PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Migut.N03147.1.p

Common Name

LOC105959573, MIMGU_mgv1a001550mg

Organism

Mimulus guttatus

Taxonomic ID

4155

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

ARF

Protein Properties

Length: 799aa MW: 89538.8 Da PI: 5.924

Description

ARF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.N03147.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	B3	77.2	1.8e-24	142	243	1	99
EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SS CS B3 1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgr 87 f+k+lt sd++++g +++p++ ae+ ++++++ ++l+++d++ ++W++++iyr++++r++lt+GW+ Fv a++L++gD+v+F ++ Migut.N03147.1.p 142 FCKTLTASDTSTHGGFSVPRRAAEKLfpqldySMQPPT-QELVVRDLHDNTWTFRHIYRGQPKRHLLTTGWSMFVGAKRLRAGDSVLFI--RD 231 99*******************999*9555554.49**********************************************..45 PP SEE..EEEEE-S CS B3 88 sefelvvkvfrk 99 ++ +l+++v+r Migut.N03147.1.p 232 EKSQLLLGVRRV 243 677789999985 PP
2	Auxin_resp	108.2	9.1e-36	268	351	1	83
Auxin_resp 1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 aahaa++k++F+++YnPra++s F+v+++k++ka++ +++s+ mRf ++fete+s +rr++Gt++g+sdldp+rWpnSkWrsL+ Migut.N03147.1.p 268 AAHAAANKTPFTIFYNPRACPSVFIVPLAKYRKAVYgTQISISMRFGFMFETEESTKRRYMGTIIGISDLDPLRWPNSKWRSLQ 351 79********************************9*******************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101936	2.49E-47	128	271	IPR015300	DNA-binding pseudobarrel domain
Gene3D	G3DSA:2.40.330.10	1.8E-41	135	256	IPR015300	DNA-binding pseudobarrel domain
CDD	cd10017	3.93E-22	141	242	No hit	No description
Pfam	PF02362	7.3E-22	142	243	IPR003340	B3 DNA binding domain
SMART	SM01019	2.4E-23	142	244	IPR003340	B3 DNA binding domain
PROSITE profile	PS50863	13.028	142	244	IPR003340	B3 DNA binding domain
Pfam	PF06507	2.3E-31	268	351	IPR010525	Auxin response factor
PROSITE profile	PS51745	24.573	698	781	IPR000270	PB1 domain
SuperFamily	SSF54277	5.1E-8	712	776	No hit	No description
Pfam	PF02309	4.3E-8	741	784	IPR033389	AUX/IAA domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009734	Biological Process	auxin-activated signaling pathway
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 799 aa Download sequence Send to blast
MGSVEEKQKA GANSNMFEGM KLLKEVHDHA GLKKPINSEL WHACAGPLVT LPQIGSLVYY 60 FPQGHSEQVA VSTNRTATTQ IPNYPNLPSQ LLCQVHNVTL HADKETDETY AQLSLQAVNS 120 EKDVFTIPDF GQKPSKHPTE FFCKTLTASD TSTHGGFSVP RRAAEKLFPQ LDYSMQPPTQ 180 ELVVRDLHDN TWTFRHIYRG QPKRHLLTTG WSMFVGAKRL RAGDSVLFIR DEKSQLLLGV 240 RRVNRQQTTL PSSVLSTDSM HIGIFAAAAH AAANKTPFTI FYNPRACPSV FIVPLAKYRK 300 AVYGTQISIS MRFGFMFETE ESTKRRYMGT IIGISDLDPL RWPNSKWRSL QVEWDEPGCG 360 DKQNRVSPWE VETPESLFIF PSLTATLKRP FHSSFIGAQT EWENLIHRPF PRFPDSPLQC 420 SSVSNMWSDQ IKKMLTSVNI PAQEETHPQI MAGQSNTAYT KFEHVLGNDF TAANQNNGML 480 HLQTSPFTTQ SSQFETHILQ TQQTEPTQIE SSSQVDFHSY RNLCSSSSPS GSCSMFKKSE 540 QSSEAVFPML TSVGQEMWDP HFNNTAKCVS EATNNLPVLL PHQEMSEIQY NSCGLNMKDL 600 SDENGGDIYS CLNIDSSNSG STVMDPSVSN TTILDDFCTL KNVDFPNHSD NYLVGNLCDV 660 QSQITSASLA DSSNVDFDEN ILLHQGSFQT QQLPPRFRTY TKIQKAGSVG RSIDVSSFKD 720 YKQLRCEIER MFGLEGLLID SCSEWKLVYV DFENDVLLVG DDPWEEFVGC VRCIRILSPS 780 EVKQMGEEGM QILNSVLS*

