PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Niben101Scf15224g00002.1

Organism

Nicotiana benthamiana

Taxonomic ID

4100

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 643aa MW: 70077.8 Da PI: 5.2572

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf15224g00002.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	35.2	2.2e-11	471	516	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ +I++L Niben101Scf15224g00002.1 471 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAIAFINEL 516 799*********************6.....5*************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	1.2E-53	67	244	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	16.539	467	516	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.34E-14	470	521	No hit	No description
SuperFamily	SSF47459	1.7E-17	470	540	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	6.3E-9	471	516	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.7E-18	471	537	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.0E-15	473	522	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009269	Biological Process	response to desiccation
GO:0009611	Biological Process	response to wounding
GO:0009737	Biological Process	response to abscisic acid
GO:0009867	Biological Process	jasmonic acid mediated signaling pathway
GO:0009963	Biological Process	positive regulation of flavonoid biosynthetic process
GO:0010200	Biological Process	response to chitin
GO:0043619	Biological Process	regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0051090	Biological Process	regulation of sequence-specific DNA binding transcription factor activity
GO:2000068	Biological Process	regulation of defense response to insect
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 643 aa Download sequence Send to blast
MTNIWSNTTS DDNMMEAFLS SDPSSFWPGT TTTTPTPRSS VSPAPAPVTG IAVDPLTSMP 60 YFNQESLQQR LQTLIDGARE AWTYAIFWQS PSVLGWGDGY YKGEEDKNKR KTASLSPDFI 120 TEQAHRKKVL RELNSLISGT QTGGENDAVD EEVTDTEWFF LISMTQSFVN GSGLPGLAMY 180 SSSPIWVTGA ERLAASHCER ARQAQGFGLQ TIVCIPSANG VVELGSTELI FQTADLMNKV 240 KVLFNFNIDM GATTGSGSGS CAIQAEPDPS ALWLTDPASS VAEVKDSANT IPSSNSSKQL 300 VFGNENSENG HQNSQQTQGF FTRELNFSEY GFDGSNTRNG NANSSRSCKP ESGEILNFGD 360 STKRSVSSAN GSLFSGQSQF GAGPAEENKN KNKKRSSASR GSNDEGMLSF VSGVILPSSN 420 TGKSSGGGDS DQSDLEASVV KEADSSRVVD PEKKPRKRGR KPANGREEPL NHVEAERQRR 480 EKLNQRFYAL RAVVPNVSKM DKASLLGDAI AFINELKSKV QNSDSDKEEL RNQIESLRKE 540 LANKGSNYTG PPPSNQELKI VDMDIDVKVI GWDAMIRIQS NKKNHPAARL MAALMELDLD 600 VHHASVSVVN ELMIQQATVK MESRLYTQEQ LRISLTSRIA ESR

Sequence ? help Back to Top

Protein Sequence Length: 643 aa Download sequence Send to blast

MTNIWSNTTS DDNMMEAFLS SDPSSFWPGT TTTTPTPRSS VSPAPAPVTG IAVDPLTSMP  60
YFNQESLQQR LQTLIDGARE AWTYAIFWQS PSVLGWGDGY YKGEEDKNKR KTASLSPDFI  120
TEQAHRKKVL RELNSLISGT QTGGENDAVD EEVTDTEWFF LISMTQSFVN GSGLPGLAMY  180
SSSPIWVTGA ERLAASHCER ARQAQGFGLQ TIVCIPSANG VVELGSTELI FQTADLMNKV  240
KVLFNFNIDM GATTGSGSGS CAIQAEPDPS ALWLTDPASS VAEVKDSANT IPSSNSSKQL  300
VFGNENSENG HQNSQQTQGF FTRELNFSEY GFDGSNTRNG NANSSRSCKP ESGEILNFGD  360
STKRSVSSAN GSLFSGQSQF GAGPAEENKN KNKKRSSASR GSNDEGMLSF VSGVILPSSN  420
TGKSSGGGDS DQSDLEASVV KEADSSRVVD PEKKPRKRGR KPANGREEPL NHVEAERQRR  480
EKLNQRFYAL RAVVPNVSKM DKASLLGDAI AFINELKSKV QNSDSDKEEL RNQIESLRKE  540
LANKGSNYTG PPPSNQELKI VDMDIDVKVI GWDAMIRIQS NKKNHPAARL MAALMELDLD  600
VHHASVSVVN ELMIQQATVK MESRLYTQEQ LRISLTSRIA ESR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	6e-65	60	247	2	195	Transcription factor MYC3
4rqw_B	6e-65	60	247	2	195	Transcription factor MYC3
4rs9_A	6e-65	60	247	2	195	Transcription factor MYC3
4yz6_A	6e-65	60	247	2	195	Transcription factor MYC3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	452	460	KKPRKRGRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in a number of promoters of jasmonate-induced genes (PubMed:15231736). Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371, PubMed:30518626). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). Acts synergistically with EOT1 in the transactivation of TPS5 (PubMed:24884371). Involved in type VI glandular trichome development (PubMed:30518626). Involved in the activation of terpene synthases required for volatile mono- and sesquiterpenes synthesis by the glandular cells of type VI trichomes (PubMed:30518626). {ECO:0000269\|PubMed:15231736, ECO:0000269\|PubMed:24884371, ECO:0000269\|PubMed:30518626}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00084	PBM	Transfer from AT1G32640	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by methyl jasmonate and wounding. {ECO:0000269\|PubMed:15231736}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009800420.1	0.0	PREDICTED: transcription factor MYC2-like
Swissprot	A0A060KY90	0.0	MYC1_SOLLC; Transcription factor MYC1
TrEMBL	D7P229	0.0	D7P229_NICBE; BHLH2 transcription factor
STRING	XP_009800420.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3300	24	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G32640.1	0.0	bHLH family protein

Publications ? help Back to Top
Todd AT,Liu E,Polvi SL,Pammett RT,Page JE A functional genomics screen identifies diverse transcription factors that regulate alkaloid biosynthesis in Nicotiana benthamiana. Plant J., 2010. 62(4): p. 589-600 [PMID:20202168] Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371] Xu J, et al. SlMYC1 Regulates Type VI Glandular Trichome Formation and Terpene Biosynthesis in Tomato Glandular Cells. Plant Cell, 2018. 30(12): p. 2988-3005 [PMID:30518626]