PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G19850.1
Common NameARF5, F6F9.10, IAA24, MP
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ARF
Protein Properties Length: 902aa    MW: 99650.3 Da    PI: 5.9295
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G19850.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B377.31.7e-24158259199
                  EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE.. CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefel 92 
                  f+k+lt sd++++g +++p++ ae+       + ++++ ++l+++d++ ++W++++iyr++++r++lt+GW+ Fv +++L++gD+v+F   ++++ +l
  AT1G19850.1 158 FCKTLTASDTSTHGGFSVPRRAAEKLfppldySAQPPT-QELVVRDLHENTWTFRHIYRGQPKRHLLTTGWSLFVGSKRLRAGDSVLFI--RDEKSQL 252
                  99*********************999*****9444444.49************************************************..4577778 PP

                  EEEEE-S CS
           B3  93 vvkvfrk 99 
                  +v+v+r+
  AT1G19850.1 253 MVGVRRA 259
                  *****97 PP
2Auxin_resp111.67.9e-37284367183
   Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                  aaha++++++F ++YnPra+++eFv++++k++ka+  +++svGmRf m+feteds +rr++Gt+vg+sdldp+rWp+SkWr+L+
  AT1G19850.1 284 AAHATANRTPFLIFYNPRACPAEFVIPLAKYRKAICgSQLSVGMRFGMMFETEDSGKRRYMGTIVGISDLDPLRWPGSKWRNLQ 367
                  79********************************9989********************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019367.72E-46148287IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.102.5E-42150272IPR015300DNA-binding pseudobarrel domain
CDDcd100176.75E-23157258No hitNo description
PfamPF023623.1E-22158259IPR003340B3 DNA binding domain
PROSITE profilePS5086313.183158260IPR003340B3 DNA binding domain
SMARTSM010199.2E-26158260IPR003340B3 DNA binding domain
PfamPF065078.9E-32284367IPR010525Auxin response factor
PfamPF023092.2E-9785879IPR033389AUX/IAA domain
PROSITE profilePS5174523.118793877IPR000270PB1 domain
SuperFamilySSF542775.1E-7807872No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009733Biological Processresponse to auxin
GO:0009734Biological Processauxin-activated signaling pathway
GO:0009908Biological Processflower development
GO:0009942Biological Processlongitudinal axis specification
GO:0010305Biological Processleaf vascular tissue pattern formation
GO:0048364Biological Processroot development
GO:0048507Biological Processmeristem development
GO:0005634Cellular Componentnucleus
GO:0016020Cellular Componentmembrane
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0042802Molecular Functionidentical protein binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 902 aa     Download sequence    Send to blast
MMASLSCVED KMKTSCLVNG GGTITTTTSQ STLLEEMKLL KDQSGTRKPV INSELWHACA  60
GPLVCLPQVG SLVYYFSQGH SEQVAVSTRR SATTQVPNYP NLPSQLMCQV HNVTLHADKD  120
SDEIYAQMSL QPVHSERDVF PVPDFGMLRG SKHPTEFFCK TLTASDTSTH GGFSVPRRAA  180
EKLFPPLDYS AQPPTQELVV RDLHENTWTF RHIYRGQPKR HLLTTGWSLF VGSKRLRAGD  240
SVLFIRDEKS QLMVGVRRAN RQQTALPSSV LSADSMHIGV LAAAAHATAN RTPFLIFYNP  300
RACPAEFVIP LAKYRKAICG SQLSVGMRFG MMFETEDSGK RRYMGTIVGI SDLDPLRWPG  360
SKWRNLQVEW DEPGCNDKPT RVSPWDIETP ESLFIFPSLT SGLKRQLHPS YFAGETEWGS  420
LIKRPLIRVP DSANGIMPYA SFPSMASEQL MKMMMRPHNN QNVPSFMSEM QQNIVMGNGG  480
LLGDMKMQQP LMMNQKSEMV QPQNKLTVNP SASNTSGQEQ NLSQSMSAPA KPENSTLSGC  540
SSGRVQHGLE QSMEQASQVT TSTVCNEEKV NQLLQKPGAS SPVQADQCLD ITHQIYQPQS  600
DPINGFSFLE TDELTSQVSS FQSLAGSYKQ PFILSSQDSS AVVLPDSTNS PLFHDVWDTQ  660
LNGLKFDQFS PLMQQDLYAS QNICMSNSTT SNILDPPLSN TVLDDFCAIK DTDFQNHPSG  720
CLVGNNNTSF AQDVQSQITS ASFADSQAFS RQDFPDNSGG TGTSSSNVDF DDCSLRQNSK  780
GSSWQKIATP RVRTYTKVQK TGSVGRSIDV TSFKDYEELK SAIECMFGLE GLLTHPQSSG  840
WKLVYVDYES DVLLVGDDPW EEFVGCVRCI RILSPTEVQQ MSEEGMKLLN SAGINDLKTS  900
VS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A0.013921392Auxin response factor 5
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.104940.0floral meristem| flower| silique
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306865570.0
Genevisible255782_at0.0
Expression AtlasAT1G19850-
AtGenExpressAT1G19850-
ATTED-IIAT1G19850-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: In early embryo and during organ development.
