PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kaladp0192s0039.1.p

Organism

Kalanchoe laxiflora

Taxonomic ID

1670617

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

NAC

Protein Properties

Length: 372aa MW: 40941.2 Da PI: 8.4545

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kaladp0192s0039.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	179.3	1e-55	49	177	1	129
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdk 90 lppGfrFhPtdeel+++yL kkv ++++++ ++i+evd++k+ePw+Lp+k++ +ekewyfFs rd+ky+tg r+nrat++gyWkatgkd+ Kaladp0192s0039.1.p 49 LPPGFRFHPTDEELITYYLIKKVLDSNFTA-RAIAEVDLNKCEPWELPEKARMGEKEWYFFSLRDRKYPTGLRTNRATEAGYWKATGKDR 137 79***********************999.89***********99999********************************* PP NAM 91 evlsk.kgelvglkktLvfykgrapkgektdWvmheyrle 129 e++s+ + +lvg+kktLvfy+grapkgek++Wvmheyrle Kaladp0192s0039.1.p 138 EICSSkTLSLVGMKKTLVFYRGRAPKGEKSNWVMHEYRLE 177 9745567***************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	7.32E-63	45	201	IPR003441	NAC domain
PROSITE profile	PS51005	59.747	49	201	IPR003441	NAC domain
Pfam	PF02365	1.9E-28	50	176	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010072	Biological Process	primary shoot apical meristem specification
GO:0010160	Biological Process	formation of organ boundary
GO:0010223	Biological Process	secondary shoot formation
GO:0048366	Biological Process	leaf development
GO:0048504	Biological Process	regulation of timing of organ formation
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 372 aa Download sequence Send to blast
MMDMMMMMKM MGYSSNQNNY HQHTHGDSNS TACTMVGADI ISSSSSATLP PGFRFHPTDE 60 ELITYYLIKK VLDSNFTARA IAEVDLNKCE PWELPEKARM GEKEWYFFSL RDRKYPTGLR 120 TNRATEAGYW KATGKDREIC SSKTLSLVGM KKTLVFYRGR APKGEKSNWV MHEYRLEGKF 180 AYHFLSRSSK DEWVISRVFQ KTGVGLVSTS TTSTTGNKQK PPNRHHQEVS SASSASLPPL 240 LNPDISSGES FAAKTAAAAQ QQHVSCFSTM AAHPAASYIS SDFPPAAVEG GAAAASASAY 300 NCVFPSLRSL QENLNFPNFF FPAPSSCVHG GIGEMMEISG GGSWQQQLLG EKRKIVGGTE 360 LDCLWTSNYS Q*

Sequence ? help Back to Top

Protein Sequence Length: 372 aa Download sequence Send to blast

MMDMMMMMKM MGYSSNQNNY HQHTHGDSNS TACTMVGADI ISSSSSATLP PGFRFHPTDE  60
ELITYYLIKK VLDSNFTARA IAEVDLNKCE PWELPEKARM GEKEWYFFSL RDRKYPTGLR  120
TNRATEAGYW KATGKDREIC SSKTLSLVGM KKTLVFYRGR APKGEKSNWV MHEYRLEGKF  180
AYHFLSRSSK DEWVISRVFQ KTGVGLVSTS TTSTTGNKQK PPNRHHQEVS SASSASLPPL  240
LNPDISSGES FAAKTAAAAQ QQHVSCFSTM AAHPAASYIS SDFPPAAVEG GAAAASASAY  300
NCVFPSLRSL QENLNFPNFF FPAPSSCVHG GIGEMMEISG GGSWQQQLLG EKRKIVGGTE  360
LDCLWTSNYS Q*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	8e-53	45	201	13	165	NO APICAL MERISTEM PROTEIN
1ut4_B	8e-53	45	201	13	165	NO APICAL MERISTEM PROTEIN
1ut7_A	8e-53	45	201	13	165	NO APICAL MERISTEM PROTEIN
1ut7_B	8e-53	45	201	13	165	NO APICAL MERISTEM PROTEIN
4dul_A	8e-53	45	201	13	165	NAC domain-containing protein 19
4dul_B	8e-53	45	201	13	165	NAC domain-containing protein 19
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator of STM and KNAT6. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for the fusion of septa of gynoecia along the length of the ovaries. Activates the shoot formation in callus in a STM-dependent manner. Controls leaf margin development and required for leaf serration. Involved in axillary meristem initiation and separation of the meristem from the main stem. Regulates the phyllotaxy throughout the plant development. Seems to act as an inhibitor of cell division. {ECO:0000269\|PubMed:10079219, ECO:0000269\|PubMed:10750709, ECO:0000269\|PubMed:12163400, ECO:0000269\|PubMed:12492830, ECO:0000269\|PubMed:12610213, ECO:0000269\|PubMed:15202996, ECO:0000269\|PubMed:15294871, ECO:0000269\|PubMed:15500463, ECO:0000269\|PubMed:15723790, ECO:0000269\|PubMed:16798887, ECO:0000269\|PubMed:17098808, ECO:0000269\|PubMed:17122068, ECO:0000269\|PubMed:17251269, ECO:0000269\|PubMed:17287247, ECO:0000269\|PubMed:9212461}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00562	DAP	Transfer from AT5G53950	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By BRM and SYD, at the chromatin level, and conferring a very specific spatial expression pattern. Precise spatial regulation by post-transcriptional repression directed by the microRNA miR164. {ECO:0000269\|PubMed:15202996, ECO:0000269\|PubMed:15294871, ECO:0000269\|PubMed:15723790, ECO:0000269\|PubMed:16854978, ECO:0000269\|PubMed:17251269, ECO:0000269\|PubMed:17287247}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016579532.1	1e-129	PREDICTED: protein CUP-SHAPED COTYLEDON 2-like
Swissprot	O04017	1e-105	NAC98_ARATH; Protein CUP-SHAPED COTYLEDON 2
TrEMBL	A0A1U8H7V7	1e-128	A0A1U8H7V7_CAPAN; protein CUP-SHAPED COTYLEDON 2-like
STRING	XP_009615029.1	1e-125	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G53950.1	1e-100	NAC family protein

