PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016472209.1
Common NameREV
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family HD-ZIP
Protein Properties Length: 838aa    MW: 92102.9 Da    PI: 6.1519
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016472209.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox57.42.5e-182583357
                    --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
        Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                    k  ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  XP_016472209.1 25 KYVRYTAEQVEALERVYAECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 83
                    56789****************************************************97 PP
2START156.91.6e-491643712205
                     HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT.EEEEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg.galqlmv 95 
                     +aee+++e+++ka+ ++  Wv ++ +++g++++ +f+ s+++sg a+ra+g+v  +++   +e+l+d++ W ++++ +e+    s g g+++l +
  XP_016472209.1 164 IAEETLAEFLSKATGTAVDWVPMPGMKPGPDSVGIFAISHSCSGVAARACGLVSLEPT-KIAEILKDRPSWFRDCRNVEVFTMFSAGnGTIELLY 257
                     7899******************************************************.7777777777************************** PP

                     EXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHH CS
           START  96 aelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvk 186
                     ++ +a+++l+p Rdf+++Ry+ +l+ g++v++++S++ +   p+    s++vRa++lpSg+li+p+++g+s +++v+h +l++++ +++lr+l++
  XP_016472209.1 258 TQIYAPTTLAPaRDFWTLRYTTTLENGSFVVCERSLSGTGAGPNaasASQFVRAQMLPSGYLIRPCDGGGSIIHIVDHLNLEAWSAPEILRPLYE 352
                     ****************************************999999999********************************************** PP

                     HHHHHHHHHHHHHTXXXXX CS
           START 187 sglaegaktwvatlqrqce 205
                     s+ + ++k++ a+l++ ++
  XP_016472209.1 353 SSKVVAQKMTIAALRYARQ 371
                     **************99875 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.4182084IPR001356Homeobox domain
SuperFamilySSF466891.8E-162186IPR009057Homeodomain-like
SMARTSM003891.0E-152288IPR001356Homeobox domain
CDDcd000864.75E-162585No hitNo description
PfamPF000466.5E-162683IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.9E-182783IPR009057Homeodomain-like
CDDcd146864.84E-677116No hitNo description
PROSITE profilePS5084827.323154381IPR002913START domain
CDDcd088751.85E-70158373No hitNo description
SuperFamilySSF559613.71E-34163374No hitNo description
Gene3DG3DSA:3.30.530.202.6E-20163366IPR023393START-like domain
SMARTSM002341.2E-39163372IPR002913START domain
PfamPF018527.7E-47164371IPR002913START domain
SuperFamilySSF559612.42E-5402494No hitNo description
SuperFamilySSF559612.42E-5525592No hitNo description
PfamPF086701.1E-49695837IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0009956Biological Processradial pattern formation
GO:0010014Biological Processmeristem initiation
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 838 aa     Download sequence    Send to blast
MAMVVQQHRE SSSGSITKHL DSSGKYVRYT AEQVEALERV YAECPKPSSL RRQQLIRECP  60
ILSNIEPKQI KVWFQNRRCR EKQRKESSRL QTVNRKLSAM NKLLMEENDR LQKQVSQLVC  120
ENGFMRQQLH TASAATTDVS CESVVTTPQH SLRDANNPAG LLSIAEETLA EFLSKATGTA  180
VDWVPMPGMK PGPDSVGIFA ISHSCSGVAA RACGLVSLEP TKIAEILKDR PSWFRDCRNV  240
EVFTMFSAGN GTIELLYTQI YAPTTLAPAR DFWTLRYTTT LENGSFVVCE RSLSGTGAGP  300
NAASASQFVR AQMLPSGYLI RPCDGGGSII HIVDHLNLEA WSAPEILRPL YESSKVVAQK  360
MTIAALRYAR QIAQETSGEV VYGLGRQPAV LRTFSQRLSR GFNDAINGFS DDGWSLLSSD  420
GGEDVIVAVN SRKNIATTSV PLSPLGGILC AKASMLLQNV PPVVLVRFLR EHRSEWADFN  480
VDAYVASSMK SCSYAYPGMR PTRFTGSQII MPLGHTIEHE EMLEVIRLEG HSIGQEDTFM  540
PRDVHLLQMC SGTDENAVGA CSELVFAAID EMFPDDAPLL PSGFRIIPLE SKSSDPQDTS  600
NAHRTLDLAS SLEVGPATNP ATGDVVSGYS ARSVLTIAFQ FPFEDNLQDN VATMARQYVR  660
SVVSSVQRVA MAISPAGVNS TFGSKLSPGS PEAVTLSHWI CQSYSYHMGT ELLQTDSRGD  720
ESVLKNLWQH QDAILCCSLK SLPVFIFANK AGLDMLETTL VALQDITLDK IFDESGRKVL  780
FAEFPKIMEQ GFAYLPGGIC MSAMGRHISY EQAIAWKVFA SEETVHCLAF SFINWSFV
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankJQ6869370.0JQ686937.1 Nicotiana tabacum cultivar SR1 homeobox-leucine zipper protein revoulta (REV) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016472209.10.0PREDICTED: homeobox-leucine zipper protein REVOLUTA-like
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLA0A1S4A6H80.0A0A1S4A6H8_TOBAC; homeobox-leucine zipper protein REVOLUTA-like
STRINGXP_009776589.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA45724140
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]