PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D12G1734

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

WRKY

Protein Properties

Length: 613aa MW: 66192.2 Da PI: 6.7745

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D12G1734	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.6	3.4e-30	276	335	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+aed +++++tYeg+Hnh+ Gh_D12G1734 276 MNDGCQWRKYGQKIAKGNPCPRAYYRCTAApSCPVRKQVQRCAEDLSILITTYEGTHNHP 335 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	4.4E-32	261	337	IPR003657	WRKY domain
SuperFamily	SSF118290	2.09E-27	268	337	IPR003657	WRKY domain
PROSITE profile	PS50811	28.38	271	337	IPR003657	WRKY domain
SMART	SM00774	5.6E-36	276	336	IPR003657	WRKY domain
Pfam	PF03106	8.5E-27	277	335	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 613 aa Download sequence Send to blast
MEENLKKRSD DIGGGAVVKK EKIADSCADD EDAPALVVLP KVGDKRLCCE NDDKKPSSPG 60 KKDLSSSNNN KVSLKSDTER TEPEYSMASS STRKEQDDQL ESAKAEMGEV REENQRLKMY 120 LNRIMKDYQK LQMQFYDIVG QDSKKSQAAE NNDHHHQQEE EEPELVSLTL GRFSSDSKKD 180 GKNKASSSHG KEEERGNEGL SLGLDYKLEA SKSEVDDETL PNPSPVKGTQ ELKEEETWPP 240 SKVLKTTRTG DDEVLQQNSV KKARVCVRTR CETPTMNDGC QWRKYGQKIA KGNPCPRAYY 300 RCTAAPSCPV RKQVQRCAED LSILITTYEG THNHPLPMSA TAMASTTCAA ASMLLSGASS 360 SGSSVASLTS TANLHGLNVY LSDNSKSKFY LPNSSLSAAS SHPTITLDLT STPSSSSSFP 420 FNRFSSAYPT TSRYASTSLS FGSSESNTVS WGNGLLSYGS PSTQPYMKNP LNINGRPQST 480 MENNNIFPSF MQKNNLNPPQ QPLPDTIAAA TKAITTDPNF QSALAAALTS IIGTGNNNNG 540 GGGSGESLAQ RLKWGEQTFA VNGNGCGSSF FNKPPPSTTS QPGSLIFLPP NSLPFSTPKS 600 ASTSPGDTGN HTN

Sequence ? help Back to Top

Protein Sequence Length: 613 aa Download sequence Send to blast

MEENLKKRSD DIGGGAVVKK EKIADSCADD EDAPALVVLP KVGDKRLCCE NDDKKPSSPG  60
KKDLSSSNNN KVSLKSDTER TEPEYSMASS STRKEQDDQL ESAKAEMGEV REENQRLKMY  120
LNRIMKDYQK LQMQFYDIVG QDSKKSQAAE NNDHHHQQEE EEPELVSLTL GRFSSDSKKD  180
GKNKASSSHG KEEERGNEGL SLGLDYKLEA SKSEVDDETL PNPSPVKGTQ ELKEEETWPP  240
SKVLKTTRTG DDEVLQQNSV KKARVCVRTR CETPTMNDGC QWRKYGQKIA KGNPCPRAYY  300
RCTAAPSCPV RKQVQRCAED LSILITTYEG THNHPLPMSA TAMASTTCAA ASMLLSGASS  360
SGSSVASLTS TANLHGLNVY LSDNSKSKFY LPNSSLSAAS SHPTITLDLT STPSSSSSFP  420
FNRFSSAYPT TSRYASTSLS FGSSESNTVS WGNGLLSYGS PSTQPYMKNP LNINGRPQST  480
MENNNIFPSF MQKNNLNPPQ QPLPDTIAAA TKAITTDPNF QSALAAALTS IIGTGNNNNG  540
GGGSGESLAQ RLKWGEQTFA VNGNGCGSSF FNKPPPSTTS QPGSLIFLPP NSLPFSTPKS  600
ASTSPGDTGN HTN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	3e-22	267	337	8	77	Probable WRKY transcription factor 4
2lex_A	3e-22	267	337	8	77	Probable WRKY transcription factor 4
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, trichomes and fruits. {ECO:0000269\|PubMed:24884371}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM438477	0.0	KM438477.1 Gossypium aridum WRKY107 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016736350.1	0.0	PREDICTED: probable WRKY transcription factor 61 isoform X1
Swissprot	A0A3Q7GFB5	1e-125	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1U8NBH0	0.0	A0A1U8NBH0_GOSHI; probable WRKY transcription factor 61 isoform X1
STRING	Gorai.008G191200.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2959	28	68

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G18860.1	2e-69	WRKY DNA-binding protein 61

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]