Link Out ? help Back to Top
Phytozome	Kaladp0192s0039.1.p

Publications ? help Back to Top
Wang YX Characterization of a novel Medicago sativa NAC transcription factor gene involved in response to drought stress. Mol. Biol. Rep., 2013. 40(11): p. 6451-8 [PMID:24057250] Kamiuchi Y,Yamamoto K,Furutani M,Tasaka M,Aida M The CUC1 and CUC2 genes promote carpel margin meristem formation during Arabidopsis gynoecium development. Front Plant Sci, 2014. 5: p. 165 [PMID:24817871] Gonçalves B, et al. A conserved role for CUP-SHAPED COTYLEDON genes during ovule development. Plant J., 2015. 83(4): p. 732-42 [PMID:26119568] Du Q,Wang H The role of HD-ZIP III transcription factors and miR165/166 in vascular development and secondary cell wall formation. Plant Signal Behav, 2015. 10(10): p. e1078955 [PMID:26340415] Vialette-Guiraud AC, et al. A Conserved Role for the NAM/miR164 Developmental Module Reveals a Common Mechanism Underlying Carpel Margin Fusion in Monocarpous and Syncarpous Eurosids. Front Plant Sci, 2015. 6: p. 1239 [PMID:26793217] Cui X, et al. REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulate organ boundary formation in Arabidopsis. Nat. Genet., 2016. 48(6): p. 694-9 [PMID:27111035] Blein T,Pautot V,Laufs P Combinations of Mutations Sufficient to Alter Arabidopsis Leaf Dissection. Plants (Basel), 2013. 2(2): p. 230-47 [PMID:27137374] Biot E, et al. Multiscale quantification of morphodynamics: MorphoLeaf software for 2D shape analysis. Development, 2016. 143(18): p. 3417-28 [PMID:27387872] Zheng M, et al. Chloroplast Translation Initiation Factors Regulate Leaf Variegation and Development. Plant Physiol., 2016. 172(2): p. 1117-1130 [PMID:27535792] Balkunde R,Kitagawa M,Xu XM,Wang J,Jackson D SHOOT MERISTEMLESS trafficking controls axillary meristem formation, meristem size and organ boundaries in Arabidopsis. Plant J., 2017. 90(3): p. 435-446 [PMID:28161901] Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] González-Carranza ZH, et al. HAWAIIAN SKIRT controls size and floral organ number by modulating CUC1 and CUC2 expression. PLoS ONE, 2017. 12(9): p. e0185106 [PMID:28934292] Wilson-Sánchez D,Martínez-López S,Navarro-Cartagena S,Jover-Gil S,Micol JL Members of the DEAL subfamily of the DUF1218 gene family are required for bilateral symmetry but not for dorsoventrality in Arabidopsis leaves. New Phytol., 2018. 217(3): p. 1307-1321 [PMID:29139551] Gonçalves B, et al. GDP-L-fucose is required for boundary definition in plants. J. Exp. Bot., 2017. 68(21-22): p. 5801-5811 [PMID:29186469] Sha S, et al. To be serrate or pinnate: diverse leaf forms of yarrows (Achillea) are linked to differential expression patterns of NAM genes. Ann. Bot., 2018. 121(2): p. 255-266 [PMID:29267935] Maugarny-Calès A, et al. Dissecting the pathways coordinating patterning and growth by plant boundary domains. PLoS Genet., 2019. 15(1): p. e1007913 [PMID:30677017]