UniprotTISSUE SPECIFICITY: Expressed in the whole plant with a lower expression in leaves. Detected in embryo axis, provascular tissues, procambium and some differentiated vascular regions of mature organs. {ECO:0000269|PubMed:10476078}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a transcription factor (IAA24) mediating embryo axis formation and vascular development. Similar to AUXIN RESPONSIVE FACTOR 1 (ARF1) shown to bind to auxin responsive elements (AREs), and to the maize transcriptional activator VIVIPAROUS 1( VP1). In situ hybridization shows expression in provascular tissue of embryos, the emerging shoot primordia, then is restricted to provascular tissue, and in the root central vascular cylinder.
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:14973283, ECO:0000269|PubMed:17553903}.
Function -- GeneRIF ? help Back to Top
  1. expression can be activated by auxin exposure
    [PMID: 17217464]
  2. auxin-derived positional information through MP carves out meristematic niches by locally overcoming a general differentiation-promoting activity involving AMP1.
    [PMID: 17553903]
  3. MONOPTEROS promotes the focusing of auxin and leaf initiation in part through pathways not affected by auxin efflux inhibitors.
    [PMID: 18685044]
  4. MP binds in vivo to two AuxRE-spanning fragments in the DRN promoter; MP is required for expression of DRN in cotyledon tips. Hence, DRN represents a direct target of MP and functions downstream of MP in cotyledon development
    [PMID: 19369397]
  5. TARGET OF MP 5 (TMO5) and TMO7 encode basic helix-loop-helix (bHLH) transcription factors that are expressed in the hypophysis-adjacent embryo cells, and are required and partially sufficient for MONOPTEROS-dependent root initiation
    [PMID: 20220754]
  6. Here we discuss putative mechanisms by which wide domains of MP expression could activate ATHB8 transcription in single cell files.
    [PMID: 20592815]
  7. MP with the domains III and IV eliminated can selectively uncouple a single ARF from regulation by Aux/IAA proteins.
    [PMID: 22320407]
  8. A semi-dominant, gain-of-function allele of MONOPTEROS is identified, which results in vein proliferation of leaves and cotyledons.
    [PMID: 22349732]
  9. MP mutant plant exhibits an adaxial-abaxial asymmetry in its ability to influence organ development.
    [PMID: 22751359]
  10. Characterization of Columbia alleles of mp, shows four new alleles among which one is a low-expression allele of mp and the another the strongest Columbia allele of mp.
    [PMID: 24281793]
  11. Study shows that ARF DNA-binding domains ahomodimerize to generate cooperative DNA binding, which is critical for in vivo ARF5/MP function. Strikingly, DNA-contacting residues are conserved between ARFs, and found that monomers have the same intrinsic specificity; ARF1 and ARF5 homodimers, however, differ in spacing tolerated between binding sites.
    [PMID: 24485461]
  12. A report or the crystal structure of ARF5 domain III/IV and the molecular determinants of ARF-IAA interactions.
    [PMID: 24710426]
  13. MONOPTEROS directly binds to the STOMAGEN promoter to suppress its expression in mesophyll and inhibit stomatal development.
    [PMID: 25002510]
  14. The involvement of ARF5 in the transcriptional regulation of the entire Aux/IAA family in Arabidopsis thaliana was studied.
    [PMID: 25145395]
  15. It was concluded that the MPDelta genotype can promote de novo shoot formation and can be used to probe corresponding signaling pathways.
    [PMID: 25274430]
  16. In this study, it is shown that MONOPTEROS (MP) directly activates the Dof5.8 promoter. Phenotypic analysis with the mp dof5.8 double mutants revealed that mutations within Dof5.8 enhanced the phenotype of a weak allele of mp.
