PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000299277
Common NameAP2D27
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ERF
Protein Properties Length: 276aa    MW: 29642.6 Da    PI: 9.2523
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000299277genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP258.12.2e-18142192255
            AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    +y+GVr+++ +g+++AeIrdp +ng  +r++lg+f t e+Aa a+++a+ +++g
  MDP0000299277 142 HYRGVRQRP-WGKFAAEIRDPAKNG--ARVWLGTFETGEDAALAYDRAAYRMRG 192
                    8********.***********9987..*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000181.48E-29141200No hitNo description
Gene3DG3DSA:3.30.730.103.6E-31141200IPR001471AP2/ERF domain
PROSITE profilePS5103223.736142200IPR001471AP2/ERF domain
SuperFamilySSF541711.24E-22142202IPR016177DNA-binding domain
PfamPF008479.5E-14142192IPR001471AP2/ERF domain
SMARTSM003806.5E-38142206IPR001471AP2/ERF domain
PRINTSPR003672.0E-10143154IPR001471AP2/ERF domain
PRINTSPR003672.0E-10166182IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 276 aa     Download sequence    Send to blast
MYGQSGTDSD YALLDSIRRH LLGEMDFRIG NPMTNSGSGP LFSRSSSFSS LYPCLTQNWG  60
DLPLKEDDSE DMVLYGVLRD AVSVGWVPSG SADTLPYGFS VKSEPEVLPP VNMVQEKKAA  120
PVRPVQQSAQ XVPAAVPAKG KHYRGVRQRP WGKFAAEIRD PAKNGARVWL GTFETGEDAA  180
LAYDRAAYRM RGSXALLNFP LRVNSGEPDP VRLTSKRSSP EPSSSSSESG SPKRRKKANG  240
STPAQAGLEM GAGIGQQQVG VQVAVSVTXG EQLLVS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A1e-42138207170ATERF1
3gcc_A1e-42138207170ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.137840.0flower| fruit| leaf| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269|PubMed:11950980}.
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11950980, ECO:0000269|PubMed:9756931}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Also induced by methyl jasmonate (MeJA) independently of JAR1. Ethylene induction is completely dependent on a functional ETHYLENE-INSENSITIVE2 (EIN2), whereas induction by wounding does not need EIN2. Induction by salicylic acid (SA) seems to be independent of PAD4 and NPR1. Transcripts accumulate strongly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), cold, heat, NaCl or drought stress. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11950980}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGU7324510.0GU732451.1 Malus x domestica AP2 domain class transcription factor (AP2D27) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009333695.11e-162PREDICTED: ethylene-responsive transcription factor 2-like
SwissprotO803379e-84EF100_ARATH; Ethylene-responsive transcription factor 1A
TrEMBLA0A498JQ701e-157A0A498JQ70_MALDO; Uncharacterized protein
TrEMBLD5L1111e-157D5L111_MALDO; AP2 domain class transcription factor
STRINGXP_008352246.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF22393382
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G17500.14e-62ethylene responsive element binding factor 1
Publications ? help Back to Top
  1. Zimmermann P,Hirsch-Hoffmann M,Hennig L,Gruissem W
    GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox.
    Plant Physiol., 2004. 136(1): p. 2621-32
    [PMID:15375207]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Tacken E, et al.
    The role of ethylene and cold temperature in the regulation of the apple POLYGALACTURONASE1 gene and fruit softening.
    Plant Physiol., 2010. 153(1): p. 294-305
    [PMID:20237022]