Sequence ? help Back to Top

Protein Sequence Length: 799 aa Download sequence Send to blast

MGSVEEKQKA GANSNMFEGM KLLKEVHDHA GLKKPINSEL WHACAGPLVT LPQIGSLVYY  60
FPQGHSEQVA VSTNRTATTQ IPNYPNLPSQ LLCQVHNVTL HADKETDETY AQLSLQAVNS  120
EKDVFTIPDF GQKPSKHPTE FFCKTLTASD TSTHGGFSVP RRAAEKLFPQ LDYSMQPPTQ  180
ELVVRDLHDN TWTFRHIYRG QPKRHLLTTG WSMFVGAKRL RAGDSVLFIR DEKSQLLLGV  240
RRVNRQQTTL PSSVLSTDSM HIGIFAAAAH AAANKTPFTI FYNPRACPSV FIVPLAKYRK  300
AVYGTQISIS MRFGFMFETE ESTKRRYMGT IIGISDLDPL RWPNSKWRSL QVEWDEPGCG  360
DKQNRVSPWE VETPESLFIF PSLTATLKRP FHSSFIGAQT EWENLIHRPF PRFPDSPLQC  420
SSVSNMWSDQ IKKMLTSVNI PAQEETHPQI MAGQSNTAYT KFEHVLGNDF TAANQNNGML  480
HLQTSPFTTQ SSQFETHILQ TQQTEPTQIE SSSQVDFHSY RNLCSSSSPS GSCSMFKKSE  540
QSSEAVFPML TSVGQEMWDP HFNNTAKCVS EATNNLPVLL PHQEMSEIQY NSCGLNMKDL  600
SDENGGDIYS CLNIDSSNSG STVMDPSVSN TTILDDFCTL KNVDFPNHSD NYLVGNLCDV  660
QSQITSASLA DSSNVDFDEN ILLHQGSFQT QQLPPRFRTY TKIQKAGSVG RSIDVSSFKD  720
YKQLRCEIER MFGLEGLLID SCSEWKLVYV DFENDVLLVG DDPWEEFVGC VRCIRILSPS  780
EVKQMGEEGM QILNSVLS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ldu_A	0.0	12	376	29	392	Auxin response factor 5
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity. {ECO:0000269\|PubMed:12036261, ECO:0000269\|PubMed:14973283, ECO:0000269\|PubMed:17553903}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.N03147.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012839167.1	0.0	PREDICTED: auxin response factor 5-like
Swissprot	P93024	0.0	ARFE_ARATH; Auxin response factor 5
TrEMBL	A0A022R9T6	0.0	A0A022R9T6_ERYGU; Auxin response factor

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5859	23	34

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19850.1	0.0	ARF family protein

