PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000406270
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family bHLH
Protein Properties Length: 614aa    MW: 67831.8 Da    PI: 6.1337
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000406270genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.55.1e-13444490455
                    HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
            HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                    +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  MDP0000406270 444 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 490
                    799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142154.4E-5253241IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.047440489IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.10E-14443494No hitNo description
SuperFamilySSF474593.14E-18443504IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-10444490IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.106.7E-18444503IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.6E-16446495IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 614 aa     Download sequence    Send to blast
MKNEMGLGGG VWDDEDKAMV AAVLGTRAFD YLISSAVSSN ENSCMGIGTD ENLHNKLSDL  60
VERPNASNFS WNYAIFWQIS RSKSGDWVLC WGDGSCREPK EGEESETRRI LGLSLEDGTQ  120
QRMRKIVLQK LHNLFGSSDE YNGALGLDRV TDMEMFLLAS MYFSFPRGEE GPGKCFASGE  180
HVWLLDLLKS GSEYCVRSFL AKSAGIQTIV LVPTDVGVVE LGSVRCIGER LELLQSIRSL  240
FSXQSSHMRA KPVAGVPMIG RRRDENVQLT NLSPVERGEV VPKIFGQDLN SGNLVRPRYR  300
EKLAVRKLEE RPWDVYSNGN RIAFSSPPNG IHGSSWPHIH DVKQGSPTEM YASQSPVNNL  360
QELVNGVRDD FRHNQYQPQK QVPIQIDFSG ATSRPSVAPR PIGVDSENSD AEAPCKEDQP  420
GTADERRPRK RGRKPANGRE EPLNHVEAER QRREKLNQRF YALRAVVPNI SKMDKASLLG  480
DAIAYINELQ AXLKVMEAER ENLGGTSRDA SALGASSGME IQNQAPDVDI QAVNDEVIVR  540
VSCPLDSHPA SRVIEAFKEA QITVVESKLA SADDTVLHTF VVKSQGSERL TKEKLIAAFS  600
RESNSLHSLS SVG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A5e-29438503265Transcription factor MYC2
5gnj_B5e-29438503265Transcription factor MYC2
5gnj_E5e-29438503265Transcription factor MYC2
5gnj_F5e-29438503265Transcription factor MYC2
5gnj_G5e-29438503265Transcription factor MYC2
5gnj_I5e-29438503265Transcription factor MYC2
5gnj_M5e-29438503265Transcription factor MYC2
5gnj_N5e-29438503265Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1425433RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKR2598480.0KR259848.1 Prunus avium cultivar Tieton bHLH transcription factor (bHLH13) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028955372.10.0transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A498KJT30.0A0A498KJT3_MALDO; Uncharacterized protein
STRINGXP_008352118.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]