PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.01G044700.2.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family NAC
Protein Properties Length: 540aa    MW: 60796 Da    PI: 5.1417
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.01G044700.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM165.42.1e-5191361128
                  NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgk 88 
                          lp GfrF+Ptdeelv++yL+ k++g++ ++ +vi+e+d++k+ePwdLp  + +k++++ew+fF++ d+ky++g+r nrat++gyWkatgk
  Manes.01G044700.2.p   9 LPLGFRFRPTDEELVNFYLRLKINGNDEDV-RVIRELDVCKWEPWDLPdlSIIKTKDQEWFFFCPLDRKYPNGHRLNRATSKGYWKATGK 97 
                          699************************999.99**************96448888999******************************** PP

                  NAM  89 dkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                          d++++s +++l+g+kktLvfy+grap+g++t+Wv+heyr+
  Manes.01G044700.2.p  98 DRKIKS-GNNLIGMKKTLVFYTGRAPRGTRTHWVIHEYRA 136
                          ******.999****************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019412.62E-604159IPR003441NAC domain
PROSITE profilePS5100555.7689159IPR003441NAC domain
PfamPF023658.9E-2610135IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0002230Biological Processpositive regulation of defense response to virus by host
GO:0002237Biological Processresponse to molecule of bacterial origin
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0016021Cellular Componentintegral component of membrane
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0003713Molecular Functiontranscription coactivator activity
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 540 aa     Download sequence    Send to blast
MAVLSLSSLP LGFRFRPTDE ELVNFYLRLK INGNDEDVRV IRELDVCKWE PWDLPDLSII  60
KTKDQEWFFF CPLDRKYPNG HRLNRATSKG YWKATGKDRK IKSGNNLIGM KKTLVFYTGR  120
APRGTRTHWV IHEYRATEDD LDGTKPGQSP FVICRLFKKQ DDSVEGLNSE EPEATLSSPT  180
AAQSSPEVAE SDLALPQASP VNASPSNILS FNKCLNPHQS VVQTVDATTL EEDTQLEEDL  240
NWFVQPPEPL DDKLFSPLHA QVQAEAGCSY YNVNDWNSCN SGVQSHHITN ETDAAYVTSF  300
LNDILQQPVE HSCEGAGSIK NVAFDEYPES YVGLDAKITR TLLEEELQSP VWLEEEIDKK  360
PPLHVETIPE DNRSVTFLQL PLHNETYGGR SFASSSGTDQ LTNFQQISNH MNQIGSSESV  420
GTGIRIRARN PQNLPNAGNS AMQGLASRRL RLQCKLQVQP LQFGEKLKEH KLEQRVPEEL  480
KNRDKDASVG IDSCSTKDEH EQWRFFLSEN KEVSEELMPN PGSNVRLRSH ASMLKKVVA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A7e-46416312169NO APICAL MERISTEM PROTEIN
1ut4_B7e-46416312169NO APICAL MERISTEM PROTEIN
1ut7_A7e-46416312169NO APICAL MERISTEM PROTEIN
1ut7_B7e-46416312169NO APICAL MERISTEM PROTEIN
3swm_A8e-46416315172NAC domain-containing protein 19
3swm_B8e-46416315172NAC domain-containing protein 19
3swm_C8e-46416315172NAC domain-containing protein 19
3swm_D8e-46416315172NAC domain-containing protein 19
3swp_A8e-46416315172NAC domain-containing protein 19
3swp_B8e-46416315172NAC domain-containing protein 19
3swp_C8e-46416315172NAC domain-containing protein 19
3swp_D8e-46416315172NAC domain-containing protein 19
4dul_A7e-46416312169NAC domain-containing protein 19
4dul_B7e-46416312169NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator essential for the anti-viral defense called virus basal resistance response pathway (PubMed:11041886, PubMed:15629774, PubMed:18785827, PubMed:24418554). Not involved in HRT-mediated hypersensitive response (HR) and resistance to TCV (PubMed:18785827). Binds DNA non specifically (PubMed:15629774). Activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). {ECO:0000250|UniProtKB:Q9SCK6, ECO:0000269|PubMed:11041886, ECO:0000269|PubMed:15629774, ECO:0000269|PubMed:18785827, ECO:0000269|PubMed:24418554}.; FUNCTION: (Microbial infection) Compromised function in defense response pathway when interacting with the invading viral capsid protein (CP) of turnip crinkle virus (TCV) due to abnormal subcellular localization. {ECO:0000269|PubMed:11041886, ECO:0000269|PubMed:15629774}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.01G044700.2.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by bacterial pathogens type III effector proteins (TTEs). {ECO:0000269|PubMed:16553893}.; INDUCTION: (Microbial infection) Accumulates 2 days post infection with turnip crinkle virus (TCV) (PubMed:24418554). {ECO:0000269|PubMed:24418554}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKR6051410.0KR605141.1 Manihot esculenta NAC transcription factors 3 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021627360.10.0NAC domain-containing protein 91-like isoform X2
SwissprotQ9LKG81e-105NAC91_ARATH; NAC domain-containing protein 91
TrEMBLA0A2C9WK470.0A0A2C9WK47_MANES; Uncharacterized protein
STRINGcassava4.1_004348m0.0(Manihot esculenta)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G24590.21e-104TCV-interacting protein
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Hu W, et al.
    Genome-Wide Identification and Expression Analysis of the NAC Transcription Factor Family in Cassava.
    PLoS ONE, 2015. 10(8): p. e0136993
    [PMID:26317631]
  3. Ben Daniel BH, et al.
    Identification of novel transcriptional regulators of Zat12 using comprehensive yeast one-hybrid screens.
    Physiol Plant, 2016. 157(4): p. 422-41
    [PMID:26923089]
  4. Li Y, et al.
    The interaction between Turnip crinkle virus p38 and Cucumber mosaic virus 2b and its critical domains.
    Virus Res., 2016. 222: p. 94-105
    [PMID:27288723]