PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa002079

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

bZIP

Protein Properties

Length: 711aa MW: 77040.6 Da PI: 6.3892

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-42065	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	39.6	1.1e-12	221	281	2	62
XXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 2 kelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklkse 62 k+ k+ r+++NRe+A+ sRqRKk ++eeLe+kv ++ + ++L ++ e a+l+++ Lsa002079 221 KDEKKKARLIRNRESAQLSRQRKKHYVEELEDKVRAMHSTIQDLNARITYFAAENATLRQQ 281 678999****************************************999999999988876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	5.7E-16	220	284	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	1.8E-11	221	281	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	10.197	222	282	IPR004827	Basic-leucine zipper domain
Gene3D	G3DSA:1.20.5.170	1.9E-15	224	282	No hit	No description
SuperFamily	SSF57959	1.19E-11	224	282	No hit	No description
CDD	cd14704	3.57E-21	225	276	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 711 aa Download sequence Send to blast
MAEEVQAVAD PLASLPIPPL SSSIFSDDLT LPDDFLPYDD GDFDITFDDL HLPSDTEDFF 60 NSAFNPTNPI DLSSSDPEFN DFVSDPETVV AESGNLSEHQ GSDVSGFLNI PSPDNSGKDF 120 LGETVMVLDS LSPESRTENP VSSQGSGNCG SAGSDAAMNC PSPDSGNSVV DQKVKRESGS 180 NFMLKRKKET PEGNSESRTI KYQRSNGTST TTENSNEIDG KDEKKKARLI RNRESAQLSR 240 QRKKHYVEEL EDKVRAMHST IQDLNARITY FAAENATLRQ QMVAGGGGVV CPPPVMYPPH 300 PAMPPMGYPW MPCPPYVVKS QGSQVPLVPI PRLKPQQPTS SQKSKKVEVK KTEATTKTKT 360 KTKKVASISF LGLLLFIVLF GGLVPIMNVK FSGVTDGGFS GVSKDYMFYE QQQQPGRVLM 420 GDDHVNGTNH RTGITNGRAH EHNASEPLVA SLYVPRNDKL VKIDGNLIIH SVLASEKAMA 480 SMEEQGMTKK EDTGLAVALD LVPAISIPKA GRNSGRQPHI YRSSSDHQRI LSSDKEKLKS 540 KHADGKLQQW FREGLAGPML SSGMCTEVFQ FDVSVASASG ALVSATSTAN ITAEDRHNST 600 YITNVKNRRI LHSLPIPLSA TTTTTNITKE QVAGNSSKHE EHHKNNSVSS MVVSVLFDPR 660 EGGDGGGDVE GMMGGAKSFS RIFVVVLLDS VKYVTYSCML PLKGASHLVT A

Sequence ? help Back to Top

Protein Sequence Length: 711 aa Download sequence Send to blast

MAEEVQAVAD PLASLPIPPL SSSIFSDDLT LPDDFLPYDD GDFDITFDDL HLPSDTEDFF  60
NSAFNPTNPI DLSSSDPEFN DFVSDPETVV AESGNLSEHQ GSDVSGFLNI PSPDNSGKDF  120
LGETVMVLDS LSPESRTENP VSSQGSGNCG SAGSDAAMNC PSPDSGNSVV DQKVKRESGS  180
NFMLKRKKET PEGNSESRTI KYQRSNGTST TTENSNEIDG KDEKKKARLI RNRESAQLSR  240
QRKKHYVEEL EDKVRAMHST IQDLNARITY FAAENATLRQ QMVAGGGGVV CPPPVMYPPH  300
PAMPPMGYPW MPCPPYVVKS QGSQVPLVPI PRLKPQQPTS SQKSKKVEVK KTEATTKTKT  360
KTKKVASISF LGLLLFIVLF GGLVPIMNVK FSGVTDGGFS GVSKDYMFYE QQQQPGRVLM  420
GDDHVNGTNH RTGITNGRAH EHNASEPLVA SLYVPRNDKL VKIDGNLIIH SVLASEKAMA  480
SMEEQGMTKK EDTGLAVALD LVPAISIPKA GRNSGRQPHI YRSSSDHQRI LSSDKEKLKS  540
KHADGKLQQW FREGLAGPML SSGMCTEVFQ FDVSVASASG ALVSATSTAN ITAEDRHNST  600
YITNVKNRRI LHSLPIPLSA TTTTTNITKE QVAGNSSKHE EHHKNNSVSS MVVSVLFDPR  660
EGGDGGGDVE GMMGGAKSFS RIFVVVLLDS VKYVTYSCML PLKGASHLVT A

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in salt and osmotic stress responses. Functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes (PubMed:17662035). Functions as a stress sensor and transducer in ER stress signaling pathway. ER stress induces proteolysis of BZIP17 by SBT6.1 (S1P) and S2P, and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones, as well as protein involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269\|PubMed:17662035, ECO:0000269\|PubMed:20876872}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023743602.1	0.0	bZIP transcription factor 17-like
Swissprot	O22208	1e-165	BZP17_ARATH; bZIP transcription factor 17
TrEMBL	A0A2J6JU41	0.0	A0A2J6JU41_LACSA; Uncharacterized protein
STRING	VIT_08s0040g00870.t01	0.0	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G40950.1	1e-125	bZIP family protein

Publications ? help Back to Top
Zhou SF, et al. Membrane-associated transcription factor peptidase, site-2 protease, antagonizes ABA signaling in Arabidopsis. New Phytol., 2015. 208(1): p. 188-97 [PMID:25919792] Sagor GH, et al. The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis. Front Plant Sci, 2015. 6: p. 687 [PMID:26442007] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Kim JS,Yamaguchi-Shinozaki K,Shinozaki K ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation. Plant Physiol., 2018. 176(3): p. 2221-2230 [PMID:29367234] Cifuentes-Esquivel N, et al. bZIP17 regulates the expression of genes related to seed storage and germination, reducing seed susceptibility to osmotic stress. J. Cell. Biochem., 2018. 119(8): p. 6857-6868 [PMID:29693271] Guan P, et al. SENSITIVE TO SALT1, An Endoplasmic Reticulum-Localized Chaperone, Positively Regulates Salt Resistance. Plant Physiol., 2018. 178(3): p. 1390-1405 [PMID:30287478]