PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr2g099010.1

Common Name

MTR_2g099010

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

DBB

Protein Properties

Length: 244aa MW: 27430.7 Da PI: 4.5709

Description

DBB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr2g099010.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-B_box	20.1	1.3e-06	4	44	5	39
zf-B_box 5 kCpeHeekelqlfCedCqqllCedClleeHkg......Htv 39 C+ +e+ +++ C ++ lC++C e H H++ Medtr2g099010.1 4 QCDVCEKAPATMICCADEAALCAKCDIEVHAAnklaskHQR 44 7*****************************65677777765 PP
2	zf-B_box	29.1	2.1e-09	53	85	2	34
zf-B_box 2 eerkCpeHeekelqlfCedCqqllCedClleeH 34 + ++C+ +++k + +fC +++ l+CedC +++H Medtr2g099010.1 53 KLPRCDICQDKTAFIFCVEDRALFCEDCDESIH 85 789*****************************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50119	9.414	1	47	IPR000315	B-box-type zinc finger
CDD	cd00021	8.29E-6	3	44	No hit	No description
SMART	SM00336	4.5E-8	4	47	IPR000315	B-box-type zinc finger
PROSITE profile	PS50119	9.428	52	99	IPR000315	B-box-type zinc finger
SMART	SM00336	1.5E-14	52	99	IPR000315	B-box-type zinc finger
Pfam	PF00643	1.1E-7	53	94	IPR000315	B-box-type zinc finger
CDD	cd00021	4.04E-7	55	98	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005622	Cellular Component	intracellular
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 244 aa Download sequence Send to blast
MKIQCDVCEK APATMICCAD EAALCAKCDI EVHAANKLAS KHQRIHLQSL SNKLPRCDIC 60 QDKTAFIFCV EDRALFCEDC DESIHLPGSL SANHQRFLAT GIQVAMKSNC AKDDEKTHLE 120 PPKRSTHQVS LETTSQQVPD FTPPWGVDDL LELADFNSHD KKDSMQFGEM EWFTEEGLFG 180 DDFTQEAMAA AEVPQLPVTH ASNNYSSYRN SKSHMSNKKP RIELIRDYDY DDEDEYFTVP 240 DLG*

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.15663	0.0	flower\| leaf\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: High expression in leaves and lower in roots and flowers.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of seedling photomorphogenesis and light-regulated inhibition of hypocotyl elongation (PubMed:17605755, PubMed:18540109, PubMed:21685177). BBX24/STO and BBX25/STH function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression. BBX24/STO acts additively with BBX25/STH during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715). Functions as negative regulator of photomorphogenic UV-B responses by interacting with both COP1 and HY5 (PubMed:22410790). May act as a transcription factor in the salt-stress response (PubMed:12909688). {ECO:0000269\|PubMed:12909688, ECO:0000269\|PubMed:17605755, ECO:0000269\|PubMed:18540109, ECO:0000269\|PubMed:21685177, ECO:0000269\|PubMed:22410790, ECO:0000269\|PubMed:23624715}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr2g099010.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian regulation with a peak before dawn. {ECO:0000269\|PubMed:17605755}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT144426	0.0	BT144426.1 Medicago truncatula clone JCVI-FLMt-5I24 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003597525.1	0.0	B-box zinc finger protein 24 isoform X1
Swissprot	Q96288	5e-93	BBX24_ARATH; B-box zinc finger protein 24
TrEMBL	G7IHV4	0.0	G7IHV4_MEDTR; Putative transcription factor interactor and regulator Znf-B family
STRING	AES67776	0.0	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3438	31	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G06040.1	5e-86	DBB family protein

Link Out ? help Back to Top
Phytozome	Medtr2g099010.1
Entrez Gene	11431876

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Gangappa SN,Holm M,Botto JF Molecular interactions of BBX24 and BBX25 with HYH, HY5 HOMOLOG, to modulate Arabidopsis seedling development. Plant Signal Behav, 2014. [PMID:23733077] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Imtiaz M, et al. Identification and functional characterization of the BBX24 promoter and gene from chrysanthemum in Arabidopsis. Plant Mol. Biol., 2015. 89(1-2): p. 1-19 [PMID:26253592] Job N,Yadukrishnan P,Bursch K,Datta S,Johansson H Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains. Plant Physiol., 2018. 176(4): p. 2963-2976 [PMID:29439209]