PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr2g008840.2
Common NameMTR_2g008840
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family CAMTA
Protein Properties Length: 899aa    MW: 100124 Da    PI: 5.5199
Description CAMTA family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr2g008840.2genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1CG-1179.83.3e-56221354118
             CG-1   4 ekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrr 97 
                       ++rwl++ ei++iL n++ +++t e++trp+sgsl+L++rk++ryfrkDG++w+kkkdgktv+E+hekLKvg+v++l+cyYah+een++fqrr
  Medtr2g008840.2  22 AQHRWLRPAEICEILRNYRMFHITPEPHTRPPSGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHEKLKVGSVDALHCYYAHGEENENFQRR 115
                      49******************************************************************************************** PP

             CG-1  98 cywlLeeelekivlvhylevk 118
                      +ywlLe++ ++iv+vhylevk
  Medtr2g008840.2 116 SYWLLEQD-THIVFVHYLEVK 135
                      ********.*********985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5143779.93315140IPR005559CG-1 DNA-binding domain
SMARTSM010762.6E-7618135IPR005559CG-1 DNA-binding domain
PfamPF038595.5E-5121134IPR005559CG-1 DNA-binding domain
PfamPF018337.3E-8453529IPR002909IPT domain
CDDcd001020.00389453541No hitNo description
Gene3DG3DSA:2.60.40.103.5E-6454533IPR013783Immunoglobulin-like fold
SuperFamilySSF812969.94E-18454539IPR014756Immunoglobulin E-set
SuperFamilySSF484032.33E-19629748IPR020683Ankyrin repeat-containing domain
PfamPF127962.6E-8636715IPR020683Ankyrin repeat-containing domain
PROSITE profilePS5029720.022637758IPR020683Ankyrin repeat-containing domain
Gene3DG3DSA:1.25.40.202.0E-19642749IPR020683Ankyrin repeat-containing domain
CDDcd002046.65E-16643740No hitNo description
SMARTSM00248740654683IPR002110Ankyrin repeat
PROSITE profilePS500889.19654686IPR002110Ankyrin repeat
SMARTSM002480.002687716IPR002110Ankyrin repeat
PROSITE profilePS5008810.018687719IPR002110Ankyrin repeat
SMARTSM002482300726755IPR002110Ankyrin repeat
PROSITE profilePS500968.023866894IPR000048IQ motif, EF-hand binding site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009409Biological Processresponse to cold
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0071275Biological Processcellular response to aluminum ion
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 899 aa     Download sequence    Send to blast
MAEPPSFGLG PRLDIQQLQF EAQHRWLRPA EICEILRNYR MFHITPEPHT RPPSGSLFLF  60
DRKVLRYFRK DGHNWRKKKD GKTVKEAHEK LKVGSVDALH CYYAHGEENE NFQRRSYWLL  120
EQDTHIVFVH YLEVKSNKSN IGGNADSNEV ISDSQKVNSP SSGIPATYSS VPSLSTDSMS  180
PTSSYTSLRE DADSGDHGQS SVSGMDYIPP FSRDTFRGNG ATCIDGQASW DTVLQSTAEL  240
HADPSLVSFT SIPSGSLSNI LDQEDNILGD FSMSRSGLAI GAGSSQPLQS NWQIPFEDNT  300
GHMPTFTQSL SLEFASDYGT GLLGNESDNG SSIIDPVLFS FHGEPKEKLA QQNYLEEKVD  360
GHPRDDLKSN STKEVPSEET INYPLPVRRT LLDRDESLRK VDSFNRWITK ALGEVDDLNM  420
QSSPGISWSA DDCGHVIDDT SLSPSLSQDQ LYSITDFSPK WAYAESDTEV LIIGSFLKSQ  480
PDVTACNWSC MFGEVEVPAE VVANGILCCQ APPHKVGRVP FYVTCANRLA CSEVREFDFR  540
DGYSRNVDYT DFFNSSNDML LHLRLEEFLS LKPVHPSNQT FEGDTEKRSL ILKLISLREE  600
EEYSSKEEQT VEMDISRHKV KKHLFHRQFK EKLYSWLLHK VTESGKGPNV LDKDGQGVLH  660
LAAGLGYDWA IILILAAGVN INFRDVNGWT ALHWAASCGR ERTVGALVHM GADCGALTDP  720
SPEFPSGRTA ADLASSNGNK GLSGFLAESS LTSHLESLTV DDLHKGGQQE VSRTKAVQTV  780
SERTATPVIY NDMPDALCLK DSLTAVRNAT QAADRIHQVF RMQSFQRKQL TQDEDDDDEF  840
GLLDQRALSL LASKARKSGQ GDGLVNAAAT QIQKKFRGWK KRKEFLLIRQ RIVKIQVQ*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6mog_A2e-1264374665162DARPin C_R3
6mog_B2e-1264374665162DARPin C_R3
6moh_A2e-1264374665162Dimeric DARPin E2C (C_R3)
6moh_B2e-1264374665162Dimeric DARPin E2C (C_R3)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.82660.0leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, stems, old leaves, petals, sepals, top of carpels, stigmas, stamen filaments, anthers and siliques, but not in pollen. {ECO:0000269|PubMed:12218065, ECO:0000269|PubMed:14581622}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity). Regulates transcriptional activity in response to calcium signals (Probable). Binds calmodulin in a calcium-dependent manner (By similarity). Involved in freezing tolerance in association with CAMTA1 and CAMTA3. Contributes together with CAMTA1 and CAMTA3 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:23581962). Involved together with CAMTA3 and CAMTA4 in the positive regulation of a general stress response (PubMed:25039701). Involved in tolerance to aluminum. Binds to the promoter of ALMT1 transporter and contributes to the positive regulation of aluminum-induced expression of ALMT1 (PubMed:25627216). {ECO:0000250|UniProtKB:Q8GSA7, ECO:0000269|PubMed:23581962, ECO:0000269|PubMed:25039701, ECO:0000269|PubMed:25627216, ECO:0000305|PubMed:11925432}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00043PBMTransfer from AT5G64220Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr2g008840.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salt, wounding, abscisic acid, H(2)O(2) and salicylic acid (PubMed:12218065). Induced by aluminum (PubMed:25627216). {ECO:0000269|PubMed:12218065, ECO:0000269|PubMed:25627216}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1874650.0AC187465.3 Medicago truncatula chromosome 2 BAC clone mth2-69g14, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003593198.20.0calmodulin-binding transcription activator 2 isoform X2
SwissprotQ6NPP40.0CMTA2_ARATH; Calmodulin-binding transcription activator 2
TrEMBLG7INW10.0G7INW1_MEDTR; Calmodulin-binding transcription activator 1
STRINGAES634490.0(Medicago truncatula)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G09410.10.0ethylene induced calmodulin binding protein
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Benn G, et al.
    A key general stress response motif is regulated non-uniformly by CAMTA transcription factors.
    Plant J., 2014. 80(1): p. 82-92
    [PMID:25039701]
  3. Kidokoro S, et al.
    Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature.
    Plant Cell, 2017. 29(4): p. 760-774
    [PMID:28351986]