PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gorai.010G067000.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family GRAS
Protein Properties Length: 478aa    MW: 52482.4 Da    PI: 4.9721
Description GRAS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gorai.010G067000.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GRAS416.82e-1271004651374
                GRAS   1 lvelLlecAeavssgdlelaqalLarlselaspdg..dpmqRlaayfteALaarlar.svselykalppsetseknsseelaalklfsevs 88 
                         lv+ L++cAe+v+sgdl+la++l+  ++ l +       + ++a +f  AL++r+++ ++ + +        +  +  e+   ++ f+e++
  Gorai.010G067000.1 100 LVHMLMTCAECVQSGDLSLATSLIDDMQGLLTHVNtvCGIGKVAGHFIDALSRRIFQgMGGGSV--------NGGSAFENEILYHHFYEAC 182
                         689*************************99555551369*****************92222222........22224455567899***** PP

                GRAS  89 PilkfshltaNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAeelgvpfefn 179
                         P+lkf+h+taNqaIlea++g+++vH++Df++++GlQWpaL+qaLa Rp+gpp lR+Tg+g+p+++ +++l+e+g rLa++A++++v+f f+
  Gorai.010G067000.1 183 PYLKFAHFTANQAILEAFDGHDCVHVVDFNLMHGLQWPALIQALALRPGGPPLLRLTGIGPPSPDGRDSLREIGLRLAELARSVNVRFAFR 273
                         ******************************************************************************************* PP

                GRAS 180 vlvakrledleleeLrvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfds 270
                          ++a+rled+++++L+v+p+Ea+aVn+++qlhrll  +++ +s++d+vL+ +++l+Pk+++vveqea+hn++ Fl+rf+eal+yys++fds
  Gorai.010G067000.1 274 GVAASRLEDVKPWMLQVNPKEAVAVNSIMQLHRLLGCEQTRDSPIDTVLSWIRGLNPKIMTVVEQEANHNQPGFLDRFTEALYYYSTMFDS 364
                         ******************************************************************************************* PP

                GRAS 271 leaklpreseerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvksdgyrveeesgslvlg 361
                         lea      + ++ + + +++rei nvv+ceg++r+erhe l+kWr+rl+ aGF++++l+++a kqa++ll  ++ +gy+vee++g+l lg
  Gorai.010G067000.1 365 LEAC---RIQPEKALAEIYIQREIGNVVSCEGSARVERHEPLAKWRRRLSGAGFRALRLGSNAFKQASMLLTLFSAEGYSVEENEGCLSLG 452
                         *999...446666677778************************************************************************ PP

