PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa002273

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

bZIP

Protein Properties

Length: 384aa MW: 42540.6 Da PI: 9.9507

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58682820	PU_unref	Unigene	View CDS
PUT-187a-Lactuca_sativa-37628	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	31.8	3.1e-10	228	286	5	63
CHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 5 krerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 kr++r NR +A rs +RK ++ eLe+kv++L++e ++L ++ +l+ l+se+ Lsa002273 228 KRAKRILANRQSAARSKERKIRYTSELERKVQTLQNEATTLSTQVTMLQRDTTGLTSEN 286 9***********************************************99999999887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	1.3E-16	224	288	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	11.128	226	289	IPR004827	Basic-leucine zipper domain
Gene3D	G3DSA:1.20.5.170	4.8E-11	228	283	No hit	No description
Pfam	PF00170	1.0E-8	228	286	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	6.54E-11	228	280	No hit	No description
CDD	cd14703	1.32E-23	229	278	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 384 aa Download sequence Send to blast
MTKTPLPRHR KTRAPIFFLS ISLHGTRSVM PAXSPAAAQK LVLAFMDPKF AGKPIASASY 60 YGGGRMDIEQ MPETPNRGAH HRRAQSETFF RFPDEDILLD DVVADFNFAN IDLPSLSSDA 120 PIPTTTGESS SKSEGESSDV NAVKSTASRP PGPVNHIRSL SVDADFFDGL GLSSAAEASG 180 GYRHRHSNSM DGSAASSFEG DSMLMMLDNS KKALAPDKLA ELALIDPKRA KRILANRQSA 240 ARSKERKIRY TSELERKVQT LQNEATTLST QVTMLQRDTT GLTSENKELK LRLQAMEQQA 300 KLRDALNETL RAEVQRLKIE TGQLPPLNGM NYHHHRSLPP QYSSHQQTFH HFGNQNPQQP 360 PQQQIRPPDA ATNRPPKPTF MDFN

Sequence ? help Back to Top

Protein Sequence Length: 384 aa Download sequence Send to blast

MTKTPLPRHR KTRAPIFFLS ISLHGTRSVM PAXSPAAAQK LVLAFMDPKF AGKPIASASY  60
YGGGRMDIEQ MPETPNRGAH HRRAQSETFF RFPDEDILLD DVVADFNFAN IDLPSLSSDA  120
PIPTTTGESS SKSEGESSDV NAVKSTASRP PGPVNHIRSL SVDADFFDGL GLSSAAEASG  180
GYRHRHSNSM DGSAASSFEG DSMLMMLDNS KKALAPDKLA ELALIDPKRA KRILANRQSA  240
ARSKERKIRY TSELERKVQT LQNEATTLST QVTMLQRDTT GLTSENKELK LRLQAMEQQA  300
KLRDALNETL RAEVQRLKIE TGQLPPLNGM NYHHHRSLPP QYSSHQQTFH HFGNQNPQQP  360
PQQQIRPPDA ATNRPPKPTF MDFN

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds specifically to the VIP1 response elements (VREs) DNA sequence 5'-ACNGCT-3' found in some stress genes (e.g. TRX8 and MYB44), when phosphorylated/activated by MPK3. Required for Agrobacterium VirE2 nuclear import and tumorigenicity. Promotes transient expression of T-DNA in early stages by interacting with VirE2 in complex with the T-DNA and facilitating its translocation to the nucleus, and mediates stable genetic transformation by Agrobacterium by binding H2A histone. Prevents cell differentiation and shoot formation. Limits sulfate utilization efficiency (SUE) and sulfate uptake, especially in low-sulfur conditions. {ECO:0000269\|PubMed:11432846, ECO:0000269\|PubMed:12124400, ECO:0000269\|PubMed:15108305, ECO:0000269\|PubMed:15824315, ECO:0000269\|PubMed:17947581, ECO:0000269\|PubMed:19820165, ECO:0000269\|PubMed:20547563}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transcriptionally activated during the acquisition of pluripotentiality (in protoplasts) by pericentromeric chromatin decondensation and DNA demethylation. Targeted to degradation by the proteasome by VBF and Agrobacterium virF in SCF(VBF) and SCF(virF) E3 ubiquitin ligase complexes after mediating T-DNA translocation to the nucleus. {ECO:0000269\|PubMed:15108305}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023742476.1	0.0	transcription factor VIP1-like
Swissprot	Q9MA75	3e-87	VIP1_ARATH; Transcription factor VIP1
TrEMBL	A0A2J6JWI8	0.0	A0A2J6JWI8_LACSA; Uncharacterized protein
STRING	VIT_18s0076g00330.t01	1e-119	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G43700.1	2e-85	VIRE2-interacting protein 1

Publications ? help Back to Top
Wang Y, et al. The putative Agrobacterium transcriptional activator-like virulence protein VirD5 may target T-complex to prevent the degradation of coat proteins in the plant cell nucleus. New Phytol., 2014. 203(4): p. 1266-81 [PMID:24865527] Xu DB, et al. A G-protein β subunit, AGB1, negatively regulates the ABA response and drought tolerance by down-regulating AtMPK6-related pathway in Arabidopsis. PLoS ONE, 2015. 10(1): p. e0116385 [PMID:25635681] Chen J, et al. ZmbZIP91 regulates expression of starch synthesis-related genes by binding to ACTCAT elements in their promoters. J. Exp. Bot., 2016. 67(5): p. 1327-38 [PMID:26689855] Tsugama D,Liu S,Takano T VIP1 is very important/interesting protein 1 regulating touch responses of Arabidopsis. Plant Signal Behav, 2016. 11(6): p. e1187358 [PMID:27171129] Tsugama D,Liu S,Takano T The bZIP Protein VIP1 Is Involved in Touch Responses in Arabidopsis Roots. Plant Physiol., 2016. 171(2): p. 1355-65 [PMID:27208231] Takeo K,Ito T Subcellular localization of VIP1 is regulated by phosphorylation and 14-3-3 proteins. FEBS Lett., 2017. 591(13): p. 1972-1981 [PMID:28542772] Wang L,Lacroix B,Guo J,Citovsky V The Agrobacterium VirE2 effector interacts with multiple members of the Arabidopsis VIP1 protein family. Mol. Plant Pathol., 2018. 19(5): p. 1172-1183 [PMID:28802023]