PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000287358
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family bHLH
Protein Properties Length: 933aa    MW: 105772 Da    PI: 7.8351
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000287358genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH29.41.4e-0981142255
                    HHHHHHHHHHHHHHHHHHHHHHHCTSCC.C.........TTS-.STCHHHHHHHHHHHHHHH CS
            HLH   2 rrahnerErrRRdriNsafeeLrellPk.as......kapskK.lsKaeiLekAveYIksLq 55 
                    r+  + +E++RR++++  f++L +l+P+ +s      +++s    s  + L  Av+YIk+Lq
  MDP0000287358  81 RTDRKTIEKNRRNQMKALFSKLNSLVPHqRSrvslslSESSLWeASLPDQLDDAVNYIKKLQ 142
                    778899**********************666*****977777679****************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000837.69E-577146No hitNo description
PROSITE profilePS5088810.82379141IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.4E-1081155IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.83E-981155IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.9E-581142IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
HamapMF_0300366.258373898IPR007783Eukaryotic translation initiation factor 3 subunit D
PfamPF050918.6E-194379886IPR007783Eukaryotic translation initiation factor 3 subunit D
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005852Cellular Componenteukaryotic translation initiation factor 3 complex
GO:0003743Molecular Functiontranslation initiation factor activity
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 933 aa     Download sequence    Send to blast
MKRRSKKDLN TQGIKSNNKM IKRDYVSPPF VHEESNDTQV VWELERLCIS FVPFRFNIKW  60
ILFDIFLVWN ILMEKCPSSS RTDRKTIEKN RRNQMKALFS KLNSLVPHQR SRVSLSLSES  120
SLWEASLPDQ LDDAVNYIKK LQTNLEKLRE KKDRLMGIEK SSHCNAGFGR SGGAITEGLN  180
SSPLVEIHEM GSALGVLMIT GLDHQFMFNE SIRVIQEEGA DIVNASFSVV KDTIFHTIHS  240
KVRESAAAGS VAARISERLK KFVNDQDVWG ARIVVRDSYG VFVAAFVRKS ANVFSPRQAE  300
AMAVRAGRTP RTLVDIQDPE SPTIHNGQGQ NGKFTWHDNR THTRVLSANP TGSKASDFHC  360
LPLNLTNSAI MVEGFEVGGV PFNPDGWGPP DSATTPTTTS NLPQNVPFAP FSRSEKLGRI  420
ADWTRTFNNP ARSKNPSDAV FDFSNGESFP GSADDDASFR LVDGKPPPRP RFGPKWRFQQ  480
QRQLPHRRDE EVEAKKREAE KERARRDRQY NMNRSNVNAP RREAAVFKSS VDIQPEWNML  540
EQIPFSTFSK LSFSVPEPED LLFCGGLEFY DRSVDRITPK NERRLERFKN RNFFKVTTTD  600
DPVIRRLANE DKATVFATDT ILSTLMCAPR SVYSWXIVVQ KVGNKLFFDK RDGSQLDLLS  660
VHETSQEPLP EAKDDINSAY SLSVEAAYIN QNFSQQVLVR DGNKVTFDEP NPFANEGEEV  720
ASVAYRYRRW KLEEGMYLVA RCEVQSVMEV NNQRSFLTLN ALNEFDPKYS GVDWRQKLET  780
QRGAVLATEL KNNANKLAKW TAQALLASAD LMKLGYVSRV HPRDHFNHVI LAVVGYKPKE  840
FASQINLNQN SMWGIVKSIV DLCMKLSEGK YVLVKDPSKP QVRIYEVPPD AFENDYVEEP  900
LPEDEQVQPP TEEGQGAEPN VAANDVEDKP LDA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5k4b_A1e-1375298922368Eukaryotic translation initiation factor 3 subunit D
5k4b_B1e-1375298922368Eukaryotic translation initiation factor 3 subunit D
5k4c_A1e-1375298922368Eukaryotic translation initiation factor 3 subunit D
5k4d_A1e-1375298922368Eukaryotic translation initiation factor 3 subunit D
5k4d_B1e-1375298922368Eukaryotic translation initiation factor 3 subunit D
6fec_91e-1375298922368EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.89840.0bud| cell culture| fruit| leaf| root
Functional Description ? help Back to Top
Source Description
UniProtmRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. {ECO:0000255|HAMAP-Rule:MF_03003}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008383726.20.0eukaryotic translation initiation factor 3 subunit D-like
SwissprotP568200.0EIF3D_ARATH; Eukaryotic translation initiation factor 3 subunit D
TrEMBLA0A498IVN40.0A0A498IVN4_MALDO; Eukaryotic translation initiation factor 3 subunit D
STRINGXP_008383726.10.0(Malus domestica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20970.11e-37bHLH family protein
Publications ? help Back to Top
  1. Burks EA,Bezerra PP,Le H,Gallie DR,Browning KS
    Plant initiation factor 3 subunit composition resembles mammalian initiation factor 3 and has a novel subunit.
    J. Biol. Chem., 2001. 276(3): p. 2122-31
    [PMID:11042177]
  2. Kubis S, et al.
    The Arabidopsis ppi1 mutant is specifically defective in the expression, chloroplast import, and accumulation of photosynthetic proteins.
    Plant Cell, 2003. 15(8): p. 1859-71
    [PMID:12897258]