PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000144516
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MIKC_MADS
Protein Properties Length: 266aa    MW: 30008.6 Da    PI: 8.726
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000144516genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF94.64.3e-302171151
                   S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
         SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                   k+ien s rqvtfskRrng+lKKA+ELSvLCdaevavi+fsstgklye+ss
  MDP0000144516 21 KKIENLSSRQVTFSKRRNGLLKKAKELSVLCDAEVAVIVFSSTGKLYEFSS 71
                   68***********************************************96 PP
2K-box52.22.7e-1810119011100
          K-box  11 eakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkklee 100
                      +a +++ +++ L++ei +L+ +  ++ G++L+  slk+Lq+Le+qL +++  +++kK+e+l+e++++++ +e+++ ee ++Lrk+lee
  MDP0000144516 101 VMQATNSNCNVNALQNEIATLRLTCTRMTGKELDGVSLKDLQRLEDQLSEGILCVKDKKEEILMEKLKKSRLQEQKAMEESENLRKELEE 190
                    45667888899***********999**************************************************************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006632.6181373IPR002100Transcription factor, MADS-box
SMARTSM004321.8E-401372IPR002100Transcription factor, MADS-box
CDDcd002651.44E-411484No hitNo description
SuperFamilySSF554552.09E-321487IPR002100Transcription factor, MADS-box
PRINTSPR004047.4E-301535IPR002100Transcription factor, MADS-box
PROSITE patternPS0035001569IPR002100Transcription factor, MADS-box
PfamPF003198.6E-272269IPR002100Transcription factor, MADS-box
PRINTSPR004047.4E-303550IPR002100Transcription factor, MADS-box
PRINTSPR004047.4E-305071IPR002100Transcription factor, MADS-box
PfamPF014861.9E-13103188IPR002487Transcription factor, K-box
PROSITE profilePS5129711104194IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009555Biological Processpollen development
GO:0009910Biological Processnegative regulation of flower development
GO:0048577Biological Processnegative regulation of short-day photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 266 aa     Download sequence    Send to blast
MNTENSTPAR KPLGRGRIEI KKIENLSSRQ VTFSKRRNGL LKKAKELSVL CDAEVAVIVF  60
SSTGKLYEFS STSMDHTLSR YNKGGLIEHP QKERSGDNEP VMQATNSNCN VNALQNEIAT  120
LRLTCTRMTG KELDGVSLKD LQRLEDQLSE GILCVKDKKE EILMEKLKKS RLQEQKAMEE  180
SENLRKELEE MRQNKRSNWP IVVASHPLER RFSCTSSKAV SXYEAEESDH SDTSLHLGLS  240
SDVHRKRKAA KIEHNSNDSG SQVASD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A4e-2213106189MEF2C
5f28_B4e-2213106189MEF2C
5f28_C4e-2213106189MEF2C
5f28_D4e-2213106189MEF2C
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: During the reproductive phase, accumulates in immature buds and at the base of the floral organs, and in the receptacle, ovules, anther filaments, and stigma and style of open flowers. Later observed in sporogenous tissue of anthers. During male gametogenesis, expressed in the microspores before they separate from each other. Later present at high levels within pollen grains up to stage 13 of flower development, when anthers dehisce. During carpel development, first detected in developing ovules. After fertilization, confined to globular structures or nodules of proliferating free nuclear endosperm required for embryo development. Disappears from the endosperm at to the heart stage of embryo development, when very little nuclear endosperm remains. Never detected in developing embryos at any stage. In young seedlings, present everywhere except in a portion of the hypocotyl and in newly emerging leaves. {ECO:0000269|PubMed:11115127, ECO:0000269|PubMed:17521410}.
UniprotTISSUE SPECIFICITY: Mostly expressed in pollen, roots, flowers and siliques, and to a lower extent, in stems and leaves. Expressed in the endosperm and in developing male and female gametophytes. Also present in seedlings. {ECO:0000269|PubMed:11115127, ECO:0000269|PubMed:12837945, ECO:0000269|PubMed:12949148, ECO:0000269|PubMed:16028119, ECO:0000269|PubMed:17521410}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Prevents premature flowering. Downstream regulator of a subset of the MIKC* MADS-controlled genes required during pollen maturation. {ECO:0000269|PubMed:17521410, ECO:0000269|PubMed:18034896, ECO:0000269|PubMed:18799658}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKP1640100.0KP164010.1 Pyrus pyrifolia clone PpAGL18 AGL18 MADS-box protein mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008351603.20.0agamous-like MADS-box protein AGL18
SwissprotQ9M2K81e-66AGL18_ARATH; Agamous-like MADS-box protein AGL18
TrEMBLA0A498I3960.0A0A498I396_MALDO; Uncharacterized protein
STRINGXP_008351603.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF35823260
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G57390.11e-56AGAMOUS-like 18