PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lj4g3v2313500.1
Organism
Lotus japonicus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Loteae; Lotus
Family C2H2
Protein Properties Length: 375aa    MW: 42642.4 Da    PI: 6.6249
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lj4g3v2313500.1genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.0005181103323
                      ET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                      C+   Cgk+F +   L++H   H
  Lj4g3v2313500.1  81 CSyeGCGKTFIDAGALRKHSHIH 103
                      77779**************7766 PP
2zf-C2H214.97.6e-05108132123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      + C+   Cgk F ++s LkrH   H
  Lj4g3v2313500.1 108 FICHyeGCGKKFLDSSKLKRHFLIH 132
                      78*******************8877 PP
3zf-C2H221.75.4e-07138162123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      ++Cp   Cgk Fs   nL++H++tH
  Lj4g3v2313500.1 138 FVCPheGCGKAFSLDFNLRSHMKTH 162
                      89**********************9 PP
4zf-C2H215.74.2e-05168192123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      + Cp  dCgk++ + + Lk+H  +H
  Lj4g3v2313500.1 168 HICPypDCGKRYAHEYKLKNHVASH 192
                      679999****************996 PP
5zf-C2H2130.00031232257123
                      EEET..TTTEEESSHHHHHHHHHH.T CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                      y Cp   C k + + + Lk H+++ H
  Lj4g3v2313500.1 232 YACPyeGCEKAYIHEYKLKLHLKReH 257
                      89*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.609.3E-1474105IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.003279103IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.74179108IPR007087Zinc finger, C2H2
PROSITE patternPS00028081103IPR007087Zinc finger, C2H2
SuperFamilySSF576675.19E-882132No hitNo description
Gene3DG3DSA:3.30.160.604.5E-14106128IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0052108132IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.63108137IPR007087Zinc finger, C2H2
PROSITE patternPS000280110132IPR007087Zinc finger, C2H2
SuperFamilySSF576675.12E-14119171No hitNo description
Gene3DG3DSA:3.30.160.603.6E-20129162IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.695138167IPR007087Zinc finger, C2H2
SMARTSM003553.1E-4138162IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280140162IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.9E-9163194IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.616168197IPR007087Zinc finger, C2H2
SMARTSM003550.0037168192IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280170193IPR007087Zinc finger, C2H2
SuperFamilySSF576672.09E-5227255No hitNo description
Gene3DG3DSA:3.30.160.606.5E-9228254IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.66232262IPR007087Zinc finger, C2H2
SMARTSM003550.012232257IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280234257IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 375 aa     Download sequence    Send to blast
METTHFNHST LFDRRPFLKS KAPAVRWVKE WVPQDVLATG GKCMLLRWVA EDTLKASKEK  60
ENEPSGPEPE PEPTTEVLFL CSYEGCGKTF IDAGALRKHS HIHGERQFIC HYEGCGKKFL  120
DSSKLKRHFL IHTGERDFVC PHEGCGKAFS LDFNLRSHMK THSQENYHIC PYPDCGKRYA  180
HEYKLKNHVA SHHEKNPSLE LPKYTTPPSE KQTKTTKPSG GAYTSASSDR PYACPYEGCE  240
KAYIHEYKLK LHLKREHPGH MSEENAVHAL ANADNEMDEA SDQDAYGGVK RSNGKSQKQS  300
KPKPNLKLPP SKMARKGSAP TPSAPLNVIK KPWPVKQETY DEDSEETEED RDNVEDGWRY  360
AGNNEDDDEE TEDED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C4e-34811928119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Lja.94170.0cell culture| floral bud| root
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269|PubMed:26961720}.
UniprotTISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269|PubMed:26961720}.
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLj4g3v2313500.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT1492820.0BT149282.1 Lotus japonicus clone JCVI-FLLj-21L8 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027334846.10.0zinc finger transcription factor YY1 isoform X1
SwissprotQ2V3L31e-157YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLI3T9840.0I3T984_LOTJA; Uncharacterized protein
STRINGXP_004485467.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-141C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]