PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000189033
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ERF
Protein Properties Length: 269aa    MW: 29609.2 Da    PI: 5.6761
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000189033genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP264.71.9e-20126176255
            AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    +++GVr+++ +g+++AeIrdp++ng  +r++lg++ tae+Aa a+++a+ k++g
  MDP0000189033 126 HFRGVRRRP-WGKYAAEIRDPKKNG--ARVWLGTYETAEGAALAYDQAAFKMRG 176
                    69*******.***********9998..*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000181.11E-30125186No hitNo description
PfamPF008473.2E-14126176IPR001471AP2/ERF domain
PROSITE profilePS5103223.749126184IPR001471AP2/ERF domain
SuperFamilySSF541712.55E-22126185IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.104.3E-32126185IPR001471AP2/ERF domain
SMARTSM003808.0E-39126190IPR001471AP2/ERF domain
PRINTSPR003675.5E-13127138IPR001471AP2/ERF domain
PRINTSPR003675.5E-13166186IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 269 aa     Download sequence    Send to blast
MFEHIYLEAD FALLESILLD DNFDTNLQES SATASGSPPP MYCRSLSFSK LFLTKSWSDM  60
PFKVELEDTN DVVGALSDGT DGWSMSSDHH HVDVIETTPA KPEPQEVVRE EIVVARETCT  120
PLLGQHFRGV RRRPWGKYAA EIRDPKKNGA RVWLGTYETA EGAALAYDQA AFKMRGSKAK  180
LNFPHLIGSG CEPVRVTGKR RAPEVSSSSS SSDSGPPKLK RRNSGVGSGA EARSGSTSRV  240
EMVEMSQLAV VDQWLSDLNT TVYSMPINY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A5e-32124190369ATERF1
3gcc_A5e-32124190369ATERF1
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots and at low levels in buds and leaves. Not expressed in cell culture. {ECO:0000269|PubMed:7756828}.
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional activator and may be involved in disease resistance pathways. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase cascade, and to be influenced by methyl-jasmonate. {ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:10792818, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by ethephon (ethylene-releasing compound) in buds and to a lower extent in leaves. Strongly induced by cycloheximide and mechanical stimuli. Wounding leads to a both local and systemic expression, independently of ethylene, and through a de-novo-protein-synthesis-independent regulation. Wound induction is reduced by methyl-jasmonate. Induction by purified xylanase from Trichoderma viride (TvX) and another elicitor from Phytophthora infestans (PiE), that appears to be mediated by both protein kinases and protein phosphatases. {ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:12090623, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008344394.10.0ethylene-responsive transcription factor 2-like
SwissprotQ404797e-52ERF2_TOBAC; Ethylene-responsive transcription factor 2
TrEMBLA0A498KM990.0A0A498KM99_MALDO; Uncharacterized protein
STRINGXP_008344394.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF51233157
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G44840.11e-41ethylene-responsive element binding factor 13
Publications ? help Back to Top
  1. Nakano T,Nishiuchi T,Suzuki K,Fujimura T,Shinshi H
    Studies on transcriptional regulation of endogenous genes by ERF2 transcription factor in tobacco cells.
    Plant Cell Physiol., 2006. 47(4): p. 554-8
    [PMID:16452120]