PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000826293

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 497aa MW: 54002.2 Da PI: 10.1138

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000826293	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.2	1.4e-05	70	92	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H MDP0000826293 70 FVCEICNKGFQRDQNLQLHRRGH 92 89*******************88 PP
2	zf-C2H2	12.8	0.00037	146	168	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k + +s+ k H +t+ MDP0000826293 146 WKCEKCSKKYAVQSDWKAHSKTC 168 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	5.36E-7	69	92	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.6E-5	69	92	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.949	70	92	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	70	92	IPR015880	Zinc finger, C2H2-like
Pfam	PF12171	7.9E-5	70	92	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	72	92	IPR007087	Zinc finger, C2H2
SMART	SM00355	100	111	141	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.2E-4	134	167	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	5.36E-7	141	166	No hit	No description
SMART	SM00355	140	146	166	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 497 aa Download sequence Send to blast
MSGDGFSINM SSAIDGFAQD HQLNDNPSGG LKPNPPNAVA KKKRNLPGTP DPDAEVIGLS 60 PTTLMATNRF VCEICNKGFQ RDQNLQLHRR GHNLPWKLKQ RLNKEVKKKV YICPEKTCVH 120 HDPSRALGDL TGIKKHFSRK HGEKKWKCEK CSKKYAVQSD WKAHSKTCGT REYKCDCGTL 180 FSRKDSFITH RAFCDALTEE SARLTTSSVT GVHTNLNFGN DAMLNNPMMN NSQAVVQDAS 240 QISMQYGQGL MRQDFNGLDQ LHQHEKPRLS LWLNQQATSN SNQVNLIDDM QANPNHPLYV 300 TSSSSNAFPE MVQMPSSSNN VNLFGSSNSM PTFGASTNGA NLSLSPGQES GTSKLIGKNS 360 NLVGSGVSKP PAAPMSATAL LQKAAQLGST RSSNNQGSSL GVNVMSSSSS SRGFSNLNQN 420 RSNELHQVVQ NAHQSGGGSA NLSSLTSSSS NTSATTLEQL MNTIQRGPSN IGSIDHQNSL 480 TRDFFGHGRS RRRRTY*

Sequence ? help Back to Top

Protein Sequence Length: 497 aa Download sequence Send to blast

MSGDGFSINM SSAIDGFAQD HQLNDNPSGG LKPNPPNAVA KKKRNLPGTP DPDAEVIGLS  60
PTTLMATNRF VCEICNKGFQ RDQNLQLHRR GHNLPWKLKQ RLNKEVKKKV YICPEKTCVH  120
HDPSRALGDL TGIKKHFSRK HGEKKWKCEK CSKKYAVQSD WKAHSKTCGT REYKCDCGTL  180
FSRKDSFITH RAFCDALTEE SARLTTSSVT GVHTNLNFGN DAMLNNPMMN NSQAVVQDAS  240
QISMQYGQGL MRQDFNGLDQ LHQHEKPRLS LWLNQQATSN SNQVNLIDDM QANPNHPLYV  300
TSSSSNAFPE MVQMPSSSNN VNLFGSSNSM PTFGASTNGA NLSLSPGQES GTSKLIGKNS  360
NLVGSGVSKP PAAPMSATAL LQKAAQLGST RSSNNQGSSL GVNVMSSSSS SRGFSNLNQN  420
RSNELHQVVQ NAHQSGGGSA NLSSLTSSSS NTSATTLEQL MNTIQRGPSN IGSIDHQNSL  480
TRDFFGHGRS RRRRTY*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	3e-37	142	208	3	69	Zinc finger protein JACKDAW
5b3h_F	3e-37	142	208	3	69	Zinc finger protein JACKDAW
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.22782	0.0	bud\| fruit\| stem

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Strongly up-regulated during seed development. {ECO:0000269\|PubMed:21571950}.
Uniprot	TISSUE SPECIFICITY: At 3 days post anthesis (DPA), expressed in the chalazal endosperm region. By 6 DPA, expressed in the endosperm and embryo. In fully germinated seed, strongest expression in the root tip and not detected in the cotyledons. In 4-days old seedlings, restricted to the vasculature of the cotyledons, the shoot apical meristem region, and the root tip. By 8 days, restricted to newly emerged leaves. {ECO:0000269\|PubMed:21571950}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor promoting the transition to germination by regulating light and hormonal signaling during seed maturation (PubMed:21571950). Acts as a positive regulator of phytochrome and/or gibberellin action (PubMed:21571950, PubMed:25035403). {ECO:0000269\|PubMed:21571950, ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008369754.2	0.0	zinc finger protein JACKDAW-like
Swissprot	Q9LVQ7	1e-120	IDD1_ARATH; Zinc finger protein ENHYDROUS
TrEMBL	A0A498K1H4	0.0	A0A498K1H4_MALDO; Uncharacterized protein
STRING	XP_008369754.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G66730.1	1e-103	C2H2-like zinc finger protein

Link Out ? help Back to Top
Phytozome	MDP0000826293

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]