PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000198235
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family NAC
Protein Properties Length: 148aa    MW: 16592.1 Da    PI: 8.2043
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000198235genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM124.77.5e-39251422117
            NAM   2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk.. 95 
                    +pGfrFhPtdeel+++yL+ kv + ++     i+evd++++ePw+Lp  +k +e+ewyfFs rd+ky+tg r+nrat +gyWkatgkd++v+s+  
  MDP0000198235  25 QPGFRFHPTDEELITFYLASKVYNGSFCG-VRIAEVDLNRCEPWELPDVAKMGEREWYFFSLRDRKYPTGMRTNRATGAGYWKATGKDRQVFSAst 119
                    69************************777.45***************8888899**************************************9987 PP

            NAM  96 kgelvglkktLvfy.kgrapkge 117
                    +g l g+kk  ++  +grap+++
  MDP0000198235 120 GGXLLGMKKXXALVlQGRAPRAT 142
                    8889*****87776578999876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.31E-4221141IPR003441NAC domain
PROSITE profilePS5100540.57224148IPR003441NAC domain
PfamPF023651.5E-1726130IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 148 aa     Download sequence    Send to blast
MLGIGMEEIM SELMSGEDEN GQGFQPGFRF HPTDEELITF YLASKVYNGS FCGVRIAEVD  60
LNRCEPWELP DVAKMGEREW YFFSLRDRKY PTGMRTNRAT GAGYWKATGK DRQVFSASTG  120
GXLLGMKKXX ALVLQGRAPR ATRPSGHA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A5e-362614319132NO APICAL MERISTEM PROTEIN
1ut4_B5e-362614319132NO APICAL MERISTEM PROTEIN
1ut7_A5e-362614319132NO APICAL MERISTEM PROTEIN
1ut7_B5e-362614319132NO APICAL MERISTEM PROTEIN
3swm_A5e-362614322135NAC domain-containing protein 19
3swm_B5e-362614322135NAC domain-containing protein 19
3swm_C5e-362614322135NAC domain-containing protein 19
3swm_D5e-362614322135NAC domain-containing protein 19
3swp_A5e-362614322135NAC domain-containing protein 19
3swp_B5e-362614322135NAC domain-containing protein 19
3swp_C5e-362614322135NAC domain-containing protein 19
3swp_D5e-362614322135NAC domain-containing protein 19
4dul_A5e-362614319132NAC domain-containing protein 19
4dul_B5e-362614319132NAC domain-containing protein 19
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: First expressed at the globular stage, mostly in the apical part of the embryo. During the triangular stage, confined to the boundary of emerging cotyledons. Later restricted to the center of the apical part of the embryo and to seedling apex, at the boundaries of the cotyledon margins and the boundaries between the SAM and the cotyledons. Localized in a one-cell-wide ring at the boundary between trichomes or lateral roots and epidermis. Accumulates at the boundaries between leaf primordia and the shoot meristem and between floral primordia and the inflorescence meristem. Found in the adaxial axils of secondary inflorescences and pedicels, and in axiallary buds. In flowers, expressed in a ring at the bases of sepals and petals. In carpels, confined to the boundaries between ovule primordia. In ovules, localized in a ring at the boundary between the nucellus and the chalaza. In the mature embryo sac, detected in the two polar nuclei of the central cell. {ECO:0000269|PubMed:12837947, ECO:0000269|PubMed:17122068}.
UniprotTISSUE SPECIFICITY: In a general manner, present at the boundaries between mersitems and araising primordia. {ECO:0000269|PubMed:12837947}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for axillary meristem initiation and separation of the meristem from the main stem. May act as an inhibitor of cell division. {ECO:0000269|PubMed:12837947, ECO:0000269|PubMed:17122068}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By BRM, at the chromatin level, and conferring a very specific spatial expression pattern. {ECO:0000269|PubMed:16854978}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF1981210.0KF198121.1 Malus hupehensis NAC domain protein (NAC80) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008373384.24e-89protein CUP-SHAPED COTYLEDON 3
SwissprotQ9S8516e-65NAC31_ARATH; Protein CUP-SHAPED COTYLEDON 3
TrEMBLS5RSI91e-103S5RSI9_MALHU; NAC domain protein
STRINGXP_008346452.15e-90(Malus domestica)
STRINGXP_008373384.11e-88(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF78883347
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G76420.12e-67NAC family protein
Publications ? help Back to Top
  1. Chen C, et al.
    Transcriptome profiling reveals roles of meristem regulators and polarity genes during fruit trichome development in cucumber (Cucumis sativus L.).
    J. Exp. Bot., 2014. 65(17): p. 4943-58
    [PMID:24962999]
  2. Gonçalves B, et al.
    A conserved role for CUP-SHAPED COTYLEDON genes during ovule development.
    Plant J., 2015. 83(4): p. 732-42
    [PMID:26119568]
  3. Balkunde R,Kitagawa M,Xu XM,Wang J,Jackson D
    SHOOT MERISTEMLESS trafficking controls axillary meristem formation, meristem size and organ boundaries in Arabidopsis.
    Plant J., 2017. 90(3): p. 435-446
    [PMID:28161901]
  4. Espinosa-Ruiz A, et al.
    TOPLESS mediates brassinosteroid control of shoot boundaries and root meristem development in Arabidopsis thaliana.
    Development, 2017. 144(9): p. 1619-1628
    [PMID:28320734]
  5. Koyama T,Sato F,Ohme-Takagi M
    Roles of miR319 and TCP Transcription Factors in Leaf Development.
    Plant Physiol., 2017. 175(2): p. 874-885
    [PMID:28842549]