PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Manes.17G051300.2.p

Organism

Manihot esculenta

Taxonomic ID

3983

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

WOX

Protein Properties

Length: 386aa MW: 42379.5 Da PI: 8.1158

Description

WOX family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.17G051300.2.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	55.8	7.7e-18	57	117	2	57
T--SS--HHHHHHHHHHHHH.SSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 2 rkRttftkeqleeLeelFek.nrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 ++R+++++eq+++Le+ F++ +p ++e++++ ++l ++ +++V++WFqNr+ + k+ Manes.17G051300.2.p 57 KPRWNPKPEQIRILEAIFNSgMVNPPRDEIRKIRAQLqeygQVGDANVFYWFQNRKSRSKH 117 89***************99***********************************995 PP
2	Wus_type_Homeobox	112.2	2.8e-36	56	118	2	64
Wus_type_Homeobox 2 artRWtPtpeQikiLeelyksGlrtPnkeeiqritaeLeeyGkiedkNVfyWFQNrkaRerqk 64 +++RW+P+peQi+iLe++++sG+++P+++ei++i+a+L+eyG+++d+NVfyWFQNrk+R+++k Manes.17G051300.2.p 56 PKPRWNPKPEQIRILEAIFNSGMVNPPRDEIRKIRAQLQEYGQVGDANVFYWFQNRKSRSKHK 118 689**********************************************************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	2.87E-12	52	122	IPR009057	Homeodomain-like
PROSITE profile	PS50071	10.641	53	118	IPR001356	Homeobox domain
SMART	SM00389	6.8E-9	55	122	IPR001356	Homeobox domain
CDD	cd00086	1.04E-8	56	118	No hit	No description
Gene3D	G3DSA:1.10.10.60	8.1E-7	56	124	IPR009057	Homeodomain-like
Pfam	PF00046	2.0E-15	57	117	IPR001356	Homeobox domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 386 aa Download sequence Send to blast
MASSNRHWPS MFKSKPCNSH HHQWQHDITP SSLLSSACHR TPCASVPGCE ERSSEPKPRW 60 NPKPEQIRIL EAIFNSGMVN PPRDEIRKIR AQLQEYGQVG DANVFYWFQN RKSRSKHKLR 120 HLQNSMQQTH QAPSVTTSIP TLTAPSSSPS SSSEKSSPKA SQGTLSLTTP TVVDIFNSPT 180 GSVNQTYFQA HNEFVPEPFF FQAHQTGAGG GARPLTQGFC FSDLPNLVQV QDNTVGPCTS 240 LLLSEIMSSE ASKKYLYHED KNLKIQPRLS YPVTAPISHC IGFAPLPLPT THPNNVTVPS 300 TISQIQGESA SVGSSGAVRS TVFINDVAFE VGVGPFNLRE AFGDDFVLIH SSGQPVLTNE 360 WGVTFHSLQR GASYYLVPIS MNEHI*

Sequence ? help Back to Top

Protein Sequence Length: 386 aa Download sequence Send to blast

MASSNRHWPS MFKSKPCNSH HHQWQHDITP SSLLSSACHR TPCASVPGCE ERSSEPKPRW  60
NPKPEQIRIL EAIFNSGMVN PPRDEIRKIR AQLQEYGQVG DANVFYWFQN RKSRSKHKLR  120
HLQNSMQQTH QAPSVTTSIP TLTAPSSSPS SSSEKSSPKA SQGTLSLTTP TVVDIFNSPT  180
GSVNQTYFQA HNEFVPEPFF FQAHQTGAGG GARPLTQGFC FSDLPNLVQV QDNTVGPCTS  240
LLLSEIMSSE ASKKYLYHED KNLKIQPRLS YPVTAPISHC IGFAPLPLPT THPNNVTVPS  300
TISQIQGESA SVGSSGAVRS TVFINDVAFE VGVGPFNLRE AFGDDFVLIH SSGQPVLTNE  360
WGVTFHSLQR GASYYLVPIS MNEHI*

Functional Description ? help Back to Top
Source	Description
UniProt	Homeodomain transcription factor required for meristem growth and early development (PubMed:15753038). Promotes cell proliferation and prevents premature differentiation in meristematic tissues during postembryonic development (PubMed:15753038). Essential for maintaining tissue growth during embryogenesis (PubMed:17706632). May act by repressing TSS to promote meristematic proliferation (PubMed:21185286). Involved in the transcriptional activation of a subset of cytokinin response factors (PubMed:20110319). May act as a negative regulator of cytokinin signaling in the dark (PubMed:21057190). {ECO:0000269\|PubMed:15753038, ECO:0000269\|PubMed:17706632, ECO:0000269\|PubMed:20110319, ECO:0000269\|PubMed:21057190, ECO:0000303\|PubMed:21185286}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.17G051300.2.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated in the zygote after fertilization by the transcription factor WRKY2. {ECO:0000269\|PubMed:21316593}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021599024.1	0.0	WUSCHEL-related homeobox 9-like isoform X2
Swissprot	Q6X7J4	1e-85	WOX9_ARATH; WUSCHEL-related homeobox 9
TrEMBL	A0A2C9U661	0.0	A0A2C9U661_MANES; Uncharacterized protein
STRING	cassava4.1_023871m	0.0	(Manihot esculenta)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G45980.1	5e-70	WUSCHEL related homeobox 8

Link Out ? help Back to Top
Phytozome	Manes.17G051300.2.p

Publications ? help Back to Top
Wang W, et al. Dwarf Tiller1, a Wuschel-related homeobox transcription factor, is required for tiller growth in rice. PLoS Genet., 2014. 10(3): p. e1004154 [PMID:24625559] Zhu T,Moschou PN,Alvarez JM,Sohlberg JJ,von Arnold S Wuschel-related homeobox 8/9 is important for proper embryo patterning in the gymnosperm Norway spruce. J. Exp. Bot., 2014. 65(22): p. 6543-52 [PMID:25205582] Raines T, et al. The cytokinin response factors modulate root and shoot growth and promote leaf senescence in Arabidopsis. Plant J., 2016. 85(1): p. 134-47 [PMID:26662515] Dolzblasz A, et al. Stem Cell Regulation by Arabidopsis WOX Genes. Mol Plant, 2016. 9(7): p. 1028-39 [PMID:27109605] Blein T,Pautot V,Laufs P Combinations of Mutations Sufficient to Alter Arabidopsis Leaf Dissection. Plants (Basel), 2013. 2(2): p. 230-47 [PMID:27137374]