PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000318013
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MYB
Protein Properties Length: 268aa    MW: 30375.2 Da    PI: 6.5166
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000318013genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding36.11.5e-11242848
                     HHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  8 EdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     Ed+ l ++++ +G g W+  +++ g++R++k+c++rw++yl
    MDP0000318013  2 EDKVLTEYIRIHGEGKWRNLPKRAGLKRCGKSCRLRWLNYL 42
                     9**************************************97 PP
2Myb_DNA-binding52.41.2e-164891146
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                     rg+ T +E+el+++++k+lG++ W++Ia +++ gRt++++k++w++
    MDP0000318013 48 RGNITHDEEELIIRLHKLLGNR-WSLIAGRLP-GRTDNEIKNYWNT 91
                     7999******************.*********.***********98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM007170.0018144IPR001005SANT/Myb domain
PROSITE profilePS5129412.556142IPR017930Myb domain
CDDcd001678.08E-7242No hitNo description
PfamPF002491.2E-9242IPR001005SANT/Myb domain
SuperFamilySSF466893.91E-24289IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.1E-19249IPR009057Homeodomain-like
PROSITE profilePS5129425.1014397IPR017930Myb domain
SMARTSM007175.6E-154795IPR001005SANT/Myb domain
PfamPF002491.5E-144891IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.606.7E-245096IPR009057Homeodomain-like
CDDcd001674.11E-115293No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 268 aa     Download sequence    Send to blast
MEDKVLTEYI RIHGEGKWRN LPKRAGLKRC GKSCRLRWLN YLRPDIKRGN ITHDEEELII  60
RLHKLLGNRW SLIAGRLPGR TDNEIKNYWN TTIGKRIQVE GRSCSDGNRR RPTQEKTKKP  120
TQSSPEPSTN NSCTKVVRTK ASRCTKMVLP HESHKFGDST EQVIDAAPIF EEVVNNPTVE  180
IDDPLSPMLF LDDENSTSEF LLDFKMDENF LSDFLNVDFS VLYNNEGAGK AAAAAATEDT  240
SNKLHGPDLQ SSMAPIVDSE LDCWLADN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A1e-2229714108B-MYB
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.148290.0fruit| leaf
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Highly expressed from the very early stages of embryogenesis to the globular stage, decreases rapidly from the late heart-torpedo stage and did not persist after the completion of embryogenesis.
UniprotTISSUE SPECIFICITY: Expressed at a high level in immature siliques and at a lower level in flowers. Undetected in young seedlings, roots, leaves and inflorescence stems.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator, when associated with BHLH2/EGL3/MYC146, BHLH12/MYC1, or BHLH42/TT8. Involved in the control of flavonoid late metabolism in developing siliques. Plays a key role in determining the tissue-specific activation of leucoanthocyanidin reductase (BANYULS). {ECO:0000269|PubMed:15361138}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankDQ0744630.0DQ074463.1 Malus x domestica MYB11 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001280958.11e-159uncharacterized protein LOC103453608
SwissprotQ9FJA26e-54TT2_ARATH; Transcription factor TT2
TrEMBLA0A498H7U30.0A0A498H7U3_MALDO; Uncharacterized protein
STRINGXP_008351076.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF3134817
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G35550.14e-56MYB family protein
Publications ? help Back to Top
  1. Coego A, et al.
    The TRANSPLANTA collection of Arabidopsis lines: a resource for functional analysis of transcription factors based on their conditional overexpression.
    Plant J., 2014. 77(6): p. 944-53
    [PMID:24456507]
  2. Liu C,Jun JH,Dixon RA
    MYB5 and MYB14 Play Pivotal Roles in Seed Coat Polymer Biosynthesis in Medicago truncatula.
    Plant Physiol., 2014. 165(4): p. 1424-1439
    [PMID:24948832]
  3. Zhu Z, et al.
    Characterization of the cis elements in the proximal promoter regions of the anthocyanin pathway genes reveals a common regulatory logic that governs pathway regulation.
    J. Exp. Bot., 2015. 66(13): p. 3775-89
    [PMID:25911741]
  4. Liu Y,Shi Z,Maximova SN,Payne MJ,Guiltinan MJ
    Tc-MYBPA an Arabidopsis TT2-like transcription factor and functions in the regulation of proanthocyanidin synthesis in Theobroma cacao.
    BMC Plant Biol., 2015. 15: p. 160
    [PMID:26109181]
  5. Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN
    The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors.
    Plant Physiol. Biochem., 2016. 102: p. 70-9
    [PMID:26913794]
  6. Li Y, et al.
    Two IIIf Clade-bHLHs from Freesia hybrida Play Divergent Roles in Flavonoid Biosynthesis and Trichome Formation when Ectopically Expressed in Arabidopsis.
    Sci Rep, 2016. 6: p. 30514
    [PMID:27465838]
  7. Li C,Zhang B,Chen B,Ji L,Yu H
    Site-specific phosphorylation of TRANSPARENT TESTA GLABRA1 mediates carbon partitioning in Arabidopsis seeds.
    Nat Commun, 2018. 9(1): p. 571
    [PMID:29422671]