PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016435771.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family MIKC_MADS
Protein Properties Length: 207aa    MW: 23589.8 Da    PI: 6.8006
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016435771.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF90.77.6e-29959151
                    S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
          SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                    krie+ks rqvtfskRr+g+lKKA+ELS+LCda+vav++fs++g+ly++ss
  XP_016435771.1  9 KRIEDKSSRQVTFSKRRKGLLKKAKELSILCDADVAVVVFSNRGRLYDFSS 59
                    79***********************************************96 PP
2K-box50.11.2e-17791701199
           K-box  11 eakaeslqqelak...LkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkkle 99 
                     e+ +e l++e++k        e Lq+  R+l    +++Ls+ +L +Le+qL+++l + Rs K++l++e+i+ l++kek l+eenk L+++++
  XP_016435771.1  79 ESSTEVLDTEHSKyssFMTVGELLQTVERQLEEPAVDDLSVTDLVHLEDQLQTALMQARSSKTHLMIESIKSLREKEKLLSEENKHLENQIA 170
                     44444455554441115566789*****************************************************************9986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004321.4E-38160IPR002100Transcription factor, MADS-box
PROSITE profilePS5006631.665161IPR002100Transcription factor, MADS-box
SuperFamilySSF554551.83E-30279IPR002100Transcription factor, MADS-box
CDDcd002651.36E-35273No hitNo description
PRINTSPR004045.1E-28323IPR002100Transcription factor, MADS-box
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PfamPF003191.3E-261057IPR002100Transcription factor, MADS-box
PRINTSPR004045.1E-282338IPR002100Transcription factor, MADS-box
PRINTSPR004045.1E-283859IPR002100Transcription factor, MADS-box
PROSITE profilePS5129711.20785175IPR002487Transcription factor, K-box
PfamPF014861.7E-1393169IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009910Biological Processnegative regulation of flower development
GO:0010048Biological Processvernalization response
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 207 aa     Download sequence    Send to blast
MGRKKVEIKR IEDKSSRQVT FSKRRKGLLK KAKELSILCD ADVAVVVFSN RGRLYDFSST  60
NSLTEIVQQY HSHVEAEKES STEVLDTEHS KYSSFMTVGE LLQTVERQLE EPAVDDLSVT  120
DLVHLEDQLQ TALMQARSSK THLMIESIKS LREKEKLLSE ENKHLENQIA TTKNEREVTN  180
GTMALDFTNL APASMNCRQQ KATLNFL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tqe_P4e-21187187Myocyte-specific enhancer factor 2B
1tqe_Q4e-21187187Myocyte-specific enhancer factor 2B
1tqe_R4e-21187187Myocyte-specific enhancer factor 2B
1tqe_S4e-21187187Myocyte-specific enhancer factor 2B
6c9l_A4e-21187187Myocyte-specific enhancer factor 2B
6c9l_B4e-21187187Myocyte-specific enhancer factor 2B
6c9l_C4e-21187187Myocyte-specific enhancer factor 2B
6c9l_D4e-21187187Myocyte-specific enhancer factor 2B
6c9l_E4e-21187187Myocyte-specific enhancer factor 2B
6c9l_F4e-21187187Myocyte-specific enhancer factor 2B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the negative regulation of flowering time, probably through the photoperiodic and vernalization pathways; more efficient in cv. Landsberg erecta than in cv. Columbia background. Prevents premature flowering (PubMed:12724541, PubMed:25339407). Involved in the modulation of vernalization impact on flowering according to genotype acclimation to altitude (PubMed:25339407). {ECO:0000269|PubMed:12724541, ECO:0000269|PubMed:25339407}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed during vernalization (PubMed:12724541). Regulated by HAM1 and HAM2 via epigenetic modification of chromatins at H4K5 acetylation during flowering (PubMed:23273925). {ECO:0000269|PubMed:12724541, ECO:0000269|PubMed:23273925}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009795052.11e-150PREDICTED: agamous-like MADS-box protein AGL27 isoform X1
RefseqXP_016435771.11e-150PREDICTED: agamous-like MADS-box protein AGL27 isoform X1
SwissprotQ9LSR77e-49AGL70_ARATH; Agamous-like MADS-box protein AGL70
TrEMBLA0A1S3X7B11e-149A0A1S3X7B1_TOBAC; agamous-like MADS-box protein AGL27 isoform X1
TrEMBLA0A1U7XSL91e-149A0A1U7XSL9_NICSY; agamous-like MADS-box protein AGL27 isoform X1
STRINGXP_009795052.11e-150(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA4024625
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G65050.24e-42AGAMOUS-like 31
Publications ? help Back to Top
  1. Conte MG,Gaillard S,Droc G,Perin C
    Phylogenomics of plant genomes: a methodology for genome-wide searches for orthologs in plants.
    BMC Genomics, 2008. 9: p. 183
    [PMID:18426584]
  2. Suter L,Rüegg M,Zemp N,Hennig L,Widmer A
    Gene regulatory variation mediates flowering responses to vernalization along an altitudinal gradient in Arabidopsis.
    Plant Physiol., 2014. 166(4): p. 1928-42
    [PMID:25339407]
  3. Nasim Z,Fahim M,Ahn JH
    Possible Role of MADS AFFECTING FLOWERING 3 and B-BOX DOMAIN PROTEIN 19 in Flowering Time Regulation of Arabidopsis Mutants with Defects in Nonsense-Mediated mRNA Decay.
    Front Plant Sci, 2017. 8: p. 191
    [PMID:28261246]