PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000935996
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family WRKY
Protein Properties Length: 573aa    MW: 62901.3 Da    PI: 7.2787
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000935996genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY106.31.6e-33230287260
                    --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS-- CS
           WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhek 60 
                    dDgynWrKYGqK+vkgse+prsYY+Ct+++Cp+kkkvers  d++++ei+Y+g+Hnh+k
  MDP0000935996 230 DDGYNWRKYGQKQVKGSENPRSYYKCTYPNCPTKKKVERSL-DGQITEIVYKGNHNHPK 287
                    8****************************************.***************85 PP
2WRKY103.99.1e-33401459159
                    ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
           WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                    ldDgy+WrKYGqK+vkg+++prsYY+Ct++gC+v+k+ver+++d ++v++tYeg+Hnh+
  MDP0000935996 401 LDDGYRWRKYGQKVVKGNPNPRSYYKCTYSGCSVRKHVERASHDLRAVITTYEGKHNHD 459
                    59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.4E-28221288IPR003657WRKY domain
SuperFamilySSF1182901.96E-25228288IPR003657WRKY domain
SMARTSM007749.2E-37229287IPR003657WRKY domain
PROSITE profilePS5081123.893230288IPR003657WRKY domain
PfamPF031061.2E-25230286IPR003657WRKY domain
Gene3DG3DSA:2.20.25.809.9E-37386461IPR003657WRKY domain
SuperFamilySSF1182906.67E-29393461IPR003657WRKY domain
PROSITE profilePS5081137.883396461IPR003657WRKY domain
SMARTSM007741.2E-37401460IPR003657WRKY domain
PfamPF031062.1E-25402459IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009753Biological Processresponse to jasmonic acid
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 573 aa     Download sequence    Send to blast
MASSSGSLET SANSHPAAFT FSTQPFMTTS FSDLLASGTD EDSNPPRYIG HGGLSDRIAE  60
RTGYGVPKFK SLPPPSLPIS PPSISPSSYF AIPPGLSPAE LLDSPVLLNT SNILPSPTTG  120
SFAAHGAFNW KNNQQNVKEE SKNYSDFSFQ TQARPPISSS SSMFQSSNTS IQTTQEQAWN  180
NYFQAQEPPK QEYGSVQSLS SEMTTKTLQN NTPANGGFYH QSQTLSRKSD DGYNWRKYGQ  240
KQVKGSENPR SYYKCTYPNC PTKKKVERSL DGQITEIVYK GNHNHPKPQN TRRSSSNSHA  300
IPASDPTNNE LPDQTYANHG NSQMDSIGTP ENSSISIGDD DFEQSSQRSK SGGGEEFDED  360
EPNAKKWKKE ADHNEGISAP GGRTVREPRV VVQTTSDIDI LDDGYRWRKY GQKVVKGNPN  420
PRSYYKCTYS GCSVRKHVER ASHDLRAVIT TYEGKHNHDV PAARGSGSHA AANRPIPNNN  480
NNNVASAMRT ITHHTNNSAN TNSLQNLRQP TSEGQAPFAV LEMLQSQGTY GFAGFDGNSM  540
GSYMNQTQXS DNMFSKAKEE PRDDAFFESL LR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-36230462878Probable WRKY transcription factor 4
2lex_A2e-36230462878Probable WRKY transcription factor 4
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.158570.0cell culture| fruit| leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: In dry seeds, expressed in aleurone cells and embryos. Levels drop rapidly but transiently in the embryos of imbibed seeds. {ECO:0000250|UniProtKB:Q6IEQ7}.
UniprotTISSUE SPECIFICITY: Expressed in aleurone cells. Mostly expressed in aleurone layers and leaves, and, to a lower extent, in roots, panicles and embryos. {ECO:0000250|UniProtKB:Q6IEQ7}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription repressor (By similarity). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (By similarity). {ECO:0000250|UniProtKB:Q6IEQ7, ECO:0000250|UniProtKB:Q6QHD1}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:25110688). Slightly down-regulated by gibberellic acid (GA) (By similarity). Accumulates in response to jasmonic acid (MeJA) (PubMed:16919842). {ECO:0000250|UniProtKB:Q6IEQ7, ECO:0000269|PubMed:16919842, ECO:0000269|PubMed:25110688}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008384716.20.0probable WRKY transcription factor 26
SwissprotQ6B6R41e-144WRK24_ORYSI; WRKY transcription factor WRKY24
TrEMBLA0A498IU590.0A0A498IU59_MALDO; Uncharacterized protein
STRINGXP_008384716.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF107734114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G38470.11e-111WRKY DNA-binding protein 33
Publications ? help Back to Top
  1. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]