PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr6g071625.1

Common Name

MTR_6g071625

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

G2-like

Protein Properties

Length: 369aa MW: 41580.9 Da PI: 7.7603

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr6g071625.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	102.3	3e-32	203	256	2	55
G2-like 2 prlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 pr+rWt+ LH+rFv+ave LGG+e+AtPk++lelm+vk+Ltl+hvkSHLQ+YR+ Medtr6g071625.1 203 PRMRWTSSLHNRFVHAVELLGGHERATPKSVLELMDVKDLTLAHVKSHLQMYRT 256 9****************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	9.5E-16	200	257	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	5.9E-29	201	257	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	5.4E-24	203	256	IPR006447	Myb domain, plants
Pfam	PF00249	2.5E-7	204	255	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 369 aa Download sequence Send to blast
MPQNQIPDLS LQISLPNSSQ TSICTTNEVD DLDSSFDIWK NINDAITHEG FKSHSDGFSS 60 SIRNSTLQKT DTELSLSNSK TKTTTFSEAE SVWKRKNFVR LRPFNGIPLY SDNNPSIIEK 120 DSNSSLYPSC SASSSTFSRF NGITIESLRP QKFQYMNHQH HLLQNQQQQK VNQFGNSEFG 180 NGFVRSRMMM PRQQSNKRNM RAPRMRWTSS LHNRFVHAVE LLGGHERATP KSVLELMDVK 240 DLTLAHVKSH LQMYRTVKNT DKPAASSDGD ENFMSLTQPH DQNKNYNASL EHDIGYTSNT 300 LWANSSSSNG TWTQGSSGDH FEELSTQEIL STHHIGKLPQ GSNCIQSRSS KDQNIDCPNP 360 NLEFTLGR*

Sequence ? help Back to Top

Protein Sequence Length: 369 aa Download sequence Send to blast

MPQNQIPDLS LQISLPNSSQ TSICTTNEVD DLDSSFDIWK NINDAITHEG FKSHSDGFSS  60
SIRNSTLQKT DTELSLSNSK TKTTTFSEAE SVWKRKNFVR LRPFNGIPLY SDNNPSIIEK  120
DSNSSLYPSC SASSSTFSRF NGITIESLRP QKFQYMNHQH HLLQNQQQQK VNQFGNSEFG  180
NGFVRSRMMM PRQQSNKRNM RAPRMRWTSS LHNRFVHAVE LLGGHERATP KSVLELMDVK  240
DLTLAHVKSH LQMYRTVKNT DKPAASSDGD ENFMSLTQPH DQNKNYNASL EHDIGYTSNT  300
LWANSSSSNG TWTQGSSGDH FEELSTQEIL STHHIGKLPQ GSNCIQSRSS KDQNIDCPNP  360
NLEFTLGR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6j4k_A	9e-18	204	258	4	58	Protein PHOSPHATE STARVATION RESPONSE 1
6j4k_B	9e-18	204	258	4	58	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_A	9e-18	204	258	4	58	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_C	9e-18	204	258	4	58	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_D	9e-18	204	258	4	58	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_F	9e-18	204	258	4	58	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_H	9e-18	204	258	4	58	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_J	9e-18	204	258	4	58	Protein PHOSPHATE STARVATION RESPONSE 1
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: In globular embryos, expressed in the peripheral cells in a basal region above the hypophysis. In heart-stage embryos, expressed in the periphery of the presumptive hypocotyl and on the abaxial side of cotyledon primordia. During vegetative growth, expressed the abaxial side of very young leaf primordia. Expressed on the abaxial side of carpel primordia and then in a localized region on the abaxial margin that gives rise to the septum. Later, expressed in the tissue that gives rise to ovules. {ECO:0000269\|PubMed:11525739}.
Uniprot	TISSUE SPECIFICITY: Expressed in developing phloem and lateral root. {ECO:0000269\|PubMed:11525739, ECO:0000269\|PubMed:14561401, ECO:0000269\|PubMed:15286295}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that regulates lateral organ polarity. Promotes lateral organ abaxial identity by repressing the adaxial regulator ASYMMETRIC LEAVES2 (AS2) in abaxial cells. Required for abaxial identity in both leaves and carpels. Functions with KAN2 in the specification of polarity of the ovule outer integument. Regulates cambium activity by repressing the auxin efflux carrier PIN1. Plays a role in lateral root formation and development. {ECO:0000269\|PubMed:11395775, ECO:0000269\|PubMed:11525739, ECO:0000269\|PubMed:14561401, ECO:0000269\|PubMed:15286295, ECO:0000269\|PubMed:16623911, ECO:0000269\|PubMed:17307928, ECO:0000269\|PubMed:18849474, ECO:0000269\|PubMed:20179097}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr6g071625.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by AS2 in adaxial tissue. {ECO:0000269\|PubMed:18849474}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013452731.1	0.0	probable transcription factor KAN4
Swissprot	Q93WJ9	9e-47	KAN1_ARATH; Transcription repressor KAN1
TrEMBL	A0A072UAE1	0.0	A0A072UAE1_MEDTR; Myb-like DNA-binding domain, shaqkyf class protein
STRING	XP_004513340.1	1e-161	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1756	33	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G16560.1	4e-49	G2-like family protein

Link Out ? help Back to Top
Phytozome	Medtr6g071625.1
Entrez Gene	25496643

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Huang T,Kerstetter RA,Irish VF APUM23, a PUF family protein, functions in leaf development and organ polarity in Arabidopsis. J. Exp. Bot., 2014. 65(4): p. 1181-91 [PMID:24449383] Mach J Getting in Shape? Leaves work it out with KANADI1. Plant Cell, 2014. 26(1): p. 4 [PMID:24464293] Jun SE, et al. Comparative analysis of the conserved functions of Arabidopsis DRL1 and yeast KTI12. Mol. Cells, 2015. 38(3): p. 243-50 [PMID:25518926] Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis. Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71 [PMID:26108442] Xie Y, et al. Meta-Analysis of Arabidopsis KANADI1 Direct Target Genes Identifies a Basic Growth-Promoting Module Acting Upstream of Hormonal Signaling Pathways. Plant Physiol., 2015. 169(2): p. 1240-53 [PMID:26246448] Alvarez JP,Furumizu C,Efroni I,Eshed Y,Bowman JL Active suppression of a leaf meristem orchestrates determinate leaf growth. Elife, 2017. [PMID:27710768] Singh A, et al. Phytohormonal crosstalk modulates the expression of miR166/165s, target Class III HD-ZIPs, and KANADI genes during root growth in Arabidopsis thaliana. Sci Rep, 2017. 7(1): p. 3408 [PMID:28611467] Caggiano MP, et al. Cell type boundaries organize plant development. Elife, 2018. [PMID:28895530] Ó'Maoiléidigh DS,Stewart D,Zheng B,Coupland G,Wellmer F Floral homeotic proteins modulate the genetic program for leaf development to suppress trichome formation in flowers. Development, 2018. [PMID:29361563]