PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000172065
Common NameAP2D35
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ERF
Protein Properties Length: 238aa    MW: 26603.7 Da    PI: 8.0867
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000172065genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP259.39.2e-19549149
            AP2  1 sgykGVrwdkkrgrWvAeIrdpsengkr..krfslgkfgtaeeAakaaiaa 49
                   ++y+GVr+++ +g+Wv+eIr+p        +r++lg+f taeeAa+a+++a
  MDP0000172065  5 KKYRGVRQRH-WGSWVSEIRHP-----LlkRRVWLGTFETAEEAARAYDEA 49
                   59*******9.**********8.....334********************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000181.97E-34564No hitNo description
PfamPF008476.6E-12649IPR001471AP2/ERF domain
SuperFamilySSF541712.75E-20664IPR016177DNA-binding domain
PROSITE profilePS5103221.97663IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.109.3E-33663IPR001471AP2/ERF domain
SMARTSM003808.4E-37669IPR001471AP2/ERF domain
PRINTSPR003674.7E-11718IPR001471AP2/ERF domain
PRINTSPR003674.7E-112945IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 238 aa     Download sequence    Send to blast
MVKSKKYRGV RQRHWGSWVS EIRHPLLKRR VWLGTFETAE EAARAYDEAS VLMSGRNAKT  60
NFPIXTXTTQ SNGTRTTVGS SDHPKTSSGD LDSRSEQKGL SEILHAKLRK CGKIPSPSMT  120
CLRLDNESSH IGVWQKRAGQ RSDNSNWVMT VPLGKKKNNS TVDTNNADDQ SVLSSQFMSN  180
SDQSASIETS SERXPQXMAE MDEEEKIALQ MIEELLNGNC ASSDLSFGIQ QGEERIYL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A6e-17564161ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A7e-17370270ATERF1
3gcc_A7e-17370270ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.138490.0bud| fruit| leaf
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Detected in sepals of very young closed buds. Later, expressed in sepals and petals veins and epidermis, as well as in developing gynoecium but not in stamens. At anthesis, confined to the gynoecium, commenced in the anther, and slightly expressed in the anther filament. When petals and sepals withered, strong expression at the bottom of the silique, in the abscission zone, and in the pedicel region below it. At silique maturity, detected in the same region but only at the nectaries. {ECO:0000269|PubMed:15319479}.
UniprotTISSUE SPECIFICITY: Expressed in aerial organs, mostly in flowers, and in roots. Also observed at the branch points of pedicels of most young flowers, and in a patchy pattern in roots of mature plants and very young leaves in the rosette, including support cells of their trichomes. {ECO:0000269|PubMed:15070782, ECO:0000269|PubMed:15319479}.
Functional Description ? help Back to Top
Source Description
UniProtPromotes cuticle formation by inducing the expression of enzymes involved in wax biosynthesis (PubMed:15070782, PubMed:15319479). Confers drought resistance (PubMed:15319479). Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:15070782, ECO:0000269|PubMed:15319479}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGU7324590.0GU732459.1 Malus x domestica AP2 domain class transcription factor (AP2D35) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001315750.11e-174ethylene-responsive transcription factor WIN1-like
SwissprotQ9XI337e-72WIN1_ARATH; Ethylene-responsive transcription factor WIN1
TrEMBLA0A498KEJ11e-171A0A498KEJ1_MALDO; Uncharacterized protein
TrEMBLD5L1191e-173D5L119_MALDO; AP2 domain class transcription factor
STRINGXP_008354369.11e-174(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF57633144
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G15360.11e-72ERF family protein
Publications ? help Back to Top
  1. Taketa S, et al.
    Barley grain with adhering hulls is controlled by an ERF family transcription factor gene regulating a lipid biosynthesis pathway.
    Proc. Natl. Acad. Sci. U.S.A., 2008. 105(10): p. 4062-7
    [PMID:18316719]
  2. Tacken E, et al.
    The role of ethylene and cold temperature in the regulation of the apple POLYGALACTURONASE1 gene and fruit softening.
    Plant Physiol., 2010. 153(1): p. 294-305
    [PMID:20237022]
  3. Al-Abdallat AM,Al-Debei HS,Ayad JY,Hasan S
    Over-expression of SlSHN1 gene improves drought tolerance by increasing cuticular wax accumulation in tomato.
    Int J Mol Sci, 2014. 15(11): p. 19499-515
    [PMID:25350113]
  4. Djemal R,Khoudi H
    Isolation and molecular characterization of a novel WIN1/SHN1 ethylene-responsive transcription factor TdSHN1 from durum wheat (Triticum turgidum. L. subsp. durum).
    Protoplasma, 2015. 252(6): p. 1461-73
    [PMID:25687296]
  5. Sadler C, et al.
    Wax and cutin mutants of Arabidopsis: Quantitative characterization of the cuticular transport barrier in relation to chemical composition.
    Biochim. Biophys. Acta, 2016. 1861(9 Pt B): p. 1336-1344
    [PMID:26965486]
  6. Sajeevan RS, et al.
    Expression of Arabidopsis SHN1 in Indian Mulberry (Morus indica L.) Increases Leaf Surface Wax Content and Reduces Post-harvest Water Loss.
    Front Plant Sci, 2017. 8: p. 418
    [PMID:28421085]