PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D12G0971

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

WRKY

Protein Properties

Length: 212aa MW: 24404.8 Da PI: 8.1529

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D12G0971	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	103.2	1.5e-32	138	196	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 ldDgy+WrKYGqK+vk+s +prsYYrCt+++C+vkk+ver +ed ++v++tYeg+Hnh+ Gh_D12G0971 138 LDDGYKWRKYGQKVVKNSLHPRSYYRCTHNNCRVKKRVERLSEDCRMVITTYEGRHNHT 196 59********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	3.1E-34	123	196	IPR003657	WRKY domain
SuperFamily	SSF118290	5.89E-29	130	197	IPR003657	WRKY domain
PROSITE profile	PS50811	29.792	133	198	IPR003657	WRKY domain
SMART	SM00774	1.1E-37	138	197	IPR003657	WRKY domain
Pfam	PF03106	3.4E-25	139	195	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 212 aa Download sequence Send to blast
MEGERGGVHN YELQVSFSTP QPINEMGFVQ FEENQVLSLL ALAHSSHHHQ ISQPLNTTTT 60 TTTTNSTAMG FTTQNNNQVV NTEDPKAVND ENNCPSKAND GNNSWWRSSA SEKSKLKVRR 120 KLREPRFCFQ TRSDVDVLDD GYKWRKYGQK VVKNSLHPRS YYRCTHNNCR VKKRVERLSE 180 DCRMVITTYE GRHNHTPSDD SNSSEHECFT SF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-26	129	195	8	74	Probable WRKY transcription factor 4
2lex_A	1e-26	129	195	8	74	Probable WRKY transcription factor 4
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	116	122	KVRRKLR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00618	PBM	Transfer from AT2G44745	Download

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KF669840	0.0	KF669840.1 Gossypium hirsutum WRKY transcription factor 45 (WRKY45) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016735116.1	1e-159	PREDICTED: probable WRKY transcription factor 12
Swissprot	Q93WY4	1e-76	WRK12_ARATH; Probable WRKY transcription factor 12
TrEMBL	A0A1U8N7N6	1e-158	A0A1U8N7N6_GOSHI; probable WRKY transcription factor 12
STRING	Gorai.008G109600.1	1e-139	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6045	25	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G44745.1	2e-70	WRKY family protein

Publications ? help Back to Top
Yu Y, et al. MlWRKY12, a novel Miscanthus transcription factor, participates in pith secondary cell wall formation and promotes flowering. Plant Sci., 2013. 212: p. 1-9 [PMID:24094048] Yang L, et al. PtrWRKY19, a novel WRKY transcription factor, contributes to the regulation of pith secondary wall formation in Populus trichocarpa. Sci Rep, 2016. 6: p. 18643 [PMID:26819184] Li W,Wang H,Yu D Arabidopsis WRKY Transcription Factors WRKY12 and WRKY13 Oppositely Regulate Flowering under Short-Day Conditions. Mol Plant, 2016. 9(11): p. 1492-1503 [PMID:27592586] Han Y, et al. WRKY12 represses GSH1 expression to negatively regulate cadmium tolerance in Arabidopsis. Plant Mol. Biol., 2019. 99(1-2): p. 149-159 [PMID:30617455]