PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000120013

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 263aa MW: 29484.4 Da PI: 8.0194

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000120013	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.1	0.00029	79	101	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C k F ++ L H++ H MDP0000120013 79 FECQYCFKEFANSQALGGHQNAH 101 89******************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	4.0E-5	75	105	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.51E-6	75	106	No hit	No description
PROSITE profile	PS50157	11.406	79	106	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	81	101	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009736	Biological Process	cytokinin-activated signaling pathway
GO:0009740	Biological Process	gibberellic acid mediated signaling pathway
GO:0010026	Biological Process	trichome differentiation
GO:0048510	Biological Process	regulation of timing of transition from vegetative to reproductive phase
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 263 aa Download sequence Send to blast
MQSETNTVGA CAEKKLRLFG FELNPNRNEE TSMKGGRSAA EGGGDESVNS SNSVSHPIKL 60 ERYRENEKSS TSEPDDKKFE CQYCFKEFAN SQALGGHQNA HKKERMKKKR LQLQARKASI 120 NYYLQPFQTF HHHGSTVAPS WFYDPSSYLN PDHPFTLHEE SQISFNSFDQ SYGPSSGSHS 180 QVSNWYSVPP QQQFPSSQTG EQDHVINPNK FTLTQTDRSG ESRPIVFTPS PLSASTQQSC 240 KPLDLQLGLG VPSKIQRSSR SEA

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.16982	0.0	root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Highly expressed in roots, young leaves, developing stems, branches, inflorescence meristems, floral meristems and siliques. Expressed at low levels in rosette and cauline leaves. {ECO:0000269\|PubMed:21803862, ECO:0000269\|PubMed:22762888}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin (GA). Acts upstream of GIS, GIS2, ZFP8 and the trichome initiation regulators GL1 and GL3 (PubMed:21803862, PubMed:22301962). Binds the promoter region of ZFP8, which may be a direct target of ZPF5 (PubMed:21803862). Is not involved in the regulation of trichome branching (PubMed:22301962). Modulates root hair initiation and elongation in response to cytokinin and ethylene signals by directly promoting expression of the CAPRICE (CPC) gene (PubMed:22762888). {ECO:0000269\|PubMed:21803862, ECO:0000269\|PubMed:22301962, ECO:0000269\|PubMed:22762888}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cytokinin and ethylene. {ECO:0000269\|PubMed:22762888}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008353004.1	0.0	zinc finger protein 5
Swissprot	Q39264	2e-16	ZFP5_ARATH; Zinc finger protein 5
TrEMBL	A0A498HKA1	0.0	A0A498HKA1_MALDO; Uncharacterized protein
STRING	XP_008353004.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF9594	26	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G10480.1	7e-18	zinc finger protein 5

Link Out ? help Back to Top
Phytozome	MDP0000120013

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Savage LJ,Imre KM,Hall DA,Last RL Analysis of essential Arabidopsis nuclear genes encoding plastid-targeted proteins. PLoS ONE, 2013. 8(9): p. e73291 [PMID:24023856] Sun L, et al. GLABROUS INFLORESCENCE STEMS3 (GIS3) regulates trichome initiation and development in Arabidopsis. New Phytol., 2015. 206(1): p. 220-30 [PMID:25640859] Yu D, et al. RPN1a, a subunit of the 26S proteasome, controls trichome development in Arabidopsis. Plant Physiol. Biochem., 2015. 88: p. 82-8 [PMID:25676129] Kim SY,Hyoung S,So WM,Shin JS The novel transcription factor TRP interacts with ZFP5, a trichome initiation-related transcription factor, and negatively regulates trichome initiation through gibberellic acid signaling. Plant Mol. Biol., 2018. 96(3): p. 315-326 [PMID:29335898]