PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa014195
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family MYB
Protein Properties Length: 329aa    MW: 37016.1 Da    PI: 6.5142
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58683555PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-29772PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding57.14.2e-181461148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g+WT+eEd  lv +v+q+G+g+W+ ++   g++R+ k+c++rw +yl
        Lsa014195 14 KGPWTPEEDIMLVSYVQQHGPGNWRQVPTNTGLRRCSKSCRLRWTNYL 61
                     79********************************************97 PP
2Myb_DNA-binding49.41.1e-1567112148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      rg +T++E++ ++++ ++lG++ W++Ia++++  Rt++++k++w+++l
        Lsa014195  67 RGDFTEDEEKMIIQLQALLGNK-WAAIASYLP-ERTDNDIKNYWNTHL 112
                      899*******************.*********.************996 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.603.9E-24564IPR009057Homeodomain-like
PROSITE profilePS5129425.42965IPR017930Myb domain
SuperFamilySSF466891.19E-3111108IPR009057Homeodomain-like
SMARTSM007177.0E-151363IPR001005SANT/Myb domain
PfamPF002492.5E-161461IPR001005SANT/Myb domain
CDDcd001672.37E-111661No hitNo description
Gene3DG3DSA:1.10.10.609.7E-2565117IPR009057Homeodomain-like
SMARTSM007171.0E-1566114IPR001005SANT/Myb domain
PROSITE profilePS5129420.53866116IPR017930Myb domain
PfamPF002495.1E-1567112IPR001005SANT/Myb domain
CDDcd001672.98E-1170111No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 329 aa     Download sequence    Send to blast
MGRPPCCDKL GVKKGPWTPE EDIMLVSYVQ QHGPGNWRQV PTNTGLRRCS KSCRLRWTNY  60
LRPGIRRGDF TEDEEKMIIQ LQALLGNKWA AIASYLPERT DNDIKNYWNT HLKKKLKKLE  120
MGSEDHDLLH TNSKDRFSSS TSSSSSSHCI SRGQWEKRLQ TDIHMAKQAL NDALSIDHKP  180
IFVPQATKSS SHPPAYPSST DNIAKLLKGF MKNSAIYTKT CSNSSTRESS GEVNAPSSES  240
KNNSGIDLSE AFESLFGFDQ SFGSPNNSDF SQSNTSPEGS IFQEESKAEL RFTMFENWLL  300
EETTGGVVDQ GKEDLSNFSF DENPNFFDN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C3e-261411627128MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the DNA sequence 5'-AACAAAC-3' (PubMed:19170933). Acts as a positive regulator of hypersensitive cell death (PubMed:10571865, PubMed:12119395). Acts as a positive regulator of salicylic acid synthesis (PubMed:16730712). Regulates very-long-chain fatty acid biosynthesis (PubMed:18326828). Acts cooperatively with BZR2 to promote expression of a subset of brassinosteroids target genes (PubMed:19170933). Transcriptional activity and hypersensitive response control negatively regulated by PLA2-ALPHA and by the Xanthomonas type III effector XopD (AC G9L9K6) (PubMed:20696912, PubMed:21917550). Involved in the regulation of abscisic acid (ABA) signaling (PubMed:22814374). Increased levels of MYB30 can accelerate flowering both in long and short days through the regulation of FT (PubMed:24587042). {ECO:0000269|PubMed:10571865, ECO:0000269|PubMed:12119395, ECO:0000269|PubMed:16730712, ECO:0000269|PubMed:18326828, ECO:0000269|PubMed:19170933, ECO:0000269|PubMed:20696912, ECO:0000269|PubMed:21917550, ECO:0000269|PubMed:22814374, ECO:0000269|PubMed:24587042}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated during hypersensitive response, but no expression detected during compatible interaction with pathogens (PubMed:10571865). Specifically induced in the inoculated zone 4 hours post pathogen infection (PubMed:20696912). Up-regulated by jasmonic acid and salicylic acid (PubMed:16463103, PubMed:16730712). Transcriptionally regulated by BZR2 (PubMed:19170933). {ECO:0000269|PubMed:10571865, ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:16730712, ECO:0000269|PubMed:19170933, ECO:0000269|PubMed:20696912}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023758366.10.0transcription factor MYB30-like
SwissprotQ9SCU71e-102MYB30_ARATH; Transcription factor MYB30
TrEMBLA0A2J6LQH70.0A0A2J6LQH7_LACSA; Uncharacterized protein
STRINGXP_009765566.11e-125(Nicotiana sylvestris)
STRINGXP_009629125.11e-125(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G28910.11e-103myb domain protein 30
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Kaurilind E,Xu E,Brosché M
    A genetic framework for H2O2 induced cell death in Arabidopsis thaliana.
    BMC Genomics, 2015. 16: p. 837
    [PMID:26493993]
  3. Lee HG,Seo PJ
    The Arabidopsis MIEL1 E3 ligase negatively regulates ABA signalling by promoting protein turnover of MYB96.
    Nat Commun, 2016. 7: p. 12525
    [PMID:27615387]
  4. Serrano I, et al.
    A non canonical subtilase attenuates the transcriptional activation of defence responses in Arabidopsis thaliana.
    Elife, 2017.
    [PMID:27685353]
  5. Liao C,Zheng Y,Guo Y
    MYB30 transcription factor regulates oxidative and heat stress responses through ANNEXIN-mediated cytosolic calcium signaling in Arabidopsis.
    New Phytol., 2017. 216(1): p. 163-177
    [PMID:28726305]
  6. Lee HG,Kim J,Suh MC,Seo PJ
    The MIEL1 E3 Ubiquitin Ligase Negatively Regulates Cuticular Wax Biosynthesis in Arabidopsis Stems.
    Plant Cell Physiol., 2017. 58(7): p. 1249-1259
    [PMID:28838126]
  7. Mabuchi K, et al.
    MYB30 links ROS signaling, root cell elongation, and plant immune responses.
    Proc. Natl. Acad. Sci. U.S.A., 2018. 115(20): p. E4710-E4719
    [PMID:29712840]
  8. Zheng Y,Chen Z,Ma L,Liao C
    The Ubiquitin E3 Ligase RHA2b Promotes Degradation of MYB30 in Abscisic Acid Signaling.
    Plant Physiol., 2018. 178(1): p. 428-440
    [PMID:30030326]