                GRAS 362 WkdrpLvsvSaWr 374
                         W++ pL+++SaW+
  Gorai.010G067000.1 453 WHSSPLIAASAWQ 465
                         ************6 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF120415.2E-10238IPR021914Transcriptional factor DELLA, N-terminal
PROSITE profilePS5098563.12174445IPR005202Transcription factor GRAS
PfamPF035146.7E-125100465IPR005202Transcription factor GRAS
Sequence ? help Back to Top
Protein Sequence    Length: 478 aa     Download sequence    Send to blast
MGNSPADFSQ LASDAILYNP SDLACWVDSL LTEFAEPPPT CSSDFIVDPV NNQTVVNSAW  60
TAAEPHTPQV HQNITYDEQQ SLDNQLTVVT AMEEDSGIRL VHMLMTCAEC VQSGDLSLAT  120
SLIDDMQGLL THVNTVCGIG KVAGHFIDAL SRRIFQGMGG GSVNGGSAFE NEILYHHFYE  180
ACPYLKFAHF TANQAILEAF DGHDCVHVVD FNLMHGLQWP ALIQALALRP GGPPLLRLTG  240
IGPPSPDGRD SLREIGLRLA ELARSVNVRF AFRGVAASRL EDVKPWMLQV NPKEAVAVNS  300
IMQLHRLLGC EQTRDSPIDT VLSWIRGLNP KIMTVVEQEA NHNQPGFLDR FTEALYYYST  360
MFDSLEACRI QPEKALAEIY IQREIGNVVS CEGSARVERH EPLAKWRRRL SGAGFRALRL  420
GSNAFKQASM LLTLFSAEGY SVEENEGCLS LGWHSSPLIA ASAWQAVPAW DNHMSSS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3g_A3e-599346412378Protein SCARECROW
5b3h_A3e-599346411377Protein SCARECROW
5b3h_D3e-599346411377Protein SCARECROW
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Ubiquitously expressed. Expressed in rosette leaves, roots, stems and inflorescences of greenhouse grown. {ECO:0000269|PubMed:11877383, ECO:0000269|PubMed:9237632, ECO:0000269|PubMed:9490740}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Transcription coactivator of the zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling (PubMed:25035403). No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression. In contrast to RGA, it is less sensitive to GA. Its activity is probably regulated by other phytohormones such as auxin and ethylene. {ECO:0000269|PubMed:11487693, ECO:0000269|PubMed:11606551, ECO:0000269|PubMed:11606552, ECO:0000269|PubMed:14973286, ECO:0000269|PubMed:15128937, ECO:0000269|PubMed:16034591, ECO:0000269|PubMed:17933900, ECO:0000269|PubMed:25035403, ECO:0000269|PubMed:9389651}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGQ2906380.0GQ290638.1 Gossypium hirsutum cultivar Xinluzao-13 GAI/RGA-like 4-a gene, complete cds.
GenBankHM0347610.0HM034761.1 Gossypium hirsutum cultivar Xinluzao-13 GAI4a mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012450942.10.0PREDICTED: DELLA protein GAI-like isoform X1
SwissprotQ9LQT81e-150GAI_ARATH; DELLA protein GAI
TrEMBLA0A1U8IWT10.0A0A1U8IWT1_GOSHI; DELLA protein GAI-like
STRINGGorai.010G067000.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM160451015
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G14920.11e-134GRAS family protein
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Gallego-Giraldo C, et al.
    Role of the gibberellin receptors GID1 during fruit-set in Arabidopsis.
    Plant J., 2014. 79(6): p. 1020-1032
    [PMID:24961590]
  4. Fukazawa J, et al.
    DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis.
    Plant Cell, 2014. 26(7): p. 2920-38
    [PMID:25035403]
  5. MarĂ­n-de la Rosa N, et al.
    Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins.
    PLoS Genet., 2015. 11(7): p. e1005337
    [PMID:26134422]
  6. Shi H,Wei Y,Wang Q,Reiter RJ,He C
    Melatonin mediates the stabilization of DELLA proteins to repress the floral transition in Arabidopsis.
    J. Pineal Res., 2016. 60(3): p. 373-9
    [PMID:26887824]
  7. Lee SA, et al.
    Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue.
    Mol Plant, 2016. 9(6): p. 870-84
    [PMID:26970019]
  8. Qu J,Kang SG,Hah C,Jang JC
    Molecular and cellular characterization of GA-Stimulated Transcripts GASA4 and GASA6 in Arabidopsis thaliana.
    Plant Sci., 2016. 246: p. 1-10
    [PMID:26993231]
  9. Shahnejat-Bushehri S,Nobmann B,Devi Allu A,Balazadeh S
    JUB1 suppresses Pseudomonas syringae-induced defense responses through accumulation of DELLA proteins.
    Plant Signal Behav, 2016. 11(6): p. e1181245
    [PMID:27159137]
  10. Shahnejat-Bushehri S,Tarkowska D,Sakuraba Y,Balazadeh S
    Arabidopsis NAC transcription factor JUB1 regulates GA/BR metabolism and signalling.
    Nat Plants, 2016. 2: p. 16013
    [PMID:27249348]
  11. Wang H, et al.
    The DELLA-CONSTANS Transcription Factor Cascade Integrates Gibberellic Acid and Photoperiod Signaling to Regulate Flowering.
    Plant Physiol., 2016. 172(1): p. 479-88
    [PMID:27406167]
  12. Li W,Wang H,Yu D
    Arabidopsis WRKY Transcription Factors WRKY12 and WRKY13 Oppositely Regulate Flowering under Short-Day Conditions.
    Mol Plant, 2016. 9(11): p. 1492-1503
    [PMID:27592586]
  13. Liu B,De Storme N,Geelen D
    Gibberellin Induces Diploid Pollen Formation by Interfering with Meiotic Cytokinesis.
    Plant Physiol., 2017. 173(1): p. 338-353
    [PMID:27621423]
  14. Matsuoka K, et al.
    Differential Cellular Control by Cotyledon-Derived Phytohormones Involved in Graft Reunion of Arabidopsis Hypocotyls.
    Plant Cell Physiol., 2016. 57(12): p. 2620-2631
    [PMID:27986917]
  15. Zentella R, et al.
    The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA.
    Nat. Chem. Biol., 2017. 13(5): p. 479-485
    [PMID:28244988]
  16. Zhang Y, et al.
    GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation.
    Plant Cell Rep., 2017. 36(4): p. 557-569
    [PMID:28275852]
  17. Zhang L,Chen L,Yu D
    Transcription Factor WRKY75 Interacts with DELLA Proteins to Affect Flowering.
    Plant Physiol., 2018. 176(1): p. 790-803
    [PMID:29133369]
  18. Nelson SK,Ariizumi T,Steber CM
    Biology in the Dry Seed: Transcriptome Changes Associated with Dry Seed Dormancy and Dormancy Loss in the Arabidopsis GA-Insensitive sleepy1-2 Mutant.
    Front Plant Sci, 2017. 8: p. 2158
    [PMID:29312402]
  19. Liu B,De Storme N,Geelen D
    Cold-Induced Male Meiotic Restitution in Arabidopsis thaliana Is Not Mediated by GA-DELLA Signaling.
    Front Plant Sci, 2018. 9: p. 91
    [PMID:29459879]
  20. Zhang Y, et al.
    DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6.
    Plant Cell Rep., 2018. 37(7): p. 981-992
    [PMID:29574486]
  21. Felipo-Benavent A, et al.
    Regulation of xylem fiber differentiation by gibberellins through DELLA-KNAT1 interaction.
    Development, 2019.
    [PMID:30389856]
  22. Wright DA, et al.
    Recovery of YAC-end sequences through complementation of an Escherichia coli pyrF mutation.
    Nucleic Acids Res., 1997. 25(13): p. 2679-80
    [PMID:9185581]