PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D12G0725

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

GRAS

Protein Properties

Length: 454aa MW: 50942.7 Da PI: 5.2421

Description

GRAS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D12G0725	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	GRAS	333.7	3.4e-102	65	453	3	374
GRAS 3 elLlecAeavssgdlelaqalLarlselaspdgdpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklfsevsPilkfshltaNq 100 + Lle+A+a+++++ + q+l++ l+el+sp+gd+ q+l +yf++A +r+++s++++y++l++ ++++ + +++ +++ f+evsP+ +f+h+++N Gh_D12G0725 65 DILLEAATAIADRNSGRFQQLMWMLNELSSPYGDTDQKLGSYFLQASFNRMTDSGERCYRTLASVSEKTCSFETTRKMVLKFQEVSPWTTFGHVACNG 162 689*********************************************************8888876665555555566************* PP GRAS 101 aIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesg.................skeeleetgerLakfAeelgvpfefnvl 181 aI+ea+ege+++HiiD++ ++++QWp+Ll++La+R++++p+l++T++++ ++g ++ ++e+g+r++kfA+ +gvpf+fnv+ Gh_D12G0725 163 AIMEAFEGESKLHIIDISSTYCTQWPTLLESLATRTDETPHLKLTTIVATKNGgvpgsstsgtaagslasVQDIMKEIGNRMEKFARLMGVPFKFNVI 260 *********************************************99889********99988999*******************9 PP GRAS 182 vak.rledleleeLrvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnse....sFlerflealeyysalfdsleak 274 ++ +l +l+l++L++k++Eala+n+v lh++ +++++rd +++ +k+l+P++++vve+ead++ + +F+++f e+l+++ + f++l+++ Gh_D12G0725 261 HHGgDLCELDLSKLDIKEDEALAINCVGTLHSIR----AVDNRRDMMISNFKKLQPRIITVVEEEADLDVGvdgmEFVKGFQECLRWFRVYFEALDES 354 7777*************************8....8888899****************8874333344******************* PP GRAS 275 lpreseerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvksdg.yrveeesgslvlgWkdrpLvsvS 371 ++r+s+er ++Er+ gr+iv++vac+ +e++er+e +++W++r++ +GF+p+ ls+++ +++++llr++k +g + +++++ ++l Wkd+p v++S Gh_D12G0725 355 FARTSNERLMLERA-AGRAIVELVACAPSESVERREPANRWSRRFHGSGFNPLVLSDEVCDDVRALLRRYK-EGwSMTQCSDAGIFLSWKDQPEVWAS 450 **********.****************************************************.66256668899999******** PP GRAS 372 aWr 374 aWr Gh_D12G0725 451 AWR 453 8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50985	47.506	37	433	IPR005202	Transcription factor GRAS
Pfam	PF03514	1.2E-99	65	453	IPR005202	Transcription factor GRAS

Sequence ? help Back to Top
Protein Sequence Length: 454 aa Download sequence Send to blast
MSSSGLELEF FFRNTMCLTM PHPSATGTTT TTPTSIHHAF ETSEFSTFSP ARDLTFDFSG 60 KWATDILLEA ATAIADRNSG RFQQLMWMLN ELSSPYGDTD QKLGSYFLQA SFNRMTDSGE 120 RCYRTLASVS EKTCSFETTR KMVLKFQEVS PWTTFGHVAC NGAIMEAFEG ESKLHIIDIS 180 STYCTQWPTL LESLATRTDE TPHLKLTTIV ATKNGGVPGS STSGTAAGSL ASVQDIMKEI 240 GNRMEKFARL MGVPFKFNVI HHGGDLCELD LSKLDIKEDE ALAINCVGTL HSIRAVDNRR 300 DMMISNFKKL QPRIITVVEE EADLDVGVDG MEFVKGFQEC LRWFRVYFEA LDESFARTSN 360 ERLMLERAAG RAIVELVACA PSESVERREP ANRWSRRFHG SGFNPLVLSD EVCDDVRALL 420 RRYKEGWSMT QCSDAGIFLS WKDQPEVWAS AWRP

