PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

WALNUT_00018866-RA

Organism

Juglans regia

Taxonomic ID

51240

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans

Family

NAC

Protein Properties

Length: 1098aa MW: 122731 Da PI: 4.9001

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
WALNUT_00018866-RA	genome	JHU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	167.2	5.6e-52	55	182	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkd 89 l+pGfrFhPtdeelv +yLk+kv+gk++++ ++i+evdiyk+ePwdL k +k++++ewyfFs dkky +g r nrat++gyWkatg+d WALNUT_00018866-RA 55 LAPGFRFHPTDEELVIYYLKRKVSGKRFQI-NAISEVDIYKSEPWDLAgKsGLKTRDQEWYFFSALDKKYGNGARMNRATSKGYWKATGND 144 579*************************.89**********85347788999***************************** PP NAM 90 kevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 +e+ + +++ vglkktLvf+ grap g++t+Wvmheyrl WALNUT_00018866-RA 145 REIRH-GSKIVGLKKTLVFHVGRAPVGVRTNWVMHEYRL 182 *.99***************************98 PP
2	NAM	167.3	5.2e-52	554	681	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkd 89 l+pGfrFhPtdeelv +yLk+kv+gk++++ + i+ +diyk+ePwdLp k k+k+++ ewyfFs d+ky +++r+nrat+ gyWk+tgkd WALNUT_00018866-RA 554 LAPGFRFHPTDEELVRYYLKRKVSGKPFRF-DPISVIDIYKSEPWDLPiKsKLKSRDLEWYFFSALDRKYGNSSRTNRATEMGYWKTTGKD 643 579************************9.99**********96347777888***************************** PP NAM 90 kevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 ++v + ++++vg+kktLv+++grap+g +t+Wvmheyrl WALNUT_00018866-RA 644 RTVRQ-NSRAVGMKKTLVYHSGRAPHGARTNWVMHEYRL 681 9.999**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	5.23E-60	51	208	IPR003441	NAC domain
PROSITE profile	PS51005	58.126	55	207	IPR003441	NAC domain
Pfam	PF02365	2.6E-26	57	182	IPR003441	NAC domain
SuperFamily	SSF101941	3.01E-59	547	704	IPR003441	NAC domain
PROSITE profile	PS51005	56.866	554	704	IPR003441	NAC domain
Pfam	PF02365	1.5E-27	556	681	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009819	Biological Process	drought recovery
GO:0010150	Biological Process	leaf senescence
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:2000377	Biological Process	regulation of reactive oxygen species metabolic process
GO:0005634	Cellular Component	nucleus
GO:0005737	Cellular Component	cytoplasm
GO:0005886	Cellular Component	plasma membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 1098 aa Download sequence Send to blast
MTTYAFVSSA SLKGVIPCQP PKTLASVSYR GPTISTMGRD TSPVPATPAT APTYLAPGFR 60 FHPTDEELVI YYLKRKVSGK RFQINAISEV DIYKSEPWDL AGKSGLKTRD QEWYFFSALD 120 KKYGNGARMN RATSKGYWKA TGNDREIRHG SKIVGLKKTL VFHVGRAPVG VRTNWVMHEY 180 RLVEEELEKA RVGVTQDAYV LCRVFHKNNI GPPNSHRYAP FIEEEWDDGI PAFLPGEEAR 240 IQVVADPDSH AKEASHDARV KEAGLGAFVE GNSHSAYVEN YGECVENRQD SFVEGNNFEQ 300 DTRSINDAPP GSANEVPRDS QIASVDCKSE RIDDCPSLSM ANPRPPLIYK RRRHCESNSN 360 HSNVSETSTR ISQDHCSSTT TTEATALTMT TSTTMTTAAP RNFLSALVEY SLLESIDPKD 420 SLSVSPPFDP ANLGSSVPPS CLKFIQELQN ELHKISVERE TLKFETMSAQ TMIRILQSRI 480 EHLNKENEDL RKSIGDAKDQ TDQGRKHGQS AQEYVDVENN MIKVCWKVFA MTLQSVLLER 540 EGSNSMGLHS ETSLAPGFRF HPTDEELVRY YLKRKVSGKP FRFDPISVID IYKSEPWDLP 600 IKSKLKSRDL EWYFFSALDR KYGNSSRTNR ATEMGYWKTT GKDRTVRQNS RAVGMKKTLV 660 YHSGRAPHGA RTNWVMHEYR LVDEELEKTG IAIDSFVLCR VFQKSGTGPK NGEHYGAPFI 720 EEEWEEDDVA AFLPCEEAAV DDVVVGDGAC VEAIELDQDL EISNPSESTP PPLNFYYGDT 780 SNDVEQYEDF VEDCQKPIMG SGETFELCHD EKLVDIPEQY EMDMKPIKDE FFVESSRIMK 840 PSEVNYSLDE PYLDATDNPL LGDGFFLESD DLLNPVESDA AGFDMLDEYL TFLNADDDMA 900 FDPSEIMGGE NSFSNQATHT QEHLNGGTEK VYIDGQQPSE AQGSNDASTS KQKPEAAIYE 960 SDIKNPFIKH ATRMLGSIPA PPAYASEFPA KDVTLQLHSA AQSSSSVHVT TGVIRIRNTT 1020 LTSHGTDWLL GKNSDVNFGM PFLLPQGDTN SANLVPMAGL HAAGKTASVV SWGWFFLIFF 1080 WALILSVSFR FASNIYIK

