + +Lk+H+++H
  XP_016477869.1 73 CEECGASFQKPAHLKQHMQSH 93
                    *******************99 PP
2zf-C2H215.93.8e-0599123123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     ++C+  +C  s++rk++L+rH+  H
  XP_016477869.1  99 FVCHidNCQSSYRRKDHLTRHLLQH 123
                     89*******************9887 PP
3zf-C2H214.30.00012128153123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     ++Cp   C++ Fs + n++rH +  H
  XP_016477869.1 128 FECPvdGCKRAFSIQGNMTRHVKEmH 153
                     89********************9988 PP
4zf-C2H216.13.2e-05167191123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     y+C+   Cgk F+  s Lk+H  +H
  XP_016477869.1 167 YVCSepRCGKGFKFASKLKKHEDSH 191
                     89*99****************9888 PP
5zf-C2H218.45.8e-06258282223
                     EET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                     kC+  dC  +Fs+ksnL +H +  H
  XP_016477869.1 258 KCEfqDCQHTFSTKSNLIQHVKAvH 282
                     79999***************99877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355392447IPR015880Zinc finger, C2H2-like
SuperFamilySSF576673.61E-1069123No hitNo description
PROSITE profilePS5015713.5887198IPR007087Zinc finger, C2H2
SMARTSM003550.00587193IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002807393IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.607.3E-97398IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.28699128IPR007087Zinc finger, C2H2
SMARTSM003550.06999123IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.4E-1099125IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280101123IPR007087Zinc finger, C2H2
SuperFamilySSF576671.84E-6109153No hitNo description
Gene3DG3DSA:3.30.160.603.3E-5126154IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.221128158IPR007087Zinc finger, C2H2
SMARTSM003550.0014128153IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280130153IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.1E-7162191IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576679.19E-5165191No hitNo description
PROSITE profilePS5015711.385167196IPR007087Zinc finger, C2H2
SMARTSM003550.59167191IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280169191IPR007087Zinc finger, C2H2
SMARTSM003558.8199224IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280201224IPR007087Zinc finger, C2H2
SMARTSM0035513227248IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.0E-10239295No hitNo description
PROSITE profilePS5015713.547257287IPR007087Zinc finger, C2H2
SMARTSM003550.0011257282IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.4E-6258284IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280259282IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.4E-5285310IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM0035512288314IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280290314IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 380 aa     Download sequence    Send to blast
MAVKILGEMG EEKREVIFRD IRRYYCEFCG ICRSKKSLIS SHILSNHHDE MERRKDEANE  60
DVKRKEGPKM NICEECGASF QKPAHLKQHM QSHSLERPFV CHIDNCQSSY RRKDHLTRHL  120
LQHQGKLFEC PVDGCKRAFS IQGNMTRHVK EMHDQRASPE ANLPKQYVCS EPRCGKGFKF  180
ASKLKKHEDS HVKLETMEAL CLEPGCMKHF TNEKCLKEHI ESCHQHIVCE ICGTKQLKKN  240
IKRHLRTHEE ESTSERIKCE FQDCQHTFST KSNLIQHVKA VHLGDKPFSC GIAGCGMRFA  300
FKHVRDRHEK SGCHVYTPGD FVEADEQFRS RPRGGRKRKL PVFEAIMRKR ITPPCGTDPV  360
FYQGSEYLSW LLSAESDEEL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A4e-187521919155PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D4e-187521919155PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1330338RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKX0986000.0KX098600.1 Nicotiana benthamiana transcription factor IIIA 9ZF mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009804392.10.0PREDICTED: Krueppel-related zinc finger protein 1-like isoform X2
RefseqXP_016477869.10.0PREDICTED: transcription factor IIIA-like isoform X2
SwissprotQ84MZ41e-139TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A1S4AMJ80.0A0A1S4AMJ8_TOBAC; transcription factor IIIA-like isoform X2
TrEMBLA0A1U7YJY40.0A0A1U7YJY4_NICSY; Krueppel-related zinc finger protein 1-like isoform X2
STRINGXP_009804391.10.0(Nicotiana sylvestris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-134transcription factor IIIA