PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000178398

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

ERF

Protein Properties

Length: 220aa MW: 24141 Da PI: 7.1293

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000178398	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	55.6	1.3e-17	95	144	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++GVr+++ +g+++AeIrdp++ng +r++lg++ ta +A a+++a+ k++g MDP0000178398 95 FRGVRQRP-WGKYAAEIRDPKKNG--ARIWLGTYETAVDAGLAYDRAAFKMRG 144 8*****.*******9998..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	6.20E-30	94	154	No hit	No description
PROSITE profile	PS51032	21.931	94	152	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.1E-30	94	153	IPR001471	AP2/ERF domain
SMART	SM00380	6.9E-36	94	158	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.7E-13	95	106	IPR001471	AP2/ERF domain
Pfam	PF00847	2.1E-11	95	144	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.42E-21	95	153	IPR016177	DNA-binding domain
PRINTS	PR00367	2.7E-13	134	154	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 220 aa Download sequence Send to blast
MSTESMSRSN WALLESIRQH LLHDDFETQE TFLADVAELD APSLNSPSTS SSSNAHFLVE 60 DLGDTMGIMN HXLDTSNNFE VAACVVQVPQ SGRNFRGVRQ RPWGKYAAEI RDPKKNGARI 120 WLGTYETAVD AGLAYDRAAF KMRGSKAKLN FPHLIGTHDS EPGRVASXRC SLKPSSSSVL 180 SSDGGGSPTL KRKRNVVCSA XKAKLEEGDE PFXVFQLNSF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	4e-31	92	152	3	63	ATERF1
3gcc_A	4e-31	92	152	3	63	ATERF1
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots and at low levels in buds and leaves. Not expressed in cell culture. {ECO:0000269\|PubMed:7756828}.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator and may be involved in disease resistance pathways. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase cascade, and to be influenced by methyl-jasmonate. {ECO:0000269\|PubMed:10652129, ECO:0000269\|PubMed:10792818, ECO:0000269\|PubMed:7756828, ECO:0000269\|Ref.2}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by ethephon (ethylene-releasing compound) in buds and to a lower extent in leaves. Strongly induced by cycloheximide and mechanical stimuli. Wounding leads to a both local and systemic expression, independently of ethylene, and through a de-novo-protein-synthesis-independent regulation. Wound induction is reduced by methyl-jasmonate. Induction by purified xylanase from Trichoderma viride (TvX) and another elicitor from Phytophthora infestans (PiE), that appears to be mediated by both protein kinases and protein phosphatases. {ECO:0000269\|PubMed:10652129, ECO:0000269\|PubMed:12090623, ECO:0000269\|PubMed:7756828, ECO:0000269\|Ref.2}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008370115.2	1e-161	ethylene-responsive transcription factor 2-like
Swissprot	Q40479	1e-44	ERF2_TOBAC; Ethylene-responsive transcription factor 2
TrEMBL	A0A498JJA7	1e-160	A0A498JJA7_MALDO; Uncharacterized protein
STRING	XP_008370115.1	1e-160	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF512	33	157

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G44840.1	1e-38	ethylene-responsive element binding factor 13

Link Out ? help Back to Top
Phytozome	MDP0000178398

Publications ? help Back to Top
Nakano T,Nishiuchi T,Suzuki K,Fujimura T,Shinshi H Studies on transcriptional regulation of endogenous genes by ERF2 transcription factor in tobacco cells. Plant Cell Physiol., 2006. 47(4): p. 554-8 [PMID:16452120]