Sequence ? help Back to Top

Protein Sequence Length: 454 aa Download sequence Send to blast

MSSSGLELEF FFRNTMCLTM PHPSATGTTT TTPTSIHHAF ETSEFSTFSP ARDLTFDFSG  60
KWATDILLEA ATAIADRNSG RFQQLMWMLN ELSSPYGDTD QKLGSYFLQA SFNRMTDSGE  120
RCYRTLASVS EKTCSFETTR KMVLKFQEVS PWTTFGHVAC NGAIMEAFEG ESKLHIIDIS  180
STYCTQWPTL LESLATRTDE TPHLKLTTIV ATKNGGVPGS STSGTAAGSL ASVQDIMKEI  240
GNRMEKFARL MGVPFKFNVI HHGGDLCELD LSKLDIKEDE ALAINCVGTL HSIRAVDNRR  300
DMMISNFKKL QPRIITVVEE EADLDVGVDG MEFVKGFQEC LRWFRVYFEA LDESFARTSN  360
ERLMLERAAG RAIVELVACA PSESVERREP ANRWSRRFHG SGFNPLVLSD EVCDDVRALL  420
RRYKEGWSMT QCSDAGIFLS WKDQPEVWAS AWRP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_B	0.0	34	454	5	420	Protein SHORT-ROOT
5b3h_E	0.0	34	454	5	420	Protein SHORT-ROOT
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed in the procambium during embryogenesis. {ECO:0000269\|PubMed:10850497}.
Uniprot	TISSUE SPECIFICITY: Expressed in the stele and the quiescent center. Not detected in the ground tissue cell lineage. The SHR protein moves from the stele to a single layer of adjacent cells, where it enters the nucleus. {ECO:0000269\|PubMed:10850497, ECO:0000269\|PubMed:11565032, ECO:0000269\|PubMed:15142972, ECO:0000269\|PubMed:15314023}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor required for quiescent center cells specification and maintenance of surrounding stem cells, and for the asymmetric cell division involved in radial pattern formation in roots. Essential for both cell division and cell specification. Regulates the radial organization of the shoot axial organs and is required for normal shoot gravitropism. Directly controls the transcription of SCR, and when associated with SCR, of MGP, RLK, TRI, NUC and SCL3. {ECO:0000269\|PubMed:10850497, ECO:0000269\|PubMed:12569126, ECO:0000269\|PubMed:15314023, ECO:0000269\|PubMed:16640459, ECO:0000269\|PubMed:17446396, ECO:0000269\|PubMed:9670559}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016730728.1	0.0	PREDICTED: protein SHORT-ROOT-like, partial
Swissprot	Q9SZF7	0.0	SHR_ARATH; Protein SHORT-ROOT
TrEMBL	A0A0D2PR12	0.0	A0A0D2PR12_GOSRA; Uncharacterized protein
STRING	Gorai.008G083500.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6104	25	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37650.1	0.0	GRAS family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Muraro D, et al. Integration of hormonal signaling networks and mobile microRNAs is required for vascular patterning in Arabidopsis roots. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(2): p. 857-62 [PMID:24381155] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Gao X,Wang C,Cui H Identification of bundle sheath cell fate factors provides new tools for C3-to-C4 engineering. Plant Signal Behav, 2018. [PMID:24819776] Ahrazem O, et al. Ectopic expression of a stress-inducible glycosyltransferase from saffron enhances salt and oxidative stress tolerance in Arabidopsis while alters anchor root formation. Plant Sci., 2015. 234: p. 60-73 [PMID:25804810] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Miguel A,Milhinhos A,Novák O,Jones B,Miguel CM The SHORT-ROOT-like gene PtSHR2B is involved in Populus phellogen activity. J. Exp. Bot., 2016. 67(5): p. 1545-55 [PMID:26709311] Gong X, et al. SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root. Plant Physiol., 2016. 170(3): p. 1675-83 [PMID:26818732] Kim ES, et al. HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots. Physiol Plant, 2016. 157(2): p. 221-33 [PMID:26968317] Lee SA, et al. Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue. Mol Plant, 2016. 9(6): p. 870-84 [PMID:26970019] Li Q,Zhao Y,Yue M,Xue Y,Bao S The Protein Arginine Methylase 5 (PRMT5/SKB1) Gene Is Required for the Maintenance of Root Stem Cells in Response to DNA Damage. J Genet Genomics, 2016. 43(4): p. 187-97 [PMID:27090604] Clark NM, et al. Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy. Elife, 2017. [PMID:27288545] Yoon EK, et al. Conservation and Diversification of the SHR-SCR-SCL23 Regulatory Network in the Development of the Functional Endodermis in Arabidopsis Shoots. Mol Plant, 2016. 9(8): p. 1197-1209 [PMID:27353361] Waszczak C, et al. SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions. Plant Cell, 2016. 28(8): p. 1844-59 [PMID:27432873] Yu Q, et al. A P-Loop NTPase Regulates Quiescent Center Cell Division and Distal Stem Cell Identity through the Regulation of ROS Homeostasis in Arabidopsis Root. PLoS Genet., 2016. 12(9): p. e1006175 [PMID:27583367] Sparks EE, et al. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Dev. Cell, 2016. 39(5): p. 585-596 [PMID:27923776] Hirano Y, et al. Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD. Nat Plants, 2017. 3: p. 17010 [PMID:28211915] Henry S, et al. SHR overexpression induces the formation of supernumerary cell layers with cortex cell identity in rice. Dev. Biol., 2017. 425(1): p. 1-7 [PMID:28263767] Möller BK, et al. Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(12): p. E2533-E2539 [PMID:28265057] Kobayashi A,Miura S,Kozaki A INDETERMINATE DOMAIN PROTEIN binding sequences in the 5'-untranslated region and promoter of the SCARECROW gene play crucial and distinct roles in regulating SCARECROW expression in roots and leaves. Plant Mol. Biol., 2017. 94(1-2): p. 1-13 [PMID:28324206] Díaz-Triviño S,Long Y,Scheres B,Blilou I Analysis of a Plant Transcriptional Regulatory Network Using Transient Expression Systems. Methods Mol. Biol., 2017. 1629: p. 83-103 [PMID:28623581] Long Y, et al. In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Nature, 2017. 548(7665): p. 97-102 [PMID:28746306] Yu Q, et al. Cell-Fate Specification in Arabidopsis Roots Requires Coordinative Action of Lineage Instruction and Positional Reprogramming. Plant Physiol., 2017. 175(2): p. 816-827 [PMID:28821591] Spiegelman Z,Lee CM,Gallagher KL KinG Is a Plant-Specific Kinesin That Regulates Both Intra- and Intercellular Movement of SHORT-ROOT. Plant Physiol., 2018. 176(1): p. 392-405 [PMID:29122988] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]