PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016459177.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 605aa    MW: 67395.2 Da    PI: 7.3439
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016459177.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.32.4e-12434480455
                     HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                     +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI ++q
  XP_016459177.1 434 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITEMQ 480
                     799***********************66......***************9998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.9E-5548236IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.475430479IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000833.94E-13433484No hitNo description
SuperFamilySSF474591.83E-17433492IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000107.9E-10434480IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.7E-17434491IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.5E-16436485IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 605 aa     Download sequence    Send to blast
MGTGNMSWSD EDKATVAAVL GKEAFEYLIS SSVSAECSLM AIGNDQNLQN KLSELVERPN  60
ATNFSWNYAI FWQISRSKSG ELVLGWGDGC CREPKEGEEC EVKRIFNLRL EDGAQQRMRK  120
RVLQKLHMLF GGTDEDNYAI GLDRVTDTEI FFLASMYFSF PRGEGGPGKC FGSGKHLWLS  180
DALKSPLDYC ARSFLAKSAG MQTIVLIPTD VGVVELGSVR SIPESLELLQ SIKSCFSSFL  240
VRAKQAAGIA VVTEKKDANN SPFSRSAFSE RPDGTPKIFG HDLNSGTHFR EKLAVRKAEE  300
RPWDIYPNGN RMPFMNGRNG LHAASWAQFS NVKPVKPVEL YRPQTPPAHN LQELVNGGRE  360
EFHLNNFQHQ KPARMQIDFT GATSRPIISP SHTVESEHSD VEASCKEDRV GLVDEKRPRK  420
RGRKPANGRE EPLNHVEAER QRREKLNQRF YALRAVVPNI SKMDKASLLG DAIAYITEMQ  480
KKLRDMESER ELRLGSTSRD AMAAEDGPNS EIQIRGPDIN IEAANDEVIV RVSCPLETHP  540
ISRVIQTFKE AQINVVESKL SAGNGTVFHT FVLKSSGSEQ LTKEKLLAAL SSESDSLRQF  600
SPVGQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A9e-29428490264Transcription factor MYC2
5gnj_B9e-29428490264Transcription factor MYC2
5gnj_E9e-29428490264Transcription factor MYC2
5gnj_F9e-29428490264Transcription factor MYC2
5gnj_G9e-29428490264Transcription factor MYC2
5gnj_I9e-29428490264Transcription factor MYC2
5gnj_M9e-29428490264Transcription factor MYC2
5gnj_N9e-29428490264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1415423KRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754400.0HG975440.1 Solanum pennellii chromosome ch01, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016459177.10.0PREDICTED: transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A1S3Z4N70.0A0A1S3Z4N7_TOBAC; transcription factor bHLH13-like
STRINGXP_009781532.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35852348
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]