PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Migut.M01096.1.p

Common Name

MIMGU_mgv1a002959mg

Organism

Mimulus guttatus

Taxonomic ID

4155

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

ARF

Protein Properties

Length: 639aa MW: 70552.2 Da PI: 7.186

Description

ARF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.M01096.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	B3	78.2	8.4e-25	151	252	1	99
EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SS CS B3 1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgr 87 f+k+lt sd++++g +++p++ ae++ + +++ s++l+ +d++g +W++++iyr++++r++lt+GW+ Fv+ ++L +gD v+F + Migut.M01096.1.p 151 FCKTLTASDTSTHGGFSVPRRAAEDCfppldyK-QQRPSQELVAKDLHGVEWKFRHIYRGQPRRHLLTTGWSAFVNKKKLVSGDAVLFLR--G 240 99**************************963.3445679********************************************3..3 PP SEE..EEEEE-S CS B3 88 sefelvvkvfrk 99 ++el+++++r+ Migut.M01096.1.p 241 GDGELRLGIRRA 252 78999*9986 PP
2	Auxin_resp	112.9	3.1e-37	277	358	1	82
Auxin_resp 1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsL 82 +++++s++s+F+++YnPra +se +v+++k++k+l++++s GmRfk++fetedsserr+sG+++gv+++dp rWp+SkW++L Migut.M01096.1.p 277 VVNSISMRSTFNICYNPRAHSSEIIVPYHKFSKSLTHSFSCGMRFKIRFETEDSSERRCSGLIIGVNEVDPARWPGSKWKCL 358 67999****************************************************************************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101936	1.7E-42	147	258	IPR015300	DNA-binding pseudobarrel domain
Gene3D	G3DSA:2.40.330.10	1.1E-40	147	257	IPR015300	DNA-binding pseudobarrel domain
CDD	cd10017	8.32E-23	149	251	No hit	No description
PROSITE profile	PS50863	13.493	151	253	IPR003340	B3 DNA binding domain
SMART	SM01019	2.0E-24	151	253	IPR003340	B3 DNA binding domain
Pfam	PF02362	8.2E-23	151	252	IPR003340	B3 DNA binding domain
Pfam	PF06507	6.1E-32	278	358	IPR010525	Auxin response factor

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009734	Biological Process	auxin-activated signaling pathway
GO:0010050	Biological Process	vegetative phase change
GO:0010158	Biological Process	abaxial cell fate specification
GO:0010582	Biological Process	floral meristem determinacy
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 639 aa Download sequence Send to blast
MMCGLIDLNT VDNEDETASP SGSPTSSAAS GNFEFSVPPS SAAVCMELWH ACAGPLISLP 60 KKGSAVVYFP QGHLEQLREH TAVAYDLPPH VFCRVVDVKL HADAASDEVY AQVSLVPDQQ 120 IEQNWREGMI ETEVEDEDPE GMGKSMTPHM FCKTLTASDT STHGGFSVPR RAAEDCFPPL 180 DYKQQRPSQE LVAKDLHGVE WKFRHIYRGQ PRRHLLTTGW SAFVNKKKLV SGDAVLFLRG 240 GDGELRLGIR RAAQVKSNAT ILHPNSNHFN ASSVVAVVNS ISMRSTFNIC YNPRAHSSEI 300 IVPYHKFSKS LTHSFSCGMR FKIRFETEDS SERRCSGLII GVNEVDPARW PGSKWKCLLV 360 RWDDMDVNRL NRVSPWEIEL SGSVSGSNSF VLPGNKRGRV GFPHSAKPDL PVSRDGNEVS 420 DFGEPLRFQK VLQGQEVFAF RTPYAGAEAS RHHQSDMRCY PGLSMRHLHP DSFDTSVLGE 480 SFQFQNKVLQ GQETISLYGR GPQANHHTPQ VDNNAANIIN GVQVSNHGNS WSTLPQVFNS 540 NPHRSLPFQF TPSANHGDHG MVPTGGKEVA FPHRPVPTQQ FFRDNENFVS MCKNSCRLFG 600 FPLTEGKITT MGMGENATAS SGSASAYGVR DRLLDIAL*

Sequence ? help Back to Top

Protein Sequence Length: 639 aa Download sequence Send to blast

MMCGLIDLNT VDNEDETASP SGSPTSSAAS GNFEFSVPPS SAAVCMELWH ACAGPLISLP  60
KKGSAVVYFP QGHLEQLREH TAVAYDLPPH VFCRVVDVKL HADAASDEVY AQVSLVPDQQ  120
IEQNWREGMI ETEVEDEDPE GMGKSMTPHM FCKTLTASDT STHGGFSVPR RAAEDCFPPL  180
DYKQQRPSQE LVAKDLHGVE WKFRHIYRGQ PRRHLLTTGW SAFVNKKKLV SGDAVLFLRG  240
GDGELRLGIR RAAQVKSNAT ILHPNSNHFN ASSVVAVVNS ISMRSTFNIC YNPRAHSSEI  300
IVPYHKFSKS LTHSFSCGMR FKIRFETEDS SERRCSGLII GVNEVDPARW PGSKWKCLLV  360
RWDDMDVNRL NRVSPWEIEL SGSVSGSNSF VLPGNKRGRV GFPHSAKPDL PVSRDGNEVS  420
DFGEPLRFQK VLQGQEVFAF RTPYAGAEAS RHHQSDMRCY PGLSMRHLHP DSFDTSVLGE  480
SFQFQNKVLQ GQETISLYGR GPQANHHTPQ VDNNAANIIN GVQVSNHGNS WSTLPQVFNS  540
NPHRSLPFQF TPSANHGDHG MVPTGGKEVA FPHRPVPTQQ FFRDNENFVS MCKNSCRLFG  600
FPLTEGKITT MGMGENATAS SGSASAYGVR DRLLDIAL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ldv_A	1e-110	41	387	16	361	Auxin response factor 1
4ldw_A	1e-110	41	387	16	361	Auxin response factor 1
4ldw_B	1e-110	41	387	16	361	Auxin response factor 1
4ldx_A	1e-110	41	387	16	361	Auxin response factor 1
4ldx_B	1e-110	41	387	16	361	Auxin response factor 1
4ldy_A	1e-110	41	387	16	361	Auxin response factor 1
4ldy_B	1e-110	41	387	16	361	Auxin response factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Involved in the establishment or elaboration of tissue patterning during gynoecial development. {ECO:0000269\|PubMed:10952886, ECO:0000269\|PubMed:12036261}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00021	PBM	Transfer from AT2G33860	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.M01096.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by AHL21/GIK. {ECO:0000269\|PubMed:19956801}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012849069.1	0.0	PREDICTED: auxin response factor 3 isoform X1
Swissprot	O23661	0.0	ARFC_ARATH; Auxin response factor 3
TrEMBL	A0A022QL99	0.0	A0A022QL99_ERYGU; Auxin response factor

