PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10005840
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family E2F/DP
Protein Properties Length: 245aa    MW: 28079.7 Da    PI: 9.9782
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10005840genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP79.72.6e-251291271
      E2F_TDP  2 keksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71
                 +eksL+lltq+f+kl+ +s+e+++tl+++a++L+ +      +++k+RR+YDi+NVL+++nliek     ++++++rw+g
  Lus10005840 12 REKSLWLLTQNFVKLFLSSNEDMITLDTAATALLGDsvnstAMRTKVRRLYDIANVLSSMNLIEKthhpeNRRPAFRWMG 91
                 79***************************************9***********************999999999999997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.3E-23991IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-301191IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.12E-131392IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.0E-201391IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 245 aa     Download sequence    Send to blast
MLILCFDADS KREKSLWLLT QNFVKLFLSS NEDMITLDTA ATALLGDSVN STAMRTKVRR  60
LYDIANVLSS MNLIEKTHHP ENRRPAFRWM GWRGNNGDVD TVKFQTNKRT FGADITNFAS  120
KRNRVDWIDE KENTPGHKRL QEMHRDNHGS KLKQNTEIKS KSFVFGPFSP TGMNKVSSAG  180
NKSTRDIQDV ETLASTCYPQ YCNEAIGELL GHYVEAWKSW HVGVSRRERP ERDRDFQKRL  240
PPPT*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A3e-15883149228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10005840
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021679550.17e-88E2F transcription factor-like E2FF isoform X1
SwissprotQ8RWL02e-62E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A067LLZ13e-86A0A067LLZ1_JATCU; Uncharacterized protein
STRINGLus100058400.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.17e-65DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]