PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000250487

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

NAC

Protein Properties

Length: 282aa MW: 31735.3 Da PI: 5.194

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000250487	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	111.1	1.2e-34	79	198	5	128
NAM 5 frFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk....k 96 frF+Ptdeelvv++L++k++ +++ +vi+++++y ++Pw+L+ k+ +e k+wyf+s+++ +nr+t++gyWk+ g +++++s+ + MDP0000250487 79 FRFDPTDEELVVHFLQRKATLLPFHP-DVIPDLHLYPYDPWELNGKALSEGKQWYFYSRKA--------QNRVTSNGYWKTLGIEEPIFSSsssnS 165 9********************999.99**********97777889**9974........58***************977666 PP NAM 97 gelvglkktLvfykgrapk.gektdWvmheyrl 128 +++vg+k+ L+fy g+ap+ g kt+W+mheyrl MDP0000250487 166 TSKVGMKRYLTFYVGEAPNsGIKTNWIMHEYRL 198 667******997765289*******98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51005	40.248	75	249	IPR003441	NAC domain
SuperFamily	SSF101941	1.83E-40	77	208	IPR003441	NAC domain
Pfam	PF02365	7.3E-22	79	198	IPR003441	NAC domain
SuperFamily	SSF101941	1.83E-40	237	245	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 282 aa Download sequence Send to blast
MASPTVTFQN RRLGPSPIFW SEDARPRTRE THAPDVALGL AIDAGPTPRA SLVTRATQRW 60 TLSPQQFGPI TSLSSLLVFR FDPTDEELVV HFLQRKATLL PFHPDVIPDL HLYPYDPWEL 120 NGKALSEGKQ WYFYSRKAQN RVTSNGYWKT LGIEEPIFSS SSSNSTSKVG MKRYLTFYVG 180 EAPNSGIKTN WIMHEYRLSS SASDCASSST TTTTTTRSSK RRGQPKTVSN ACVATHEYSG 240 YILCRVYERD EEEDDDDDGT ELSCLDEVFL SLDDLDEISL PN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3swm_A	1e-32	62	222	7	169	NAC domain-containing protein 19
3swm_B	1e-32	62	222	7	169	NAC domain-containing protein 19
3swm_C	1e-32	62	222	7	169	NAC domain-containing protein 19
3swm_D	1e-32	62	222	7	169	NAC domain-containing protein 19
3swp_A	1e-32	62	222	7	169	NAC domain-containing protein 19
3swp_B	1e-32	62	222	7	169	NAC domain-containing protein 19
3swp_C	1e-32	62	222	7	169	NAC domain-containing protein 19
3swp_D	1e-32	62	222	7	169	NAC domain-containing protein 19
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.15312	0.0	fruit

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in root xylem vessels (PubMed:15923329). Expressed in stems, vascular tissue of cauline leaves and tracheary elements of sepals (PubMed:18069942). {ECO:0000269\|PubMed:15923329, ECO:0000269\|PubMed:18069942}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that influences tracheary elements and xylem development by negatively regulating secondary cell wall fiber synthesis and programmed cell death. {ECO:0000269\|PubMed:18069942, ECO:0000269\|PubMed:20458494}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028963145.1	1e-150	NAC domain-containing protein 104-like isoform X1
Swissprot	Q8GWK6	1e-74	NC104_ARATH; NAC domain-containing protein 104
TrEMBL	D9ZJ88	1e-106	D9ZJ88_MALDO; NAC domain class transcription factor
STRING	XP_009333606.1	1e-113	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1736	33	95

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G64530.1	2e-68	xylem NAC domain 1

Link Out ? help Back to Top
Phytozome	MDP0000250487

Publications ? help Back to Top
Zhao C, et al. XYLEM NAC DOMAIN1, an angiosperm NAC transcription factor, inhibits xylem differentiation through conserved motifs that interact with RETINOBLASTOMA-RELATED. New Phytol., 2017. 216(1): p. 76-89 [PMID:28742236] Tang N, et al. Natural variation at XND1 impacts root hydraulics and trade-off for stress responses in Arabidopsis. Nat Commun, 2018. 9(1): p. 3884 [PMID:30250259]