Sequence ? help Back to Top

Protein Sequence Length: 1098 aa Download sequence Send to blast

MTTYAFVSSA SLKGVIPCQP PKTLASVSYR GPTISTMGRD TSPVPATPAT APTYLAPGFR  60
FHPTDEELVI YYLKRKVSGK RFQINAISEV DIYKSEPWDL AGKSGLKTRD QEWYFFSALD  120
KKYGNGARMN RATSKGYWKA TGNDREIRHG SKIVGLKKTL VFHVGRAPVG VRTNWVMHEY  180
RLVEEELEKA RVGVTQDAYV LCRVFHKNNI GPPNSHRYAP FIEEEWDDGI PAFLPGEEAR  240
IQVVADPDSH AKEASHDARV KEAGLGAFVE GNSHSAYVEN YGECVENRQD SFVEGNNFEQ  300
DTRSINDAPP GSANEVPRDS QIASVDCKSE RIDDCPSLSM ANPRPPLIYK RRRHCESNSN  360
HSNVSETSTR ISQDHCSSTT TTEATALTMT TSTTMTTAAP RNFLSALVEY SLLESIDPKD  420
SLSVSPPFDP ANLGSSVPPS CLKFIQELQN ELHKISVERE TLKFETMSAQ TMIRILQSRI  480
EHLNKENEDL RKSIGDAKDQ TDQGRKHGQS AQEYVDVENN MIKVCWKVFA MTLQSVLLER  540
EGSNSMGLHS ETSLAPGFRF HPTDEELVRY YLKRKVSGKP FRFDPISVID IYKSEPWDLP  600
IKSKLKSRDL EWYFFSALDR KYGNSSRTNR ATEMGYWKTT GKDRTVRQNS RAVGMKKTLV  660
YHSGRAPHGA RTNWVMHEYR LVDEELEKTG IAIDSFVLCR VFQKSGTGPK NGEHYGAPFI  720
EEEWEEDDVA AFLPCEEAAV DDVVVGDGAC VEAIELDQDL EISNPSESTP PPLNFYYGDT  780
SNDVEQYEDF VEDCQKPIMG SGETFELCHD EKLVDIPEQY EMDMKPIKDE FFVESSRIMK  840
PSEVNYSLDE PYLDATDNPL LGDGFFLESD DLLNPVESDA AGFDMLDEYL TFLNADDDMA  900
FDPSEIMGGE NSFSNQATHT QEHLNGGTEK VYIDGQQPSE AQGSNDASTS KQKPEAAIYE  960
SDIKNPFIKH ATRMLGSIPA PPAYASEFPA KDVTLQLHSA AQSSSSVHVT TGVIRIRNTT  1020
LTSHGTDWLL GKNSDVNFGM PFLLPQGDTN SANLVPMAGL HAAGKTASVV SWGWFFLIFF  1080
WALILSVSFR FASNIYIK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	7e-47	55	710	13	171	NO APICAL MERISTEM PROTEIN
1ut4_B	7e-47	55	710	13	171	NO APICAL MERISTEM PROTEIN
1ut7_A	7e-47	55	710	13	171	NO APICAL MERISTEM PROTEIN
1ut7_B	7e-47	55	710	13	171	NO APICAL MERISTEM PROTEIN
3swm_A	7e-47	55	710	16	174	NAC domain-containing protein 19
3swm_B	7e-47	55	710	16	174	NAC domain-containing protein 19
3swm_C	7e-47	55	710	16	174	NAC domain-containing protein 19
3swm_D	7e-47	55	710	16	174	NAC domain-containing protein 19
3swp_A	7e-47	55	710	16	174	NAC domain-containing protein 19
3swp_B	7e-47	55	710	16	174	NAC domain-containing protein 19
3swp_C	7e-47	55	710	16	174	NAC domain-containing protein 19
3swp_D	7e-47	55	710	16	174	NAC domain-containing protein 19
4dul_A	7e-47	55	710	13	171	NAC domain-containing protein 19
4dul_B	7e-47	55	710	13	171	NAC domain-containing protein 19
