PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000390121
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ERF
Protein Properties Length: 329aa    MW: 36758.2 Da    PI: 8.8998
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000390121genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP262.68.4e-20138187255
            AP2   2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                    +y+GVr+++ +g+W+AeIrdp+    + +r++lg+f tae+Aa a+++a+++++g
  MDP0000390121 138 HYRGVRQRP-WGKWAAEIRDPK----KaARVWLGTFETAEDAAIAYDNAALRFKG 187
                    7********.**********94....45***********************9987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.101.3E-32137196IPR001471AP2/ERF domain
SMARTSM003803.4E-38138201IPR001471AP2/ERF domain
SuperFamilySSF541716.21E-22138196IPR016177DNA-binding domain
PROSITE profilePS5103224.619138195IPR001471AP2/ERF domain
CDDcd000182.07E-31138196No hitNo description
PfamPF008471.8E-12138187IPR001471AP2/ERF domain
PRINTSPR003671.9E-11139150IPR001471AP2/ERF domain
PRINTSPR003671.9E-11161177IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 329 aa     Download sequence    Send to blast
MRSLSSGHSK FKNRVPNRLV ARMTSTRLWY QSTSNWSSGL KVDRRHGKRP LPSEASEEKE  60
REDPPHHHHD FSSNYESSWT EADMSAMVSA LTQVIGTTEG HAAVQPNPTS ISDSSLLVKQ  120
EPDRSEPVQD QETVRRRHYR GVRQRPWGKW AAEIRDPKKA ARVWLGTFET AEDAAIAYDN  180
AALRFKGTKA KLNFPERVQG KTDFGILMGS SGTTTNSSSG AASTQRTQNL MRPAGQTAPA  240
PLITSQQPET FPDLYQYAQL LSSNDADFCN YSFYPFNQDP RFTSQFSPSS TNLSSSTASQ  300
DSQPSQPRRQ DHEEDAGNKD WNSSNPRE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A2e-27137198466ATERF1
3gcc_A2e-27137198466ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.146360.0cell culture| fruit| leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during the S phase of the cell cycle. {ECO:0000269|PubMed:23616605}.
UniprotTISSUE SPECIFICITY: Strongly expressed in proliferating cells. Detected in root tips, stipules, shoot apex, floral tissues, young siliques and abscission zones. {ECO:0000269|PubMed:23616605}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional regulator of cell proliferation and axillary bud outgrowth. Involved in maintaining the structure of the shoot apical meristem as well as plastochron and phyllotaxy. Activates several genes involved in cell cycle regulation and dormancy breaking, including CYCD3-3, DPA, and BARD1. Strongly down-regulates DRM1, DRMH1, MARD1 and several genes encoding different types of cell wall-remodeling proteins. {ECO:0000269|PubMed:23616605}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Transiently up-regulated 6 to 15 hours after decapitation. {ECO:0000269|PubMed:23616605}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGU7324500.0GU732450.1 Malus x domestica AP2 domain class transcription factor (AP2D26) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001306189.10.0ethylene-responsive transcription factor ERF113-like
SwissprotQ9FH543e-46EF114_ARATH; Ethylene-responsive transcription factor ERF114
TrEMBLA0A498IEH30.0A0A498IEH3_MALDO; Uncharacterized protein (Fragment)
STRINGXP_008390209.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF98534115
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G07310.11e-31ERF family protein
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Kong X, et al.
    PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis.
    Cell Rep, 2018. 22(5): p. 1350-1363
    [PMID:29386120]