    [PMID: 25336688]
  17. IAA17 and ARF5 associate to form homo- or hetero-oligomers using a common scaffold and binding interfaces, but their affinities vary significantly
    [PMID: 25512488]
  18. Analyses of the expression pattern of ARF7 and ARF5 targets suggest that this patterning mechanism controls flanking and central zone specification in Arabidopsis LR primordia.
    [PMID: 25944102]
  19. activating a steroid-inducible variant of the auxin response factor (ARF) MONOPTEROS (MP) is sufficient to restore patterning and PIN gene expression.
    [PMID: 27441727]
  20. TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls.
    [PMID: 27627746]
  21. These findings reveal a patterning module in plants that determines organ position by orienting transport of the hormone auxin toward cells with high levels of MP-mediated auxin signaling.
    [PMID: 27818174]
  22. MP plays a critical role in Arabidopsis embryonic root initiation.
    [PMID: 28265057]
  23. Adaxial-expressed MONOPTEROS (MP) and abaxial-enriched auxin together act as positional cues for patterning the WOX domain. MP directly binds to the WOX1 and PRS promoters and activates their expression.
    [PMID: 28943086]
  24. Auxin signaling in stem cells is mediated, at least in part, by AUXIN RESPONSE FACTOR 5/MONOPTEROS (ARF5/MP), which directly represses the transcription of DORNROSCHEN/ENHANCER OF SHOOT REGENERATION 1 (DRN/ESR1). DRN expressed in stem cells positively regulates CLAVATA3 (CLV3) expression and has important meristematic functions.
    [PMID: 29730265]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00153DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G19850.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT1G19850 (A)
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G01480(A), AT1G04550(A), AT1G12980(A), AT1G19850(A), AT1G73590(A), AT3G20840(A), AT4G11280(A), AT4G32880(A), AT4G37770(A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDauxin
Interaction ? help Back to Top
Source Intact With
BioGRIDAT1G19850, AT1G34310
IntActSearch P93024
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G19850
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF3347160.0AF334716.1 Arabidopsis thaliana clone C00027 (h) auxin response factor 5 (At1g19850) mRNA, complete cds.
GenBankBT0020500.0BT002050.1 Arabidopsis thaliana transcription factor (At1g19850) mRNA, complete cds.
GenBankBT0088050.0BT008805.1 Arabidopsis thaliana At1g19850 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_173414.10.0Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein
SwissprotP930240.0ARFE_ARATH; Auxin response factor 5
TrEMBLA0A178W9930.0A0A178W993_ARATH; Auxin response factor
STRINGAT1G19850.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58082746
Representative plantOGRP82601216
Publications ? help Back to Top
  1. Hamann T,Mayer U,J
    The auxin-insensitive bodenlos mutation affects primary root formation and apical-basal patterning in the Arabidopsis embryo.
    Development, 1999. 126(7): p. 1387-95
    [PMID:10068632]
  2. Ulmasov T,Hagen G,Guilfoyle TJ
    Activation and repression of transcription by auxin-response factors.
    Proc. Natl. Acad. Sci. U.S.A., 1999. 96(10): p. 5844-9
    [PMID:10318972]
  3. Ulmasov T,Hagen G,Guilfoyle TJ
    Dimerization and DNA binding of auxin response factors.
    Plant J., 1999. 19(3): p. 309-19
    [PMID:10476078]
  4. Deyholos MK,Cordner G,Beebe D,Sieburth LE
    The SCARFACE gene is required for cotyledon and leaf vein patterning.
    Development, 2000. 127(15): p. 3205-13
    [PMID:10887077]
  5. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  6. Ouellet F,Overvoorde PJ,Theologis A
    IAA17/AXR3: biochemical insight into an auxin mutant phenotype.
    Plant Cell, 2001. 13(4): p. 829-41
    [PMID:11283339]
  7. Hagen G,Guilfoyle T
    Auxin-responsive gene expression: genes, promoters and regulatory factors.
    Plant Mol. Biol., 2002 Jun-Jul. 49(3-4): p. 373-85
    [PMID:12036261]
  8. Long JA,Woody S,Poethig S,Meyerowitz EM,Barton MK
    Transformation of shoots into roots in Arabidopsis embryos mutant at the TOPLESS locus.