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA6101	23	33

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G33860.1	0.0	ARF family protein

Link Out ? help Back to Top
Phytozome	Migut.M01096.1.p

Publications ? help Back to Top
Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors. Mol. Gen. Mikrobiol. Virusol., 2013. [PMID:24003511] Thoma R,Chandler JW Polarity in the early floral meristem of Arabidopsis. Plant Signal Behav, 2015. 10(4): p. e992733 [PMID:25806573] Lora J,Hormaza JI,Herrero M Transition from two to one integument in Prunus species: expression pattern of INNER NO OUTER (INO), ABERRANT TESTA SHAPE (ATS) and ETTIN (ETT). New Phytol., 2015. 208(2): p. 584-95 [PMID:25991552] Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis. Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71 [PMID:26108442] Cabrera J, et al. Differentially expressed small RNAs in Arabidopsis galls formed by Meloidogyne javanica: a functional role for miR390 and its TAS3-derived tasiRNAs. New Phytol., 2016. 209(4): p. 1625-40 [PMID:26542733] Husbands AY,Benkovics AH,Nogueira FT,Lodha M,Timmermans MC The ASYMMETRIC LEAVES Complex Employs Multiple Modes of Regulation to Affect Adaxial-Abaxial Patterning and Leaf Complexity. Plant Cell, 2015. 27(12): p. 3321-35 [PMID:26589551] Yamaguchi N,Wu MF,Winter CM,Wagner D LEAFY and Polar Auxin Transport Coordinately Regulate Arabidopsis Flower Development. Plants (Basel), 2014. 3(2): p. 251-65 [PMID:27135503] Matsumura Y, et al. A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis. Biol Open, 2016. 5(7): p. 942-54 [PMID:27334696] Simonini S, et al. A noncanonical auxin-sensing mechanism is required for organ morphogenesis in Arabidopsis. Genes Dev., 2016. 30(20): p. 2286-2296 [PMID:27898393] Pfannebecker KC,Lange M,Rupp O,Becker A An Evolutionary Framework for Carpel Developmental Control Genes. Mol. Biol. Evol., 2017. 34(2): p. 330-348 [PMID:28049761] Wójcikowska B,Gaj MD Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis. Plant Cell Rep., 2017. 36(6): p. 843-858 [PMID:28255787] Su Z, et al. The THO Complex Non-Cell-Autonomously Represses Female Germline Specification through the TAS3-ARF3 Module. Curr. Biol., 2017. 27(11): p. 1597-1609.e2 [PMID:28552357] Simonini S,Bencivenga S,Trick M,Østergaard L Auxin-Induced Modulation of ETTIN Activity Orchestrates Gene Expression in Arabidopsis. Plant Cell, 2017. 29(8): p. 1864-1882 [PMID:28804059] Guan C, et al. Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis. Curr. Biol., 2017. 27(19): p. 2940-2950.e4 [PMID:28943086] Simonini S, et al. Corrigendum: A noncanonical auxin-sensing mechanism is required for organ morphogenesis in Arabidopsis. Genes Dev., 2017. 31(17): p. 1821 [PMID:28982764] Zhang K, et al. AUXIN RESPONSE FACTOR3 Regulates Floral Meristem Determinacy by Repressing Cytokinin Biosynthesis and Signaling. Plant Cell, 2018. 30(2): p. 324-346 [PMID:29371438] Vial-Pradel S, et al. Arabidopsis Zinc-Finger-Like Protein ASYMMETRIC LEAVES2 (AS2) and Two Nucleolar Proteins Maintain Gene Body DNA Methylation in the Leaf Polarity Gene ETTIN (ARF3). Plant Cell Physiol., 2018. 59(7): p. 1385-1397 [PMID:29415182] Simonini S,Stephenson P,Østergaard L A molecular framework controlling style morphology in Brassicaceae. Development, 2018. [PMID:29440299] Andres-Robin A, et al. Evidence for the Regulation of Gynoecium Morphogenesis by ETTIN via Cell Wall Dynamics. Plant Physiol., 2018. 178(3): p. 1222-1232 [PMID:30237208] Hablak SG Features inheritance of root system Arabidopsis thaliana (L.) Heynh. the interaction of genes CTR1 AND ALF3, NPH4 and IAR2. Tsitol. Genet., 2019. [PMID:30484609]