PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa010296
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family ERF
Protein Properties Length: 196aa    MW: 21411.1 Da    PI: 7.1829
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58671355PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-19682PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2491.5e-151411255
        AP2 12 rgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
               +gr++AeIrdp   gk++r++lg+f+taeeAa+a++ a+++++g
  Lsa010296  1 WGRYAAEIRDP---GKKTRVWLGTFDTAEEAARAYDSAARQFRG 41
               9*********8...557************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541711.18E-17150IPR016177DNA-binding domain
PROSITE profilePS5103219.493149IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.107.6E-26149IPR001471AP2/ERF domain
CDDcd000185.96E-28149No hitNo description
SMARTSM003801.2E-24155IPR001471AP2/ERF domain
PfamPF008472.5E-9141IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 196 aa     Download sequence    Send to blast
WGRYAAEIRD PGKKTRVWLG TFDTAEEAAR AYDSAARQFR GAKAKTNFPF PTDLLLPTAV  60
VSGGGMKFLT KTPTESSMVE ASSNSMAPSP GPISTALLPP EALDLSLSHY PLGFPMPHSM  120
FLYHSQMNLH INNNNNHNRL NVFRSDRSVV RDPHLTVGTG GLAQQSDSDS SPVVNFKQEK  180
SLTLDLDLNF PPPEVA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A4e-151542377Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional repressor. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways, and could also regulate other AtERFs. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11487705, ECO:0000269|PubMed:9756931}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by jasmonate (JA) and by Alternaria brassicicola (locally and systemically), but only slightly by ethylene. Strong induction by wounding, cold or drought stress does not require EIN2, whereas induction by NaCl does. Transcripts accumulate in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), and heat stress. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:12805630}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023771297.11e-143ethylene-responsive transcription factor 4
SwissprotO803403e-28ERF78_ARATH; Ethylene-responsive transcription factor 4
TrEMBLA0A2J6KX561e-142A0A2J6KX56_LACSA; Uncharacterized protein
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G44210.13e-20erf domain protein 9
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Cao WH, et al.
    Modulation of ethylene responses affects plant salt-stress responses.
    Plant Physiol., 2007. 143(2): p. 707-19
    [PMID:17189334]
  3. Lyons R, et al.
    The RNA-binding protein FPA regulates flg22-triggered defense responses and transcription factor activity by alternative polyadenylation.
    Sci Rep, 2013. 3: p. 2866
    [PMID:24104185]
  4. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  5. Gao S, et al.
    A cotton miRNA is involved in regulation of plant response to salt stress.
    Sci Rep, 2016. 6: p. 19736
    [PMID:26813144]
  6. Zhou X, et al.
    The ERF11 Transcription Factor Promotes Internode Elongation by Activating Gibberellin Biosynthesis and Signaling.
    Plant Physiol., 2016. 171(4): p. 2760-70
    [PMID:27255484]
  7. Liu W, et al.
    The ethylene response factor AtERF4 negatively regulates the iron deficiency response in Arabidopsis thaliana.
    PLoS ONE, 2017. 12(10): p. e0186580
    [PMID:29045490]