    Development, 2002. 129(12): p. 2797-806
    [PMID:12050130]
  9. Hamann T,Benkova E,Bäurle I,Kientz M,Jürgens G
    The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning.
    Genes Dev., 2002. 16(13): p. 1610-5
    [PMID:12101120]
  10. Aida M,Vernoux T,Furutani M,Traas J,Tasaka M
    Roles of PIN-FORMED1 and MONOPTEROS in pattern formation of the apical region of the Arabidopsis embryo.
    Development, 2002. 129(17): p. 3965-74
    [PMID:12163400]
  11. Mattsson J,Ckurshumova W,Berleth T
    Auxin signaling in Arabidopsis leaf vascular development.
    Plant Physiol., 2003. 131(3): p. 1327-39
    [PMID:12644682]
  12. Dharmasiri S,Dharmasiri N,Hellmann H,Estelle M
    The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis.
    EMBO J., 2003. 22(8): p. 1762-70
    [PMID:12682009]
  13. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  14. Tatematsu K, et al.
    MASSUGU2 encodes Aux/IAA19, an auxin-regulated protein that functions together with the transcriptional activator NPH4/ARF7 to regulate differential growth responses of hypocotyl and formation of lateral roots in Arabidopsis thaliana.
    Plant Cell, 2004. 16(2): p. 379-93
    [PMID:14729917]
  15. Hardtke CS, et al.
    Overlapping and non-redundant functions of the Arabidopsis auxin response factors MONOPTEROS and NONPHOTOTROPIC HYPOCOTYL 4.
    Development, 2004. 131(5): p. 1089-100
    [PMID:14973283]
  16. Nishimura T,Wada T,Okada K
    A key factor of translation reinitiation, ribosomal protein L24, is involved in gynoecium development in Arabidopsis.
    Biochem. Soc. Trans., 2004. 32(Pt 4): p. 611-3
    [PMID:15270688]
  17. Okushima Y, et al.
    Functional genomic analysis of the AUXIN RESPONSE FACTOR gene family members in Arabidopsis thaliana: unique and overlapping functions of ARF7 and ARF19.
    Plant Cell, 2005. 17(2): p. 444-63
    [PMID:15659631]
  18. Koizumi K, et al.
    VAN3 ARF-GAP-mediated vesicle transport is involved in leaf vascular network formation.
    Development, 2005. 132(7): p. 1699-711
    [PMID:15743878]
  19. Weijers D, et al.
    Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators.
    EMBO J., 2005. 24(10): p. 1874-85
    [PMID:15889151]
  20. Okushima Y,Mitina I,Quach HL,Theologis A
    AUXIN RESPONSE FACTOR 2 (ARF2): a pleiotropic developmental regulator.
    Plant J., 2005. 43(1): p. 29-46
    [PMID:15960614]
  21. Dharmasiri N, et al.
    Plant development is regulated by a family of auxin receptor F box proteins.
    Dev. Cell, 2005. 9(1): p. 109-19
    [PMID:15992545]
  22. Wang JW, et al.
    Control of root cap formation by MicroRNA-targeted auxin response factors in Arabidopsis.
    Plant Cell, 2005. 17(8): p. 2204-16
    [PMID:16006581]
  23. Nishimura T,Wada T,Yamamoto KT,Okada K
    The Arabidopsis STV1 protein, responsible for translation reinitiation, is required for auxin-mediated gynoecium patterning.
    Plant Cell, 2005. 17(11): p. 2940-53
    [PMID:16227452]
  24. Fukaki H,Nakao Y,Okushima Y,Theologis A,Tasaka M
    Tissue-specific expression of stabilized SOLITARY-ROOT/IAA14 alters lateral root development in Arabidopsis.
    Plant J., 2005. 44(3): p. 382-95
    [PMID:16236149]
  25. Weijers D, et al.
    Auxin triggers transient local signaling for cell specification in Arabidopsis embryogenesis.
    Dev. Cell, 2006. 10(2): p. 265-70
    [PMID:16459305]
  26. Dreher KA,Brown J,Saw RE,Callis J
    The Arabidopsis Aux/IAA protein family has diversified in degradation and auxin responsiveness.
    Plant Cell, 2006. 18(3): p. 699-714
    [PMID:16489122]
  27. Muto H, et al.
    Fluorescence cross-correlation analyses of the molecular interaction between an Aux/IAA protein, MSG2/IAA19, and protein-protein interaction domains of auxin response factors of arabidopsis expressed in HeLa cells.