Link Out ? help Back to Top
Phytozome	Migut.N03147.1.p
Entrez Gene	105959573

Publications ? help Back to Top
Chen MK,Wilson RL,Palme K,Ditengou FA,Shpak ED ERECTA family genes regulate auxin transport in the shoot apical meristem and forming leaf primordia. Plant Physiol., 2013. 162(4): p. 1978-91 [PMID:23821653] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Qi J, et al. Auxin depletion from leaf primordia contributes to organ patterning. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(52): p. 18769-74 [PMID:25512543] Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Zhang Y, et al. Regulation of oncogene expression in T-DNA-transformed host plant cells. PLoS Pathog., 2015. 11(1): p. e1004620 [PMID:25615824] Robert HS, et al. Plant embryogenesis requires AUX/LAX-mediated auxin influx. Development, 2015. 142(4): p. 702-11 [PMID:25617434] Krogan NT,Berleth T The identification and characterization of specific ARF-Aux/IAA regulatory modules in plant growth and development. Plant Signal Behav, 2015. 10(4): p. e992748 [PMID:25830553] Ckurshumova W,Berleth T Overcoming recalcitrance - Auxin response factor functions in plant regeneration. Plant Signal Behav, 2015. 10(7): p. e993293 [PMID:26098229] Wendrich JR, et al. A set of domain-specific markers in the Arabidopsis embryo. Plant Reprod, 2015. 28(3-4): p. 153-60 [PMID:26216537] Wu MF, et al. Auxin-regulated chromatin switch directs acquisition of flower primordium founder fate. Elife, 2015. 4: p. e09269 [PMID:26460543] Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis. Plant Physiol., 2016. 170(1): p. 283-93 [PMID:26537561] Müller CJ, et al. PHABULOSA Mediates an Auxin Signaling Loop to Regulate Vascular Patterning in Arabidopsis. Plant Physiol., 2016. 170(2): p. 956-70 [PMID:26637548] Herud O,Weijers D,Lau S,Jürgens G Auxin responsiveness of the MONOPTEROS-BODENLOS module in primary root initiation critically depends on the nuclear import kinetics of the Aux/IAA inhibitor BODENLOS. Plant J., 2016. 85(2): p. 269-77 [PMID:26714008] Luo S, et al. Constitutive Expression of OsIAA9 Affects Starch Granules Accumulation and Root Gravitropic Response in Arabidopsis. Front Plant Sci, 2015. 6: p. 1156 [PMID:26734051] Yamaguchi N,Wu MF,Winter CM,Wagner D LEAFY and Polar Auxin Transport Coordinately Regulate Arabidopsis Flower Development. Plants (Basel), 2014. 3(2): p. 251-65 [PMID:27135503] Krogan NT,Marcos D,Weiner AI,Berleth T The auxin response factor MONOPTEROS controls meristem function and organogenesis in both the shoot and root through the direct regulation of PIN genes. New Phytol., 2016. 212(1): p. 42-50 [PMID:27441727] Fendrych M,Leung J,Friml J TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls. Elife, 2018. [PMID:27627746] Matthes M,Torres-Ruiz RA Boronic acid treatment phenocopies monopteros by affecting PIN1 membrane stability and polar auxin transport in Arabidopsis thaliana embryos. Development, 2016. 143(21): p. 4053-4062 [PMID:27697905] Bhatia N, et al. Auxin Acts through MONOPTEROS to Regulate Plant Cell Polarity and Pattern Phyllotaxis. Curr. Biol., 2016. 26(23): p. 3202-3208 [PMID:27818174] Wójcikowska B,Gaj MD Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis. Plant Cell Rep., 2017. 36(6): p. 843-858 [PMID:28255787] Möller BK, et al. Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(12): p. E2533-E2539 [PMID:28265057] Carey NS,Krogan NT The role of AUXIN RESPONSE FACTORs in the development and differential growth of inflorescence stems. Plant Signal Behav, 2017. 12(4): p. e1307492 [PMID:28340328] Guan C, et al. Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis. Curr. Biol., 2017. 27(19): p. 2940-2950.e4 [PMID:28943086] Gaillochet C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. Elife, 2018. [PMID:29058667] Zheng K, et al. Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis. Front Plant Sci, 2017. 8: p. 1813 [PMID:29114256] Liu Z, et al. ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis. Plant Cell Physiol., 2018. 59(1): p. 179-189 [PMID:29145642]