PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000787281
Common NameAP2D41
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ERF
Protein Properties Length: 277aa    MW: 29628.8 Da    PI: 8.9864
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000787281genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP262.11.2e-19142192255
            AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    +y+GVr+++ +g+++AeIrdp +ng  +r++lg+f tae+Aa a+++a+ +++g
  MDP0000787281 142 HYRGVRQRP-WGKFAAEIRDPAKNG--ARVWLGTFETAEDAALAYDRAAYRMRG 192
                    8********.***********9987..*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000182.58E-31141200No hitNo description
Gene3DG3DSA:3.30.730.102.5E-32141200IPR001471AP2/ERF domain
SuperFamilySSF541713.01E-23142202IPR016177DNA-binding domain
PROSITE profilePS5103224.21142200IPR001471AP2/ERF domain
SMARTSM003801.3E-39142206IPR001471AP2/ERF domain
PfamPF008471.1E-13142192IPR001471AP2/ERF domain
PRINTSPR003675.5E-11143154IPR001471AP2/ERF domain
PRINTSPR003675.5E-11166182IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001944Biological Processvasculature development
GO:0010200Biological Processresponse to chitin
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051301Biological Processcell division
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 277 aa     Download sequence    Send to blast
MYGQSGADSD YILLESIRRH FLGETDLLIG NPMSNSGSGP IFSRSSSFSS LYPCLTENWG  60
DLPLKEDDSE DMVLYGVLRD AVSVGWVPSG SADTCSYGFS VKSEPEVLPP VXRVPEKKAA  120
PVQPVQKSAE AVPAVVPAKG KHYRGVRQRP WGKFAAEIRD PAKNGARVWL GTFETAEDAA  180
LAYDRAAYRM RGSRALLNFP LRVNSGEPDP VRVTSKRSSS EPSSSSSENG SPKRRKKADG  240
SSPVQAGLEM GAGMGQKQVG GQXAVSVTRG EQLLVV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A4e-44138207170ATERF1
3gcc_A4e-44138207170ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.304440.0cell culture| fruit| leaf| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269|PubMed:11950980}.
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11950980, ECO:0000269|PubMed:9756931}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Also induced by methyl jasmonate (MeJA) independently of JAR1. Ethylene induction is completely dependent on a functional ETHYLENE-INSENSITIVE2 (EIN2), whereas induction by wounding does not need EIN2. Induction by salicylic acid (SA) seems to be independent of PAD4 and NPR1. Transcripts accumulate strongly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), cold, heat, NaCl or drought stress. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11950980}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGU7324650.0GU732465.1 Malus x domestica AP2 domain class transcription factor (AP2D41) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001315734.10.0ethylene-responsive transcription factor 1A-like
SwissprotO803374e-91EF100_ARATH; Ethylene-responsive transcription factor 1A
TrEMBLD5L1250.0D5L125_MALDO; AP2 domain class transcription factor
STRINGXP_008337947.10.0(Malus domestica)
STRINGXP_008352414.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF22393382
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G17500.12e-65ethylene responsive element binding factor 1
Publications ? help Back to Top
  1. Zimmermann P,Hirsch-Hoffmann M,Hennig L,Gruissem W
    GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox.
    Plant Physiol., 2004. 136(1): p. 2621-32
    [PMID:15375207]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Tacken E, et al.
    The role of ethylene and cold temperature in the regulation of the apple POLYGALACTURONASE1 gene and fruit softening.
    Plant Physiol., 2010. 153(1): p. 294-305
    [PMID:20237022]