PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

HL.SW.v1.0.G004466.1

Organism

Humulus lupulus

Taxonomic ID

3486

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

ERF

Protein Properties

Length: 235aa MW: 25368.2 Da PI: 9.8707

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G004466.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	60.4	4.1e-19	5	55	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr..krfslgkfgtaeeAakaaiaarkkleg 55 ++++GVr+++ +g+WvAeIr+p +r++lg+f tae+Aa+a+++a+ ++g HL.SW.v1.0.G004466.1 5 KKFRGVRQRH-WGSWVAEIRHP-----LlkRRVWLGTFETAEDAARAYDEAAVLMNG 55 59*****9.******8.....334*******************977765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	6.36E-33	5	64	No hit	No description
Gene3D	G3DSA:3.30.730.10	7.5E-33	6	63	IPR001471	AP2/ERF domain
Pfam	PF00847	6.7E-12	6	51	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.77E-20	6	64	IPR016177	DNA-binding domain
PROSITE profile	PS51032	22.194	6	63	IPR001471	AP2/ERF domain
SMART	SM00380	1.0E-38	6	69	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.7E-10	7	18	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.7E-10	29	45	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 235 aa Download sequence Send to blast
MVQPKKFRGV RQRHWGSWVA EIRHPLLKRR VWLGTFETAE DAARAYDEAA VLMNGRNAKT 60 NFPVPDQITA AASATATSAE QDRNNNTNNK ASALSELLKS KLRKCGLKTP SSRSLTCLRL 120 DTESCCIGVW QKRGGSGGGG YQRSDTKNNN NISNTSSNAS TTTATTTPQK DNSKWVLTIE 180 FGKVMNGGGC GQRGSSSEST SPAAFEEGGS SRSTQEEENR AALQMIEELL MSTN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	1e-16	5	64	1	61	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Promotes cuticle formation by inducing the expression of enzymes involved in wax biosynthesis (PubMed:15070782, PubMed:15319479). Confers drought resistance (PubMed:15319479). Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:15070782, ECO:0000269\|PubMed:15319479}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009381116.1	2e-63	PREDICTED: ethylene-responsive transcription factor WIN1-like
Swissprot	Q9XI33	4e-62	WIN1_ARATH; Ethylene-responsive transcription factor WIN1
TrEMBL	A0A2P5EU15	1e-80	A0A2P5EU15_TREOI; AP2/ERF transcription factor
STRING	XP_002524500.1	9e-62	(Ricinus communis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF576	33	144

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G15360.1	9e-46	ERF family protein

Publications ? help Back to Top
Taketa S, et al. Barley grain with adhering hulls is controlled by an ERF family transcription factor gene regulating a lipid biosynthesis pathway. Proc. Natl. Acad. Sci. U.S.A., 2008. 105(10): p. 4062-7 [PMID:18316719] Al-Abdallat AM,Al-Debei HS,Ayad JY,Hasan S Over-expression of SlSHN1 gene improves drought tolerance by increasing cuticular wax accumulation in tomato. Int J Mol Sci, 2014. 15(11): p. 19499-515 [PMID:25350113] Djemal R,Khoudi H Isolation and molecular characterization of a novel WIN1/SHN1 ethylene-responsive transcription factor TdSHN1 from durum wheat (Triticum turgidum. L. subsp. durum). Protoplasma, 2015. 252(6): p. 1461-73 [PMID:25687296] Sadler C, et al. Wax and cutin mutants of Arabidopsis: Quantitative characterization of the cuticular transport barrier in relation to chemical composition. Biochim. Biophys. Acta, 2016. 1861(9 Pt B): p. 1336-1344 [PMID:26965486] Sajeevan RS, et al. Expression of Arabidopsis SHN1 in Indian Mulberry (Morus indica L.) Increases Leaf Surface Wax Content and Reduces Post-harvest Water Loss. Front Plant Sci, 2017. 8: p. 418 [PMID:28421085]