    Plant Cell Physiol., 2006. 47(8): p. 1095-101
    [PMID:16854942]
  28. Wenzel CL,Schuetz M,Yu Q,Mattsson J
    Dynamics of MONOPTEROS and PIN-FORMED1 expression during leaf vein pattern formation in Arabidopsis thaliana.
    Plant J., 2007. 49(3): p. 387-98
    [PMID:17217464]
  29. Mitra SK,Gantt JA,Ruby JF,Clouse SD,Goshe MB
    Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.
    J. Proteome Res., 2007. 6(5): p. 1933-50
    [PMID:17432890]
  30. Ehrenreich IM,Stafford PA,Purugganan MD
    The genetic architecture of shoot branching in Arabidopsis thaliana: a comparative assessment of candidate gene associations vs. quantitative trait locus mapping.
    Genetics, 2007. 176(2): p. 1223-36
    [PMID:17435248]
  31. Vidaurre DP,Ploense S,Krogan NT,Berleth T
    AMP1 and MP antagonistically regulate embryo and meristem development in Arabidopsis.
    Development, 2007. 134(14): p. 2561-7
    [PMID:17553903]
  32. Cheng Y,Qin G,Dai X,Zhao Y
    NPY1, a BTB-NPH3-like protein, plays a critical role in auxin-regulated organogenesis in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(47): p. 18825-9
    [PMID:18000043]
  33. Szemenyei H,Hannon M,Long JA
    TOPLESS mediates auxin-dependent transcriptional repression during Arabidopsis embryogenesis.
    Science, 2008. 319(5868): p. 1384-6
    [PMID:18258861]
  34. Schuetz M,Berleth T,Mattsson J
    Multiple MONOPTEROS-dependent pathways are involved in leaf initiation.
    Plant Physiol., 2008. 148(2): p. 870-80
    [PMID:18685044]
  35. Swaminathan K,Peterson K,Jack T
    The plant B3 superfamily.
    Trends Plant Sci., 2008. 13(12): p. 647-55
    [PMID:18986826]
  36. Whitford R,Fernandez A,De Groodt R,Ortega E,Hilson P
    Plant CLE peptides from two distinct functional classes synergistically induce division of vascular cells.
    Proc. Natl. Acad. Sci. U.S.A., 2008. 105(47): p. 18625-30
    [PMID:19011104]
  37. Ploense SE,Wu MF,Nagpal P,Reed JW
    A gain-of-function mutation in IAA18 alters Arabidopsis embryonic apical patterning.
    Development, 2009. 136(9): p. 1509-17
    [PMID:19363152]
  38. Cole M, et al.
    DORNROSCHEN is a direct target of the auxin response factor MONOPTEROS in the Arabidopsis embryo.
    Development, 2009. 136(10): p. 1643-51
    [PMID:19369397]
  39. Thomas CL,Schmidt D,Bayer EM,Dreos R,Maule AJ
    Arabidopsis plant homeodomain finger proteins operate downstream of auxin accumulation in specifying the vasculature and primary root meristem.
    Plant J., 2009. 59(3): p. 426-36
    [PMID:19392692]
  40. Scacchi E, et al.
    Dynamic, auxin-responsive plasma membrane-to-nucleus movement of Arabidopsis BRX.
    Development, 2009. 136(12): p. 2059-67
    [PMID:19465596]
  41. Sato A,Yamamoto KT
    What's the physiological role of domain II-less Aux/IAA proteins?
    Plant Signal Behav, 2008. 3(7): p. 496-7
    [PMID:19704497]
  42. Donner TJ,Sherr I,Scarpella E
    Regulation of preprocambial cell state acquisition by auxin signaling in Arabidopsis leaves.
    Development, 2009. 136(19): p. 3235-46
    [PMID:19710171]
  43. De Smet I, et al.
    Bimodular auxin response controls organogenesis in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2010. 107(6): p. 2705-10
    [PMID:20133796]
  44. Schlereth A, et al.
    MONOPTEROS controls embryonic root initiation by regulating a mobile transcription factor.
    Nature, 2010. 464(7290): p. 913-6
    [PMID:20220754]
  45. Zhao Z, et al.
    Hormonal control of the shoot stem-cell niche.
    Nature, 2010. 465(7301): p. 1089-92
    [PMID:20577215]
  46. Donner TJ,Sherr I,Scarpella E
    Auxin signal transduction in Arabidopsis vein formation.
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