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (Ref.6, PubMed:24323506, PubMed:25219309). Promotes reactive oxygen species (ROS) production during drought-induced leaf senescence. In response to abscisic acid (ABA)-mediated drought stress signals, binds directly to the promoters of RBOHC and RBOHE genes, encoding ROS biosynthetic enzymes, resulting in ROS accumulation and triggering leaf senescence via programmed cell death (PCD). ROS-induced leaf senescence sustains plant survival under drought conditions (PubMed:22313226). Involved in heat stress response. Modulates PCD through a ROS-mediated positive feedback control under heat stress conditions. This may provide an adaptation strategy for plant survival under extreme heat stress conditions (PubMed:25219309). Acts as repressor in preventing anther dehiscence during stamen development by suppressing genes that participate in jasmonic acid (JA) biosynthesis, such as DAD1, AOS, AOC3, OPR3 and 4CLL5/OPCL1 (PubMed:24323506). {ECO:0000269\|PubMed:22313226, ECO:0000269\|PubMed:24323506, ECO:0000269\|PubMed:25219309, ECO:0000269\|Ref.6}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00343	DAP	Transfer from AT3G10500	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA) (PubMed:22313226, PubMed:25219309). Induced by heat shock (PubMed:25219309). Induced by cold, drought stress and methyl methanesulfonate (MMS) treatment (PubMed:17158162). {ECO:0000269\|PubMed:17158162, ECO:0000269\|PubMed:22313226, ECO:0000269\|PubMed:25219309}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018848042.1	0.0	PREDICTED: NAC domain-containing protein 53-like
Swissprot	Q949N0	1e-150	NAC53_ARATH; NAC domain-containing protein 53
TrEMBL	A0A2I4GVX6	0.0	A0A2I4GVX6_JUGRE; NAC domain-containing protein 53-like
STRING	VIT_13s0019g05240.t01	0.0	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5347	32	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10500.1	1e-131	NAC domain containing protein 53

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Gladman NP,Marshall RS,Lee KH,Vierstra RD The Proteasome Stress Regulon Is Controlled by a Pair of NAC Transcription Factors in Arabidopsis. Plant Cell, 2016. 28(6): p. 1279-96 [PMID:27194708] Sanz-Fernández M, et al. Screening Arabidopsis mutants in genes useful for phytoremediation. J. Hazard. Mater., 2017. 335: p. 143-151 [PMID:28441590]